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The map label for this gene is murG

Identifier: 124024479

GI number: 124024479

Start: 2457801

End: 2458886

Strand: Reverse

Name: murG

Synonym: P9303_27911

Alternate gene names: 124024479

Gene position: 2458886-2457801 (Counterclockwise)

Preceding gene: 124024481

Following gene: 124024477

Centisome position: 91.66

GC content: 60.5

Gene sequence:

>1086_bases
ATGCCCAGGCTTCTGATTGCTGCAAGCGGCACCGGTGGCCATCTTTTCCCAGCACTGGCTGTTGCTGAATCCTTGCCCGC
CTCCTGGAGCGTGTGCTGGCTGGGAGTACCAGATCGCCTAGAAACCCAACTGGTGCCAGAACGCTATGAGCTGACCACTG
TGCGCGCCGGCGGTCTACAAGGTCGCGGCCTGCGCAAGCTGGTGCAGTTGCTGCAATTACTCGCTGCTACGGGCCGGGTC
AGAAAGCTACTGCGAAAGCAAGGCATCCAGACTGTTTTCACCACTGGGGGCTATATCGCTGCGCCAGCAATCTTGGCGGC
TCGCTGGTGCGGAATCCCTGTGGTGCTGCACGAATCCAATGCCATCCCCGGACGAGTGACGCGCTTATTGGGCCGCTTCT
GCCAGGTCGTGGCTGTAGGTCTCTCTGTTGCTGCCAAGCGCATCCCAGGCAGCAAAGCTGTGGTCACAGGAACACCGGTG
CGCTCGGCATTCCTTTCGCCACAGCCCTTGCCGCATTGGGTTCCTTGCGGTGATGGCCCATTGCTGGTGGTGATTGGTGG
TAGTCAAGGGGCCGTCGGACTCAACCGCATGGTGCGAGGCGCACTGCCATCGCTGCTGGAGGCCGGTTGTCGCGTGGTGC
ATCTCACCGGCAACAACGATCCAGATGTAGGAGAACTCGATCACCCCAACCTGGTGGAACAGCCTTTCAGTCATGAGATG
CCTGGTTTGCTGCAACATGCCGATCTCGCCATCAGCCGTGCGGGCGCCGGCAGCCTGAGTGAATTGGCCGTCTGTGGCAC
CCCAACCATCTTGGTGCCCTTCCCCCAAGCGGCAGACCAGCATCAAGAGGCCAACGCAGCCTGCGCCGCTGCGCTTGGGG
CTGCCGTGATCGTGCATCAACATGCAGCCGAACACCGGGCTCTTGGTCATGCTCTGGAACAACTCATGGGAGCTCGCCTA
CGCGGCAACGCTGCTGCCAGCAACCCTTTGATTCCCATGAAGCAAGGCATGATGAAGTTGGCAGTACGTGAGGCAGACCA
GCTGCTGGTGACATTGCTGAAACCACTCATCGGAGCAGGGCTTTGA

Upstream 100 bases:

>100_bases
AGCAGACTGGAGGTCAAAGCGACTGGCTTGAGATGACGCACTGGAGGCTTGAGGGCACTGCCGATAAGTTAGGCCGCACC
TTCATGCTCTGCCCGCTGCC

Downstream 100 bases:

>100_bases
GCGCAGCAAGGATGCGGCGATTGCCTGACCTCTGCTGCAAACCAATGCGCAACCAGCGCTCCCCAAGCTCTGCAAAAGAA
CGGCAGTCACGTAACAACAC

Product: undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MPRLLIAASGTGGHLFPALAVAESLPASWSVCWLGVPDRLETQLVPERYELTTVRAGGLQGRGLRKLVQLLQLLAATGRV
RKLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESNAIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPV
RSAFLSPQPLPHWVPCGDGPLLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDPDVGELDHPNLVEQPFSHEM
PGLLQHADLAISRAGAGSLSELAVCGTPTILVPFPQAADQHQEANAACAAALGAAVIVHQHAAEHRALGHALEQLMGARL
RGNAAASNPLIPMKQGMMKLAVREADQLLVTLLKPLIGAGL

Sequences:

>Translated_361_residues
MPRLLIAASGTGGHLFPALAVAESLPASWSVCWLGVPDRLETQLVPERYELTTVRAGGLQGRGLRKLVQLLQLLAATGRV
RKLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESNAIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPV
RSAFLSPQPLPHWVPCGDGPLLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDPDVGELDHPNLVEQPFSHEM
PGLLQHADLAISRAGAGSLSELAVCGTPTILVPFPQAADQHQEANAACAAALGAAVIVHQHAAEHRALGHALEQLMGARL
RGNAAASNPLIPMKQGMMKLAVREADQLLVTLLKPLIGAGL
>Mature_360_residues
PRLLIAASGTGGHLFPALAVAESLPASWSVCWLGVPDRLETQLVPERYELTTVRAGGLQGRGLRKLVQLLQLLAATGRVR
KLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESNAIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPVR
SAFLSPQPLPHWVPCGDGPLLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDPDVGELDHPNLVEQPFSHEMP
GLLQHADLAISRAGAGSLSELAVCGTPTILVPFPQAADQHQEANAACAAALGAAVIVHQHAAEHRALGHALEQLMGARLR
GNAAASNPLIPMKQGMMKLAVREADQLLVTLLKPLIGAGL

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=310, Percent_Identity=36.4516129032258, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_PROM3 (A2CDG1)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001018786.1
- ProteinModelPortal:   A2CDG1
- SMR:   A2CDG1
- STRING:   A2CDG1
- GeneID:   4778481
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_27911
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   CLSK2392236
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37707; Mature: 37576

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLLIAASGTGGHLFPALAVAESLPASWSVCWLGVPDRLETQLVPERYELTTVRAGGLQ
CCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCEEEEEEECCCCC
GRGLRKLVQLLQLLAATGRVRKLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCC
AIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPVRSAFLSPQPLPHWVPCGDGP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCCCCEECCCCCC
LLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDPDVGELDHPNLVEQPFSHEM
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHCCCCCCCC
PGLLQHADLAISRAGAGSLSELAVCGTPTILVPFPQAADQHQEANAACAAALGAAVIVHQ
CHHHHHHHHHHHCCCCCCHHHEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HAAEHRALGHALEQLMGARLRGNAAASNPLIPMKQGMMKLAVREADQLLVTLLKPLIGAG
HHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
L
C
>Mature Secondary Structure 
PRLLIAASGTGGHLFPALAVAESLPASWSVCWLGVPDRLETQLVPERYELTTVRAGGLQ
CCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCEEEEEEECCCCC
GRGLRKLVQLLQLLAATGRVRKLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCC
AIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPVRSAFLSPQPLPHWVPCGDGP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCCCCEECCCCCC
LLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDPDVGELDHPNLVEQPFSHEM
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHCCCCCCCC
PGLLQHADLAISRAGAGSLSELAVCGTPTILVPFPQAADQHQEANAACAAALGAAVIVHQ
CHHHHHHHHHHHCCCCCCHHHEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HAAEHRALGHALEQLMGARLRGNAAASNPLIPMKQGMMKLAVREADQLLVTLLKPLIGAG
HHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA