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The map label for this gene is gltS [H]

Identifier: 124023424

GI number: 124023424

Start: 1507190

End: 1508434

Strand: Reverse

Name: gltS [H]

Synonym: P9303_17221

Alternate gene names: 124023424

Gene position: 1508434-1507190 (Counterclockwise)

Preceding gene: 124023425

Following gene: 124023421

Centisome position: 56.23

GC content: 39.68

Gene sequence:

>1245_bases
ATGGATACATTTGAAATTAGATCGCTGATATCAATCTCAATTGGCATACTTGTACTGTTTATTGGCAAGCGCATCAATGG
CAATATTCAAGTGCTGCAGAATTTATCGATTCCTGATTCTGTTACAGGCGGACTGATTGCAGCACTAGCAATCACACTTG
TGAAATGGACAACGGATATAGAGGTTATATTTGATCTTGGTGCAAGAGATTTCTTGCTTATTTATTTCTTTACTACGGTT
GGTATAAGTTCAAATTTAATCAACATGAGAAGGGGTGGGAAAGCCCTGGGAATATTACTCGGTCTGGTTATTGCTTTCAT
TACGATTCAGAACATTTTCGGTGAATGGACAGTTAATCTATTTGGACTCCAAGAAGGCCTTGGACCACTTTTGGGTTCAG
TTTCGCTTGCAGGTGGCCATGGTGTGACCATCGCATGGGCGCCAACCTTTGCAAAACAATTTGGCATCAAGAATGCTTTG
GAAATTGGCGTTGCAGCATCTACATTTGGGTTGTTGGTTGCCAGCCTAATAGGTGGGCCAATCGCCAATTACTTGATTCG
AAAAAATCATCTGAATTTAGATCATAAAAAAGAAATATATAATGAAAACAGGAATGGAGAAGAAAATACAGACAAGACGG
AATTGAATAATCAATTACCATCAAAATTGGATTACAACAGTATTCTTTCGTCAGTGCTGGCTGTCAATATCTGTATTATT
CTCGGGAAAATATGCCAGGAATTTCTTTTTAAGTTAGATATTCAACTGCCACTTTTTGTTGTTTCTATGATCGTTGGAAT
CATTTTGAGCAGCATTTTGCCGGATCGTAAGATTTTAAATGATTTTCTAATTTGGCCTAAGCAAACAGCTGCTTTATTAC
TTCTGGCAGAGCTTTCCCTTGGCACATTTCTGGCAATGTCAATCATGAGTCTGCAGTTTTGGGATCTCTTGGATCTCCCT
CCGGCCTTGCTGTTTATATTGGTTTTCCAAACTATCCTCTCTATCGTAGTCAATCTATATCTTGTTTTTCCGCTGATGGG
CCGCAACTACGACGCAGCTGTGATTTGCTCAGGATTTGCGGGCATGTCGATAGGGTCATCGGCTGCTGGGCTCGCAAATA
TGACGGCAATATCAAGGAAGTATGGGCCAACCAAAAAAGCATTTATAGTCGTGCCACTGATCGCAACATTTATTGAGATT
ATAAATTCAGGTCTTATTATTCCAGCCTCAATTAGGTTTTTATGA

Upstream 100 bases:

>100_bases
CTAGAATGACCGGTGAAATAAATAGTTACTTCTAAAGCACCTGTGCGCTAGAAGTAACTAGCCTTACAGAAATTATAATT
AAACATCAATTCAATAGGCA

Downstream 100 bases:

>100_bases
TTTATTAAATCATAAAATGAAGAATTCACCCGGCAAATTAAATTGCCAATATCTTCATGAGTGATCCGCCAAGGATAGAC
TGCTTATGCAAATCCTGAAT

Product: hypothetical protein

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MDTFEIRSLISISIGILVLFIGKRINGNIQVLQNLSIPDSVTGGLIAALAITLVKWTTDIEVIFDLGARDFLLIYFFTTV
GISSNLINMRRGGKALGILLGLVIAFITIQNIFGEWTVNLFGLQEGLGPLLGSVSLAGGHGVTIAWAPTFAKQFGIKNAL
EIGVAASTFGLLVASLIGGPIANYLIRKNHLNLDHKKEIYNENRNGEENTDKTELNNQLPSKLDYNSILSSVLAVNICII
LGKICQEFLFKLDIQLPLFVVSMIVGIILSSILPDRKILNDFLIWPKQTAALLLLAELSLGTFLAMSIMSLQFWDLLDLP
PALLFILVFQTILSIVVNLYLVFPLMGRNYDAAVICSGFAGMSIGSSAAGLANMTAISRKYGPTKKAFIVVPLIATFIEI
INSGLIIPASIRFL

