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The map label for this gene is malZ [C]

Identifier: 124023862

GI number: 124023862

Start: 1924892

End: 1926343

Strand: Reverse

Name: malZ [C]

Synonym: P9303_21691

Alternate gene names: 124023862

Gene position: 1926343-1924892 (Counterclockwise)

Preceding gene: 124023866

Following gene: 124023858

Centisome position: 71.81

GC content: 55.1

Gene sequence:

>1452_bases
ATGCAATGGGGCATGCAGCAGATCGATGGGCTGACCAATACTCCCCGCTGGGTTGCCCAGGCGGTGGTGTATCAGATCTT
CCCTGATCGTTTTCGTTGTAGTGGCCGTGTCTTAGCTCATCAGCATTTGGCTTTGCGCTGCTGGGGCAGTGACCCTTCTG
AGCAGGGTTTTCAGGGGGGAGATCTCTACGGGGTGATCGAGGCCCTTGATCATCTCCAGGCGCTTGGTATCAGCTGCCTT
TACTTGACACCCGTCTTTAGCTCTGCCGCTAACCATCGCTATCACGCTTATGACTACTTGCAGGTGGATCCGCTTCTTGG
TGGCAATGCAGCGCTAGAGGCTTTGATTGAGGCGGTGCATCGCCGCGGGATGCGCATCATTTTGGATGGCGTGTTTAATC
ACTGTGGTCGCGGGTTCTGGGCTTTTCATCATCTTTTGGAAAATGGTGAGGCTTCGCCTTATCGCGATTGGTTTGAGGTG
CGGCAATGGCCGCTTCATCCCTATCCACGGCGTGGGCAGGATTGTGGTTACAGCTGCTGGTGGAACGATCCAGCCTTGCC
AAAGTTCAATCATGCCCATGCCCCTGTGCGTGAGTATTTGATTGCTGTAGCCCGCTATTGGCTCGAGCAGGGAATCGATG
GTTGGCGACTTGACGTTGCTGATGAGGTGCCTGCTGAGTTTTGGCTGGAGTTTCGGCAAATGGTTAAGGCCGTGAATCCA
GACGCTTGGATCTTGGCTGAGATCTGGGGTGATGCGAGATCGTGGCTACAGGGGCAGCACTTTGATGGTGTGATGAATTA
TCGGATGGGTTGGAGCAGCCTTTGCTGGGTTGCTGGTAAGCGATTACGCCGTCGGTATCGCAATCCTGCCTATCCCCTTG
ACCCTCTGAGTGGGGAGGCTTTTGTTGAGCTATTGGCAACAACGCTGGGTTGGTATCGACCTGAGGTGAACCGCAGCCAG
TTGAACCTGCTTGATAGCCACGATGTGCCGAGAGCTCTGCACACACTTCACGGTGATCTTGCGGCGTTGAAGTTGGCCTT
GCTGTTGCTGTTTTTGCAACCAGGGGCGCCTTGCATCTACTACGGCACAGAGGCGGGTTTGCAGGGTGGCCCTGAACCAG
GTTGCCGCGAAGGGTTTCCTTGGCATACGCCTTGGCCTGCAGACCTGCGCGATTTCATTCAGTCGTTGAGTGATCTGCGC
CAACGTTGCCCAGCGTTTGCTGATGGCGGTTTGCAATGGCAACCGATTGGAGCTGATGCACTTCATGCTTGGTGGATGCA
GCCCGAGACAACCACAACGCAAAGGGAGACGTCGATTCAGGTGTGGGTCAATCGCAGTCGCAGGTCATGGTTGCCGACGA
AAGTCTCATCGACAGACCCTCTTTGGCTGGAAGGAGCATTTGAATGCAATGGCCGGGGATTAGGCCCTCAATCAGCAGTG
TTGTTGAGCTGA

Upstream 100 bases:

>100_bases
GGCGGCCCTGGAGCTACTGGTGCTCTGAGCGTGATCCAGGCTTAGGAGCTGATCATCCATGGCTGTTCTCTTGTTCAAGT
GCTAGCGGTGGGATCTTGAT

Downstream 100 bases:

>100_bases
TCAAGATCACCTCTACGTTTAGTCCTCTTCAAATCGGTAGTTTTTGGAGAGGCGGAAGACAGTGCCTGAGAGCAGCACCA
GTGCGATCAAGTTAGGAATC

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: CDase; Cyclomaltodextrin hydrolase, decycling [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MQWGMQQIDGLTNTPRWVAQAVVYQIFPDRFRCSGRVLAHQHLALRCWGSDPSEQGFQGGDLYGVIEALDHLQALGISCL
YLTPVFSSAANHRYHAYDYLQVDPLLGGNAALEALIEAVHRRGMRIILDGVFNHCGRGFWAFHHLLENGEASPYRDWFEV
RQWPLHPYPRRGQDCGYSCWWNDPALPKFNHAHAPVREYLIAVARYWLEQGIDGWRLDVADEVPAEFWLEFRQMVKAVNP
DAWILAEIWGDARSWLQGQHFDGVMNYRMGWSSLCWVAGKRLRRRYRNPAYPLDPLSGEAFVELLATTLGWYRPEVNRSQ
LNLLDSHDVPRALHTLHGDLAALKLALLLLFLQPGAPCIYYGTEAGLQGGPEPGCREGFPWHTPWPADLRDFIQSLSDLR
QRCPAFADGGLQWQPIGADALHAWWMQPETTTTQRETSIQVWVNRSRRSWLPTKVSSTDPLWLEGAFECNGRGLGPQSAV
LLS

Sequences:

>Translated_483_residues
MQWGMQQIDGLTNTPRWVAQAVVYQIFPDRFRCSGRVLAHQHLALRCWGSDPSEQGFQGGDLYGVIEALDHLQALGISCL
YLTPVFSSAANHRYHAYDYLQVDPLLGGNAALEALIEAVHRRGMRIILDGVFNHCGRGFWAFHHLLENGEASPYRDWFEV
RQWPLHPYPRRGQDCGYSCWWNDPALPKFNHAHAPVREYLIAVARYWLEQGIDGWRLDVADEVPAEFWLEFRQMVKAVNP
DAWILAEIWGDARSWLQGQHFDGVMNYRMGWSSLCWVAGKRLRRRYRNPAYPLDPLSGEAFVELLATTLGWYRPEVNRSQ
LNLLDSHDVPRALHTLHGDLAALKLALLLLFLQPGAPCIYYGTEAGLQGGPEPGCREGFPWHTPWPADLRDFIQSLSDLR
QRCPAFADGGLQWQPIGADALHAWWMQPETTTTQRETSIQVWVNRSRRSWLPTKVSSTDPLWLEGAFECNGRGLGPQSAV
LLS
>Mature_483_residues
MQWGMQQIDGLTNTPRWVAQAVVYQIFPDRFRCSGRVLAHQHLALRCWGSDPSEQGFQGGDLYGVIEALDHLQALGISCL
YLTPVFSSAANHRYHAYDYLQVDPLLGGNAALEALIEAVHRRGMRIILDGVFNHCGRGFWAFHHLLENGEASPYRDWFEV
RQWPLHPYPRRGQDCGYSCWWNDPALPKFNHAHAPVREYLIAVARYWLEQGIDGWRLDVADEVPAEFWLEFRQMVKAVNP
DAWILAEIWGDARSWLQGQHFDGVMNYRMGWSSLCWVAGKRLRRRYRNPAYPLDPLSGEAFVELLATTLGWYRPEVNRSQ
LNLLDSHDVPRALHTLHGDLAALKLALLLLFLQPGAPCIYYGTEAGLQGGPEPGCREGFPWHTPWPADLRDFIQSLSDLR
QRCPAFADGGLQWQPIGADALHAWWMQPETTTTQRETSIQVWVNRSRRSWLPTKVSSTDPLWLEGAFECNGRGLGPQSAV
LLS

Specific function: Hydrolyzes cyclodextrins. Can also act on linear maltodextrins, with the exception of maltose [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=461, Percent_Identity=22.7765726681128, Blast_Score=96, Evalue=8e-20,
Organism=Escherichia coli, GI1786604, Length=441, Percent_Identity=34.4671201814059, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1790687, Length=230, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1789995, Length=499, Percent_Identity=25.8517034068136, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322245, Length=233, Percent_Identity=27.8969957081545, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6322241, Length=229, Percent_Identity=27.9475982532751, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322021, Length=229, Percent_Identity=27.9475982532751, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324416, Length=229, Percent_Identity=27.9475982532751, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321726, Length=229, Percent_Identity=27.9475982532751, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319776, Length=239, Percent_Identity=26.7782426778243, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321731, Length=239, Percent_Identity=26.7782426778243, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24586593, Length=238, Percent_Identity=26.0504201680672, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24586591, Length=233, Percent_Identity=27.0386266094421, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24586587, Length=224, Percent_Identity=25.4464285714286, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24586589, Length=224, Percent_Identity=26.3392857142857, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330053, Length=179, Percent_Identity=27.9329608938547, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.54 [H]

Molecular weight: Translated: 55062; Mature: 55062

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQWGMQQIDGLTNTPRWVAQAVVYQIFPDRFRCSGRVLAHQHLALRCWGSDPSEQGFQGG
CCCCHHHHCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEEECCEEEEECCCCCCCCCCCCC
DLYGVIEALDHLQALGISCLYLTPVFSSAANHRYHAYDYLQVDPLLGGNAALEALIEAVH
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHH
RRGMRIILDGVFNHCGRGFWAFHHLLENGEASPYRDWFEVRQWPLHPYPRRGQDCGYSCW
HCCCEEHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEE
WNDPALPKFNHAHAPVREYLIAVARYWLEQGIDGWRLDVADEVPAEFWLEFRQMVKAVNP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHCCHHHHHHHHHHHHHCCC
DAWILAEIWGDARSWLQGQHFDGVMNYRMGWSSLCWVAGKRLRRRYRNPAYPLDPLSGEA
CCEEHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
FVELLATTLGWYRPEVNRSQLNLLDSHDVPRALHTLHGDLAALKLALLLLFLQPGAPCIY
HHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
YGTEAGLQGGPEPGCREGFPWHTPWPADLRDFIQSLSDLRQRCPAFADGGLQWQPIGADA
ECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHH
LHAWWMQPETTTTQRETSIQVWVNRSRRSWLPTKVSSTDPLWLEGAFECNGRGLGPQSAV
HHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECEEEECCCCCCCCCCE
LLS
ECC
>Mature Secondary Structure
MQWGMQQIDGLTNTPRWVAQAVVYQIFPDRFRCSGRVLAHQHLALRCWGSDPSEQGFQGG
CCCCHHHHCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEEECCEEEEECCCCCCCCCCCCC
DLYGVIEALDHLQALGISCLYLTPVFSSAANHRYHAYDYLQVDPLLGGNAALEALIEAVH
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHH
RRGMRIILDGVFNHCGRGFWAFHHLLENGEASPYRDWFEVRQWPLHPYPRRGQDCGYSCW
HCCCEEHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEE
WNDPALPKFNHAHAPVREYLIAVARYWLEQGIDGWRLDVADEVPAEFWLEFRQMVKAVNP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHCCHHHHHHHHHHHHHCCC
DAWILAEIWGDARSWLQGQHFDGVMNYRMGWSSLCWVAGKRLRRRYRNPAYPLDPLSGEA
CCEEHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
FVELLATTLGWYRPEVNRSQLNLLDSHDVPRALHTLHGDLAALKLALLLLFLQPGAPCIY
HHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
YGTEAGLQGGPEPGCREGFPWHTPWPADLRDFIQSLSDLRQRCPAFADGGLQWQPIGADA
ECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHH
LHAWWMQPETTTTQRETSIQVWVNRSRRSWLPTKVSSTDPLWLEGAFECNGRGLGPQSAV
HHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECEEEECCCCCCCCCCE
LLS
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7763728 [H]