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The map label for this gene is cvrA [H]

Identifier: 124023421

GI number: 124023421

Start: 1500167

End: 1501357

Strand: Reverse

Name: cvrA [H]

Synonym: P9303_17191

Alternate gene names: 124023421

Gene position: 1501357-1500167 (Counterclockwise)

Preceding gene: 124023424

Following gene: 124023418

Centisome position: 55.96

GC content: 52.81

Gene sequence:

>1191_bases
GTGATCTTCGCCTATTGCCTGCTTTCAAGACGATTGTCCAGGACAGCAGTCTCTGGACCACTGGTCTTTGTTGCGCTGGG
CTTAGTCCTTGGCCCTGCCAACCTGGGCTGGCTCAACATCTCACTGGATTCAGCGCTGCTAAGGCGTCTGGCTGAGATCA
CATTGGGTCTTGTGTTGTTCACCGATGCAGCAGCCTTGGACTGGGCTGTGTTACGCAACAGTGCCCGCCTGCCAATGCGT
CTGCTGCTGCTCGGACTGCCACTCAGCATTCTGATGGGTTTCGTGGTAGCCCGATTGATATTGCCTGAACTAGGCCTGAT
TGAAGCAGTCCTACTTGCTGTGGTGCTCGCTCCAACAGATGCGGCACTTGGCGAAGCCGTGACCACCAACCTCGAAGTAC
CAGAAGCTATCCGCGAAGACCTCAATGTTGAAAGTGGCCTCAATGACGGAATTTGTGTTCCTATGTTGTTGTGTTTTCTT
GGCATCTCAACTGGTCATCTTGACCAGATCAATGGACCGAAGGATGCATTGCAGAGCTTCGGCCAGCTGCTTGTCAGTGA
AATAGGTATCGGCCTCGTGATAGGAGCCTTTATTGGATTATTGGGTAGTTGGTTAAGGGATCAGGCAGAACAACGCAAAT
GGATTGCTGAGGATTGGAGGCCTTTGATCACGGTGGCCCTGGCCCTGAGTGCCTACACCCTCGCCCAAACCCTCCATGGG
AGCGGATTCATTTCCTGTTTCATCGCTGGTCTTCTCTATGGGATCTGCAGTCGCAAAGAACTCAAGGACGGTGAGATGGT
GGCTTCTCTGGCAATGGGTGACATGTTGGCCCTACTGACCTGGGTTCTATTTGGCAGTGCCATGGTGCCCGATGCCTGGA
GCAACATCACAGTCGCAAGTGTTGTCTATGGGGCTTTAAGCCTGACACTAGTGCGCATTGTTCCGGTTGCCTTAGCAACA
AGCGGCCTTGGACTTGATCACTGGACGAAACTCTTCGTTGGTTGGTTTGGGCCAAGAGGTTTAGCCAGCATTGTGTTTGT
TGTGATGGTGGTAGACGCGGCGCTTCCAAACGCACAAGCGATCCTTACTACCACAACGGTCACCATTGTTTTGAGTGTGA
TTGCCCATGGCATTACAGCTAACCGGTTTTCGATGTTCTACGGCCGCTGGGAAAGAAGTCATGCCGGCTGA

Upstream 100 bases:

>100_bases
ATTTTGAGATCTACATCCGAATTATGGGCAGCATCAAGGGGACACAAACTCACCACTAGCCGTGCTGCACAGCGACCTTG
ACCTGGCAGTGATCAGTTTA

Downstream 100 bases:

>100_bases
AATAAAGAAGATTGAGTTTATAAAGACAAAACAAAAAAGACGAAAGCTCAAAAGAACACGCCAGTCAAAGGAACGATCTA
TTGAAATGAATGTATCTACA

Product: Na+/H+ antiporter, CPA1 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MIFAYCLLSRRLSRTAVSGPLVFVALGLVLGPANLGWLNISLDSALLRRLAEITLGLVLFTDAAALDWAVLRNSARLPMR
LLLLGLPLSILMGFVVARLILPELGLIEAVLLAVVLAPTDAALGEAVTTNLEVPEAIREDLNVESGLNDGICVPMLLCFL
GISTGHLDQINGPKDALQSFGQLLVSEIGIGLVIGAFIGLLGSWLRDQAEQRKWIAEDWRPLITVALALSAYTLAQTLHG
SGFISCFIAGLLYGICSRKELKDGEMVASLAMGDMLALLTWVLFGSAMVPDAWSNITVASVVYGALSLTLVRIVPVALAT
SGLGLDHWTKLFVGWFGPRGLASIVFVVMVVDAALPNAQAILTTTTVTIVLSVIAHGITANRFSMFYGRWERSHAG