Sequences:

>Translated_414_residues
MDTFEIRSLISISIGILVLFIGKRINGNIQVLQNLSIPDSVTGGLIAALAITLVKWTTDIEVIFDLGARDFLLIYFFTTV
GISSNLINMRRGGKALGILLGLVIAFITIQNIFGEWTVNLFGLQEGLGPLLGSVSLAGGHGVTIAWAPTFAKQFGIKNAL
EIGVAASTFGLLVASLIGGPIANYLIRKNHLNLDHKKEIYNENRNGEENTDKTELNNQLPSKLDYNSILSSVLAVNICII
LGKICQEFLFKLDIQLPLFVVSMIVGIILSSILPDRKILNDFLIWPKQTAALLLLAELSLGTFLAMSIMSLQFWDLLDLP
PALLFILVFQTILSIVVNLYLVFPLMGRNYDAAVICSGFAGMSIGSSAAGLANMTAISRKYGPTKKAFIVVPLIATFIEI
INSGLIIPASIRFL
>Mature_414_residues
MDTFEIRSLISISIGILVLFIGKRINGNIQVLQNLSIPDSVTGGLIAALAITLVKWTTDIEVIFDLGARDFLLIYFFTTV
GISSNLINMRRGGKALGILLGLVIAFITIQNIFGEWTVNLFGLQEGLGPLLGSVSLAGGHGVTIAWAPTFAKQFGIKNAL
EIGVAASTFGLLVASLIGGPIANYLIRKNHLNLDHKKEIYNENRNGEENTDKTELNNQLPSKLDYNSILSSVLAVNICII
LGKICQEFLFKLDIQLPLFVVSMIVGIILSSILPDRKILNDFLIWPKQTAALLLLAELSLGTFLAMSIMSLQFWDLLDLP
PALLFILVFQTILSIVVNLYLVFPLMGRNYDAAVICSGFAGMSIGSSAAGLANMTAISRKYGPTKKAFIVVPLIATFIEI
INSGLIIPASIRFL

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=383, Percent_Identity=35.509138381201, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 44942; Mature: 44942

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTFEIRSLISISIGILVLFIGKRINGNIQVLQNLSIPDSVTGGLIAALAITLVKWTTDI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCH
EVIFDLGARDFLLIYFFTTVGISSNLINMRRGGKALGILLGLVIAFITIQNIFGEWTVNL
HHHEECCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEE
FGLQEGLGPLLGSVSLAGGHGVTIAWAPTFAKQFGIKNALEIGVAASTFGLLVASLIGGP
HHHHHHHHHHHHCCEECCCCCEEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCH
IANYLIRKNHLNLDHKKEIYNENRNGEENTDKTELNNQLPSKLDYNSILSSVLAVNICII
HHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LGKICQEFLFKLDIQLPLFVVSMIVGIILSSILPDRKILNDFLIWPKQTAALLLLAELSL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHH
GTFLAMSIMSLQFWDLLDLPPALLFILVFQTILSIVVNLYLVFPLMGRNYDAAVICSGFA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GMSIGSSAAGLANMTAISRKYGPTKKAFIVVPLIATFIEIINSGLIIPASIRFL
CCCCCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure
MDTFEIRSLISISIGILVLFIGKRINGNIQVLQNLSIPDSVTGGLIAALAITLVKWTTDI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCH
EVIFDLGARDFLLIYFFTTVGISSNLINMRRGGKALGILLGLVIAFITIQNIFGEWTVNL
HHHEECCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEE
FGLQEGLGPLLGSVSLAGGHGVTIAWAPTFAKQFGIKNALEIGVAASTFGLLVASLIGGP
HHHHHHHHHHHHCCEECCCCCEEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCH
IANYLIRKNHLNLDHKKEIYNENRNGEENTDKTELNNQLPSKLDYNSILSSVLAVNICII
HHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LGKICQEFLFKLDIQLPLFVVSMIVGIILSSILPDRKILNDFLIWPKQTAALLLLAELSL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHH
GTFLAMSIMSLQFWDLLDLPPALLFILVFQTILSIVVNLYLVFPLMGRNYDAAVICSGFA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GMSIGSSAAGLANMTAISRKYGPTKKAFIVVPLIATFIEIINSGLIIPASIRFL
CCCCCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]