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The map label for this gene is aroQ [H]

Identifier: 124023855

GI number: 124023855

Start: 1920294

End: 1920788

Strand: Reverse

Name: aroQ [H]

Synonym: P9303_21621

Alternate gene names: 124023855

Gene position: 1920788-1920294 (Counterclockwise)

Preceding gene: 124023856

Following gene: 124023854

Centisome position: 71.6

GC content: 55.35

Gene sequence:

>495_bases
GTGGGGATCGATACGATCCATTCACCCCCTTCATGCTTCAGGGCCATGCGACTGCTGCTGCTCAACGGCCCCAATCTCAA
CCTTCTCGGTCAACGAGAGCCTGGTGTTTATGGAGTCATGACGTTGAAAGCGATTGAGGCAGACCTGCTCGCTCAGGCGG
AGGCAGAAGCGGTTCAGCTTGAGTGTTTCCAGAGCAACTTTGAAGGTGCTTTGGTGGATCGCATCCATCAAGCCATCGGC
CAGGTGCAAGGAATCCTGATCAATGCTGGGGCCTATACCCATACCTCGATTGCTTTACGGGATGCTCTGCTCGGAGCAGC
GATTCCATACGTGGAGTTGCATCTCAGCAATACCCATGCCCGTGAGGGCTTCCGGCATCACTCTTATCTCGCTGATCGCG
CTGTGGGTGTGGTGAGCGGTTTTGGTGCATTGAGCTATCGCCTTGCTTTGGAAGGCTTGCTGGCTCATTTGCGTCAGCCG
CAGCAGGCTCTATGA

Upstream 100 bases:

>100_bases
ACAGTCCGCCCCCATTAACCACTCGGGCACCGACCCGAACCACACCTGCTGACATTACCAGCAGATCGCACCTTTGTGGC
TGAATGTCTGGGAAGGTCTT

Downstream 100 bases:

>100_bases
GTGCTCTTGCTGCTGCTAAGACGTCAAACGCCAAGATCAAATGGCTGGCGGCTCCCACCAGTGATGCTTGGTTGGAGCAG
GCGATTGCTCATCCGCTCGA

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MGIDTIHSPPSCFRAMRLLLLNGPNLNLLGQREPGVYGVMTLKAIEADLLAQAEAEAVQLECFQSNFEGALVDRIHQAIG
QVQGILINAGAYTHTSIALRDALLGAAIPYVELHLSNTHAREGFRHHSYLADRAVGVVSGFGALSYRLALEGLLAHLRQP
QQAL

Sequences:

>Translated_164_residues
MGIDTIHSPPSCFRAMRLLLLNGPNLNLLGQREPGVYGVMTLKAIEADLLAQAEAEAVQLECFQSNFEGALVDRIHQAIG
QVQGILINAGAYTHTSIALRDALLGAAIPYVELHLSNTHAREGFRHHSYLADRAVGVVSGFGALSYRLALEGLLAHLRQP
QQAL
>Mature_163_residues
GIDTIHSPPSCFRAMRLLLLNGPNLNLLGQREPGVYGVMTLKAIEADLLAQAEAEAVQLECFQSNFEGALVDRIHQAIGQ
VQGILINAGAYTHTSIALRDALLGAAIPYVELHLSNTHAREGFRHHSYLADRAVGVVSGFGALSYRLALEGLLAHLRQPQ
QAL

Specific function: Catalyzes a trans-dehydration via an enolate intermediate [H]

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001874
- InterPro:   IPR018509
- ProDom:   PD004527 [H]

Pfam domain/function: PF01220 DHquinase_II [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 17718; Mature: 17586

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIDTIHSPPSCFRAMRLLLLNGPNLNLLGQREPGVYGVMTLKAIEADLLAQAEAEAVQL
CCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
ECFQSNFEGALVDRIHQAIGQVQGILINAGAYTHTSIALRDALLGAAIPYVELHLSNTHA
HHHHCCCCCHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHCCEEEEEECCCHH
REGFRHHSYLADRAVGVVSGFGALSYRLALEGLLAHLRQPQQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
GIDTIHSPPSCFRAMRLLLLNGPNLNLLGQREPGVYGVMTLKAIEADLLAQAEAEAVQL
CCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
ECFQSNFEGALVDRIHQAIGQVQGILINAGAYTHTSIALRDALLGAAIPYVELHLSNTHA
HHHHCCCCCHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHCCEEEEEECCCHH
REGFRHHSYLADRAVGVVSGFGALSYRLALEGLLAHLRQPQQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]