Sequences:

>Translated_396_residues
MIFAYCLLSRRLSRTAVSGPLVFVALGLVLGPANLGWLNISLDSALLRRLAEITLGLVLFTDAAALDWAVLRNSARLPMR
LLLLGLPLSILMGFVVARLILPELGLIEAVLLAVVLAPTDAALGEAVTTNLEVPEAIREDLNVESGLNDGICVPMLLCFL
GISTGHLDQINGPKDALQSFGQLLVSEIGIGLVIGAFIGLLGSWLRDQAEQRKWIAEDWRPLITVALALSAYTLAQTLHG
SGFISCFIAGLLYGICSRKELKDGEMVASLAMGDMLALLTWVLFGSAMVPDAWSNITVASVVYGALSLTLVRIVPVALAT
SGLGLDHWTKLFVGWFGPRGLASIVFVVMVVDAALPNAQAILTTTTVTIVLSVIAHGITANRFSMFYGRWERSHAG
>Mature_396_residues
MIFAYCLLSRRLSRTAVSGPLVFVALGLVLGPANLGWLNISLDSALLRRLAEITLGLVLFTDAAALDWAVLRNSARLPMR
LLLLGLPLSILMGFVVARLILPELGLIEAVLLAVVLAPTDAALGEAVTTNLEVPEAIREDLNVESGLNDGICVPMLLCFL
GISTGHLDQINGPKDALQSFGQLLVSEIGIGLVIGAFIGLLGSWLRDQAEQRKWIAEDWRPLITVALALSAYTLAQTLHG
SGFISCFIAGLLYGICSRKELKDGEMVASLAMGDMLALLTWVLFGSAMVPDAWSNITVASVVYGALSLTLVRIVPVALAT
SGLGLDHWTKLFVGWFGPRGLASIVFVVMVVDAALPNAQAILTTTTVTIVLSVIAHGITANRFSMFYGRWERSHAG

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018421
- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 42256; Mature: 42256

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFAYCLLSRRLSRTAVSGPLVFVALGLVLGPANLGWLNISLDSALLRRLAEITLGLVLF
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
TDAAALDWAVLRNSARLPMRLLLLGLPLSILMGFVVARLILPELGLIEAVLLAVVLAPTD
HHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
AALGEAVTTNLEVPEAIREDLNVESGLNDGICVPMLLCFLGISTGHLDQINGPKDALQSF
HHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
GQLLVSEIGIGLVIGAFIGLLGSWLRDQAEQRKWIAEDWRPLITVALALSAYTLAQTLHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SGFISCFIAGLLYGICSRKELKDGEMVASLAMGDMLALLTWVLFGSAMVPDAWSNITVAS
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
VVYGALSLTLVRIVPVALATSGLGLDHWTKLFVGWFGPRGLASIVFVVMVVDAALPNAQA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
ILTTTTVTIVLSVIAHGITANRFSMFYGRWERSHAG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIFAYCLLSRRLSRTAVSGPLVFVALGLVLGPANLGWLNISLDSALLRRLAEITLGLVLF
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
TDAAALDWAVLRNSARLPMRLLLLGLPLSILMGFVVARLILPELGLIEAVLLAVVLAPTD
HHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
AALGEAVTTNLEVPEAIREDLNVESGLNDGICVPMLLCFLGISTGHLDQINGPKDALQSF
HHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
GQLLVSEIGIGLVIGAFIGLLGSWLRDQAEQRKWIAEDWRPLITVALALSAYTLAQTLHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SGFISCFIAGLLYGICSRKELKDGEMVASLAMGDMLALLTWVLFGSAMVPDAWSNITVAS
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
VVYGALSLTLVRIVPVALATSGLGLDHWTKLFVGWFGPRGLASIVFVVMVVDAALPNAQA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
ILTTTTVTIVLSVIAHGITANRFSMFYGRWERSHAG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA