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The map label for this gene is proX [H]

Identifier: 124023399

GI number: 124023399

Start: 1484464

End: 1485318

Strand: Reverse

Name: proX [H]

Synonym: P9303_16971

Alternate gene names: 124023399

Gene position: 1485318-1484464 (Counterclockwise)

Preceding gene: 124023400

Following gene: 124023396

Centisome position: 55.37

GC content: 49.47

Gene sequence:

>855_bases
ATGACTGGCTTGTCGGGATGTTCGAACGCCAAACCAGATCAATTGCGCATCGGCTGGACTGCCTGGGCTGATGCTGACGT
AGTAAGCCTGATGGCTGAAAAACTAATCGAAAGCCACTATGAGCAGCCTGTCGAACGAGTTATGGCAGATATCGGTATTC
AGTACGACTCTGTTGCTCGCGGGAAGCTCGATCTGATGTTAATGGCATGGCTGCCAAAAACACACGATAAATACTGGCAA
AAAGTAAGCGATCGAGTTGTAGATCTTGGCACGATGTACTCAGGTCGCATTGGCTGGGTAGTCCCTGACTATGTGCCAAA
ACAACGTATTGGCTCCATTAGCGATCTGAGCGACCCGAAAATTGCTAACGACTTCAACAACACAGTGCAAGGGATAGACC
CGGGATCAGGGCTGATGCAGGCATCTGAGAAAGCGCTAACTGCCTATGACCTATCGGATCTGAAACTGATTTCAGCGAGT
GGTGCCGCAATGACAGCCGTTCTCGATCGGGCTATCAATGACGATCGATGGGTCGTGGTAACTGGTTGGACCCCTCACTG
GATGTTTGCCCGCTATAAACTCCGCTTTTTGAAGGATCCCAAGAGTGTTTTTGGTGGCCAAGAAGGCATCCATGCCATTG
CACGCCTAGGGCTGGACAAAGACCATCCTAAAGTGGTCGCCTTTTTCACCCGCTTCAAGCTGTCGGATGGTCAGCTGGAT
GCCATGCTATTGGATGCTGAGAACACCTCAACAGAGGAAGCCGTTAATAATTACATAGCCAACAATCGGAATCAAATTGA
CTACTGGATGAACGGCACTATGCAAGAGCCGAAAGATAGAGAAGCCAAACCATAA

Upstream 100 bases:

>100_bases
CATTGCCGCAGCGCTTTAAAGCCTTTACTAACCTCTGGACTTCCTCATGAAAATGTCTGACAAGTTGCGAAATCTAAGCC
TTGTTATCGCTGGAGTGCTG

Downstream 100 bases:

>100_bases
CCACCCGCTCAGCTCTTGAGCTGCTTAATCAGTTGACTTCCCTTAGACAATATCTGACATCAAAGAGCTTTCAAGACCAA
AGCGAATTGCTTCAGCTGCT

Product: glycine/betaine ABC transporter substrate-binding protein

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTGLSGCSNAKPDQLRIGWTAWADADVVSLMAEKLIESHYEQPVERVMADIGIQYDSVARGKLDLMLMAWLPKTHDKYWQ
KVSDRVVDLGTMYSGRIGWVVPDYVPKQRIGSISDLSDPKIANDFNNTVQGIDPGSGLMQASEKALTAYDLSDLKLISAS
GAAMTAVLDRAINDDRWVVVTGWTPHWMFARYKLRFLKDPKSVFGGQEGIHAIARLGLDKDHPKVVAFFTRFKLSDGQLD
AMLLDAENTSTEEAVNNYIANNRNQIDYWMNGTMQEPKDREAKP

Sequences:

>Translated_284_residues
MTGLSGCSNAKPDQLRIGWTAWADADVVSLMAEKLIESHYEQPVERVMADIGIQYDSVARGKLDLMLMAWLPKTHDKYWQ
KVSDRVVDLGTMYSGRIGWVVPDYVPKQRIGSISDLSDPKIANDFNNTVQGIDPGSGLMQASEKALTAYDLSDLKLISAS
GAAMTAVLDRAINDDRWVVVTGWTPHWMFARYKLRFLKDPKSVFGGQEGIHAIARLGLDKDHPKVVAFFTRFKLSDGQLD
AMLLDAENTSTEEAVNNYIANNRNQIDYWMNGTMQEPKDREAKP
>Mature_283_residues
TGLSGCSNAKPDQLRIGWTAWADADVVSLMAEKLIESHYEQPVERVMADIGIQYDSVARGKLDLMLMAWLPKTHDKYWQK
VSDRVVDLGTMYSGRIGWVVPDYVPKQRIGSISDLSDPKIANDFNNTVQGIDPGSGLMQASEKALTAYDLSDLKLISASG
AAMTAVLDRAINDDRWVVVTGWTPHWMFARYKLRFLKDPKSVFGGQEGIHAIARLGLDKDHPKVVAFFTRFKLSDGQLDA
MLLDAENTSTEEAVNNYIANNRNQIDYWMNGTMQEPKDREAKP

Specific function: Involved in a multicomponent binding-protein-dependent transport system for glycine betaine [H]

COG id: COG2113

COG function: function code E; ABC-type proline/glycine betaine transport systems, periplasmic components

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 31788; Mature: 31657

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLSGCSNAKPDQLRIGWTAWADADVVSLMAEKLIESHYEQPVERVMADIGIQYDSVAR
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GKLDLMLMAWLPKTHDKYWQKVSDRVVDLGTMYSGRIGWVVPDYVPKQRIGSISDLSDPK
CCCEEEHEECCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHCCCCCCCCCCC
IANDFNNTVQGIDPGSGLMQASEKALTAYDLSDLKLISASGAAMTAVLDRAINDDRWVVV
HHCCHHCCCCCCCCCCHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHHCCCCCEEEE
TGWTPHWMFARYKLRFLKDPKSVFGGQEGIHAIARLGLDKDHPKVVAFFTRFKLSDGQLD
ECCCCHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEHEECCCCCEE
AMLLDAENTSTEEAVNNYIANNRNQIDYWMNGTMQEPKDREAKP
EEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TGLSGCSNAKPDQLRIGWTAWADADVVSLMAEKLIESHYEQPVERVMADIGIQYDSVAR
CCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GKLDLMLMAWLPKTHDKYWQKVSDRVVDLGTMYSGRIGWVVPDYVPKQRIGSISDLSDPK
CCCEEEHEECCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHCCCCCCCCCCC
IANDFNNTVQGIDPGSGLMQASEKALTAYDLSDLKLISASGAAMTAVLDRAINDDRWVVV
HHCCHHCCCCCCCCCCHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHHCCCCCEEEE
TGWTPHWMFARYKLRFLKDPKSVFGGQEGIHAIARLGLDKDHPKVVAFFTRFKLSDGQLD
ECCCCHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEHEECCCCCEE
AMLLDAENTSTEEAVNNYIANNRNQIDYWMNGTMQEPKDREAKP
EEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7622480; 8969502; 9384377 [H]