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The map label for this gene is 124024559

Identifier: 124024559

GI number: 124024559

Start: 2542584

End: 2543588

Strand: Reverse

Name: 124024559

Synonym: P9303_28711

Alternate gene names: NA

Gene position: 2543588-2542584 (Counterclockwise)

Preceding gene: 124024560

Following gene: 124024558

Centisome position: 94.82

GC content: 45.27

Gene sequence:

>1005_bases
ATGACCCGCCGAACTACTGCTCTTGCTGCTGCACTATCGCTTCTGCCGTTAGGACAACCGCTGCTACTGGGATCTACTTA
TGCTCTAGCAACTGCGGCGGTGGTGCTTTCAACCCAGGCAGCACATGCTCAAAGTGCCGGTGATTATGTAAATGCAGGAA
TTGAGAAAGGTAAGCGTGGTGACTTTAAAGGAGCAATTGCTGATTTCACACGGGCAATAGAGATTGATCCGCAGTATGCC
CGTGCCTACGGCAACCGTGGTTTTGCCAAGAGTAATTTAAAAGACTATCAAGGAGCAATTACTGATTACAAAAAGGCAAT
AGAGATTGATCCGCAGTATGCCCGTGCCTACTTCAACCGTGGTTTTGCCAAGAGTAATTTAAAAGATTATCAAGGAGCAA
TTGCTGATTTCACACGGGCAATAGAGATTAATCCGCAACTTGCCGATGCCTACTTCAACCGCGGTCTTGCCAAGGATGAT
TTAAAAGATTATCAAGGAGCAATTGCTGATTACACAAAGGCAATAGAGATTAATCCGCAGTATGCCGCTGCCTACAACAA
CCGCGGTCTTGCCAAGGTTAAATCAGGAGATACTCAAGGAGCAATTGCTGATTGGGGTAAGGCGATAGAGATTAATCCGC
AGTATGCCGCTGCCTACTACAACCGCGGTCGTGCCAAATATGATTTAAAGAGTTATCAAGCAGCAATTGCTGATTACAAC
AAGGCAATAGAGATTAATCCGCAACTTGCTATTGCCTACTACAACCGCGGTCTTGCCAAGAGTGATTTACAAGACTATCA
AGCAGCAATTGCTGATTACACAAAGGCAATAGAGATTAATCCGCAACTTTCACGTGTCTACAGAAACCGTGGCATCACCA
AGGAAAACAATGGAGATTTAAAAGGTGCTTGTAGCGACTACAAAAAGGCAGTATCTCTTGGAAATCAAGGAACAACGCAA
TGGTTAAATGCCAAGGGTGGCACCTGGTGCCGCAATATGCGATGA

Upstream 100 bases:

>100_bases
CTGGTGCGACAATATGCGTTGAGGGCATAAAACAAAAGCACGCCCAATAGACCCTACAAGACAATTCCACTTACCCTTAA
AGCAACAGAGCACTTCCTTG

Downstream 100 bases:

>100_bases
GGATATAAAACAACAGCACTCCATCTAGACCTCATAAGACGCCCCACTTACCCTGAACCCAGCAGCACCCAACAGATGAC
TCGCCGCAGAAGAACGGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTRRTTALAAALSLLPLGQPLLLGSTYALATAAVVLSTQAAHAQSAGDYVNAGIEKGKRGDFKGAIADFTRAIEIDPQYA
RAYGNRGFAKSNLKDYQGAITDYKKAIEIDPQYARAYFNRGFAKSNLKDYQGAIADFTRAIEINPQLADAYFNRGLAKDD
LKDYQGAIADYTKAIEINPQYAAAYNNRGLAKVKSGDTQGAIADWGKAIEINPQYAAAYYNRGRAKYDLKSYQAAIADYN
KAIEINPQLAIAYYNRGLAKSDLQDYQAAIADYTKAIEINPQLSRVYRNRGITKENNGDLKGACSDYKKAVSLGNQGTTQ
WLNAKGGTWCRNMR

Sequences:

>Translated_334_residues
MTRRTTALAAALSLLPLGQPLLLGSTYALATAAVVLSTQAAHAQSAGDYVNAGIEKGKRGDFKGAIADFTRAIEIDPQYA
RAYGNRGFAKSNLKDYQGAITDYKKAIEIDPQYARAYFNRGFAKSNLKDYQGAIADFTRAIEINPQLADAYFNRGLAKDD
LKDYQGAIADYTKAIEINPQYAAAYNNRGLAKVKSGDTQGAIADWGKAIEINPQYAAAYYNRGRAKYDLKSYQAAIADYN
KAIEINPQLAIAYYNRGLAKSDLQDYQAAIADYTKAIEINPQLSRVYRNRGITKENNGDLKGACSDYKKAVSLGNQGTTQ
WLNAKGGTWCRNMR
>Mature_333_residues
TRRTTALAAALSLLPLGQPLLLGSTYALATAAVVLSTQAAHAQSAGDYVNAGIEKGKRGDFKGAIADFTRAIEIDPQYAR
AYGNRGFAKSNLKDYQGAITDYKKAIEIDPQYARAYFNRGFAKSNLKDYQGAIADFTRAIEINPQLADAYFNRGLAKDDL
KDYQGAIADYTKAIEINPQYAAAYNNRGLAKVKSGDTQGAIADWGKAIEINPQYAAAYYNRGRAKYDLKSYQAAIADYNK
AIEINPQLAIAYYNRGLAKSDLQDYQAAIADYTKAIEINPQLSRVYRNRGITKENNGDLKGACSDYKKAVSLGNQGTTQW
LNAKGGTWCRNMR

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=271, Percent_Identity=30.6273062730627, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI32307148, Length=271, Percent_Identity=30.6273062730627, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI310110582, Length=263, Percent_Identity=29.277566539924, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI310123097, Length=263, Percent_Identity=29.277566539924, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI310131789, Length=263, Percent_Identity=29.277566539924, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI301336134, Length=243, Percent_Identity=29.2181069958848, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI83415184, Length=243, Percent_Identity=29.2181069958848, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI170784867, Length=302, Percent_Identity=24.8344370860927, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI167466175, Length=209, Percent_Identity=23.444976076555, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI167466177, Length=209, Percent_Identity=23.444976076555, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI118766330, Length=251, Percent_Identity=24.7011952191235, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI118766328, Length=251, Percent_Identity=24.7011952191235, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI54607135, Length=187, Percent_Identity=28.3422459893048, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI224809432, Length=217, Percent_Identity=23.5023041474654, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI296531396, Length=238, Percent_Identity=23.9495798319328, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4506921, Length=93, Percent_Identity=38.7096774193548, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI24308141, Length=107, Percent_Identity=35.5140186915888, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI5803181, Length=237, Percent_Identity=26.1603375527426, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=272, Percent_Identity=30.1470588235294, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115532690, Length=272, Percent_Identity=30.1470588235294, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25147174, Length=262, Percent_Identity=22.5190839694656, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319387, Length=193, Percent_Identity=25.9067357512953, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319589, Length=222, Percent_Identity=26.1261261261261, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17647755, Length=267, Percent_Identity=29.2134831460674, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24585827, Length=267, Percent_Identity=29.2134831460674, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24585829, Length=267, Percent_Identity=29.2134831460674, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24647123, Length=251, Percent_Identity=25.0996015936255, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364285, Length=266, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581187, Length=266, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24659892, Length=189, Percent_Identity=21.6931216931217, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137540, Length=264, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920486, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076610, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 36607; Mature: 36476

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRTTALAAALSLLPLGQPLLLGSTYALATAAVVLSTQAAHAQSAGDYVNAGIEKGKRG
CCCHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
DFKGAIADFTRAIEIDPQYARAYGNRGFAKSNLKDYQGAITDYKKAIEIDPQYARAYFNR
CCCHHHHHHHHHEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GFAKSNLKDYQGAIADFTRAIEINPQLADAYFNRGLAKDDLKDYQGAIADYTKAIEINPQ
CCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCC
YAAAYNNRGLAKVKSGDTQGAIADWGKAIEINPQYAAAYYNRGRAKYDLKSYQAAIADYN
EEEHCCCCCCEEECCCCCCCCHHHCCCEEEECCHHHHHHHHCCCCEEHHHHHHHHHHHCC
KAIEINPQLAIAYYNRGLAKSDLQDYQAAIADYTKAIEINPQLSRVYRNRGITKENNGDL
CEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCCCCC
KGACSDYKKAVSLGNQGTTQWLNAKGGTWCRNMR
CCHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure 
TRRTTALAAALSLLPLGQPLLLGSTYALATAAVVLSTQAAHAQSAGDYVNAGIEKGKRG
CCHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
DFKGAIADFTRAIEIDPQYARAYGNRGFAKSNLKDYQGAITDYKKAIEIDPQYARAYFNR
CCCHHHHHHHHHEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GFAKSNLKDYQGAIADFTRAIEINPQLADAYFNRGLAKDDLKDYQGAIADYTKAIEINPQ
CCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCC
YAAAYNNRGLAKVKSGDTQGAIADWGKAIEINPQYAAAYYNRGRAKYDLKSYQAAIADYN
EEEHCCCCCCEEECCCCCCCCHHHCCCEEEECCHHHHHHHHCCCCEEHHHHHHHHHHHCC
KAIEINPQLAIAYYNRGLAKSDLQDYQAAIADYTKAIEINPQLSRVYRNRGITKENNGDL
CEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCCCCC
KGACSDYKKAVSLGNQGTTQWLNAKGGTWCRNMR
CCHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]