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The map label for this gene is secF [H]

Identifier: 124023325

GI number: 124023325

Start: 1422549

End: 1423628

Strand: Direct

Name: secF [H]

Synonym: P9303_16231

Alternate gene names: 124023325

Gene position: 1422549-1423628 (Clockwise)

Preceding gene: 124023324

Following gene: 124023326

Centisome position: 53.03

GC content: 55.37

Gene sequence:

>1080_bases
ATGGCTGTTTCATCATCTTCAGGAACTCCTCAACGCCCACTGAGATTTGAACTTTGTCGTCAACGACGACGCGTTTGGGG
AGTCTCAGGCCTGTTTGTGGTTTTCAGCTTGGTGGGCTTGATCCTCTGTTGGCTAAACCCTTCGATTGGGGCTCCCCTTC
GTCCAGGACTTGACTTCACTGGAGGAACTCAAATCCAGCTGGAGCGCAGCTGTAGCAAGAGCTGTCAGTCGCTGAAAACC
AAAAGTGTTGAAGAGGTTTTGGGGGCTCTTGAGTTACCCGCTGACAAAGACAAGGTTGCTCCAAACCTCTCCCGAGCCAG
GGTTCAACTTCTTGATGGTGGTCAGTCTCTGGTCTTGAGGTTGCCCTTCCTCTCTGCGGCTCAGGGGCAGGCTGTCATCA
AGGCAATGGATCCTGTAGCGGGTCCGTTTCAGAGTGGTGGTCAATCGGTCGACACCATTGGCCCAAGTCTGGGAGGCCAA
TTGCTGCGCAGCAGCTTGATTTCTCTTTTGGTGGCGTTCACGGGAATCGCCATCTACATCAGCCTCCGTTACGACCGTCG
CTATGCCCTTCTGGCCCTTGTGGCCCTTGCCCATGACGTGATCATTGTTTGTGGGATATTCGCTTGGCTGGGCCTGCTGA
TAACGCTTGAGGTGGATAGCCTCTTCGCTGTAGCGCTGCTCACCATTGCCGGCTACTCGGTCAATGACACTGTGGTGGTC
TTTGACCGGATCCGTGAGCGCAGTCGCGAAGATGACTCACTGCCACTGACGGAACAGGTTGATCGTGCCGTATCCGCGAC
CCTCACAAGGACCCTCTACACAAGCGGTACGACCCTGCTGCCTCTGCTCGCTCTGATCCTCTTTGGCGGTGCGACGCTCT
ACTGGTTTGCGGTTGCACTTGCTCTTGGAGTGGTGGTTGGTAGCTGGTCGAGTATTGCTCTAGCCCCTTCATTGTTGAGC
CTCTGGCAAGGCAGTGGTCCTCCGAAAGCTCCTTTATCAGCCCCTGCTGCTTCTCCACAACCGCCGTTGTCTTCCTCCCA
GTCTCCGCTTGAGGGAGAAGATGTGATGTCAGATGGCTGA

Upstream 100 bases:

>100_bases
CACTCGCACTCTGCTGCGTTTTTTGATGGGCTATCAGGCTTTGAGGCGACCTACCAACTTTTTGCCTGCCAAACAGTTGC
CTTCTTCTCTCGCCTGATCC

Downstream 100 bases:

>100_bases
AACGGCACGCTCCCGTGGCCTATCTGGCGATCGTTGGTTGCCCGTTCTTCTTTTGGGTCTGTCTCTCTGGGATTTACGAA
CAGAGTTTCTCTTGCTCTGG

Product: preprotein translocase subunit SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MAVSSSSGTPQRPLRFELCRQRRRVWGVSGLFVVFSLVGLILCWLNPSIGAPLRPGLDFTGGTQIQLERSCSKSCQSLKT
KSVEEVLGALELPADKDKVAPNLSRARVQLLDGGQSLVLRLPFLSAAQGQAVIKAMDPVAGPFQSGGQSVDTIGPSLGGQ
LLRSSLISLLVAFTGIAIYISLRYDRRYALLALVALAHDVIIVCGIFAWLGLLITLEVDSLFAVALLTIAGYSVNDTVVV
FDRIRERSREDDSLPLTEQVDRAVSATLTRTLYTSGTTLLPLLALILFGGATLYWFAVALALGVVVGSWSSIALAPSLLS
LWQGSGPPKAPLSAPAASPQPPLSSSQSPLEGEDVMSDG

Sequences:

>Translated_359_residues
MAVSSSSGTPQRPLRFELCRQRRRVWGVSGLFVVFSLVGLILCWLNPSIGAPLRPGLDFTGGTQIQLERSCSKSCQSLKT
KSVEEVLGALELPADKDKVAPNLSRARVQLLDGGQSLVLRLPFLSAAQGQAVIKAMDPVAGPFQSGGQSVDTIGPSLGGQ
LLRSSLISLLVAFTGIAIYISLRYDRRYALLALVALAHDVIIVCGIFAWLGLLITLEVDSLFAVALLTIAGYSVNDTVVV
FDRIRERSREDDSLPLTEQVDRAVSATLTRTLYTSGTTLLPLLALILFGGATLYWFAVALALGVVVGSWSSIALAPSLLS
LWQGSGPPKAPLSAPAASPQPPLSSSQSPLEGEDVMSDG
>Mature_358_residues
AVSSSSGTPQRPLRFELCRQRRRVWGVSGLFVVFSLVGLILCWLNPSIGAPLRPGLDFTGGTQIQLERSCSKSCQSLKTK
SVEEVLGALELPADKDKVAPNLSRARVQLLDGGQSLVLRLPFLSAAQGQAVIKAMDPVAGPFQSGGQSVDTIGPSLGGQL
LRSSLISLLVAFTGIAIYISLRYDRRYALLALVALAHDVIIVCGIFAWLGLLITLEVDSLFAVALLTIAGYSVNDTVVVF
DRIRERSREDDSLPLTEQVDRAVSATLTRTLYTSGTTLLPLLALILFGGATLYWFAVALALGVVVGSWSSIALAPSLLSL
WQGSGPPKAPLSAPAASPQPPLSSSQSPLEGEDVMSDG

Specific function: Involved in protein export [H]

COG id: COG0341

COG function: function code U; Preprotein translocase subunit SecF

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786610, Length=313, Percent_Identity=30.6709265175719, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 38043; Mature: 37911

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSSSSGTPQRPLRFELCRQRRRVWGVSGLFVVFSLVGLILCWLNPSIGAPLRPGLDFT
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GGTQIQLERSCSKSCQSLKTKSVEEVLGALELPADKDKVAPNLSRARVQLLDGGQSLVLR
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCCCCEEEEE
LPFLSAAQGQAVIKAMDPVAGPFQSGGQSVDTIGPSLGGQLLRSSLISLLVAFTGIAIYI
CCCCCCCCCHHHHHHHCCCCCCHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEE
SLRYDRRYALLALVALAHDVIIVCGIFAWLGLLITLEVDSLFAVALLTIAGYSVNDTVVV
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEH
FDRIRERSREDDSLPLTEQVDRAVSATLTRTLYTSGTTLLPLLALILFGGATLYWFAVAL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHH
ALGVVVGSWSSIALAPSLLSLWQGSGPPKAPLSAPAASPQPPLSSSQSPLEGEDVMSDG
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AVSSSSGTPQRPLRFELCRQRRRVWGVSGLFVVFSLVGLILCWLNPSIGAPLRPGLDFT
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GGTQIQLERSCSKSCQSLKTKSVEEVLGALELPADKDKVAPNLSRARVQLLDGGQSLVLR
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCCCCEEEEE
LPFLSAAQGQAVIKAMDPVAGPFQSGGQSVDTIGPSLGGQLLRSSLISLLVAFTGIAIYI
CCCCCCCCCHHHHHHHCCCCCCHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEE
SLRYDRRYALLALVALAHDVIIVCGIFAWLGLLITLEVDSLFAVALLTIAGYSVNDTVVV
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEH
FDRIRERSREDDSLPLTEQVDRAVSATLTRTLYTSGTTLLPLLALILFGGATLYWFAVAL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHH
ALGVVVGSWSSIALAPSLLSLWQGSGPPKAPLSAPAASPQPPLSSSQSPLEGEDVMSDG
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]