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The map label for this gene is secD [H]

Identifier: 124023324

GI number: 124023324

Start: 1421058

End: 1422545

Strand: Direct

Name: secD [H]

Synonym: P9303_16221

Alternate gene names: 124023324

Gene position: 1421058-1422545 (Clockwise)

Preceding gene: 124023323

Following gene: 124023325

Centisome position: 52.97

GC content: 53.16

Gene sequence:

>1488_bases
ATGGCACGTCAACAAGGCTGGTTTGCGCTCATTCTTGCTCTTGCCATTGCGGCAGGTTCTGTCACTGCAAGCTTTCCGCT
TGAGTTGGGCCTTGATCTTCGTGGTGGCAGTCAGCTCACTCTTGAAGTGCAGCCCGCTGGTGAGATCACTCGCGTGAAAG
CCGAGCAGCTAGAGGCGGTCAAAGCTGTTTTGGATCGTCGCGTCAATGGCTTGGGTGTTGCCGAATCCACACTGCAGACC
ATTGGTGACAATCAACTGGTGTTGCAGCTTCCAGGAGAACAGGATCCCACCAGGGCTGCCAAGGTGCTTGGCGAGACGGC
CTTACTTGAGTTTCGAGCTCAAAAACCTGGCACAGAAGAGGAGGTTCGCGGCCTTCAGCGCCTAAAACGACAGGTAGAGA
GCATTCTCAAGTCCAAGCAGGAGCGTGCGATATCCGGAGAGTCTCCCTCTGATGATGAACTCGATAAACAGCAACTTGTT
GAAGCGCAGCAGGCCTTTGGTTTGCAAGGCAGTGTTGGCAGTGAGATCGAGCAGCTGGAACAGTTAAATGAGAAAGTCAG
CATCAAGATCGCTGAACTCTTCGAGCCCACGTCCTTAACCGGGAAGGATCTAGTTACAGCTGGGCGTCAGCAACAGCAGA
ACGTTCCTGATAGCTGGGAGGTGACACTTAGCTTCAACCGAGAAGGCGGAGATCAATTCGCCGAGCTAACACAATCAATT
GCTGGCACAGGTCGTCTACTTGGCATCGTTCTTGATGGAAGGTCGATCAGTGAAGCCAGCGTCGGGGAACAGTTCAGAGC
CGCTGGCATTACTGGTGGTGCGGCCACGATCAGCGGTAATTTCAATGCTGAAGATGCCCGCGACCTGGAAGTTCAGTTGC
GAGGTGGTTCGTTGCCATTACCAGTAGAAATTCTCGAGGTTCGAACCATTGGTCCCACCCTTGGTGCTGAAAACATTCGC
CGCAGCTTGATCGCAGCGCTCTCTGGTCTCGCCTTGGTGGCTGTTTTCATGGTGGTGGCTTATCGCCTTGCGGGCTTGGT
GGCGGTGTTGGCATTGAGTCTTTATGCCCTGTTCAATCTGGCTATGTATGCTCTGATTCCTGTCATCCTTACCCTGCCTG
GGATTGCTGGTTTCATCCTCAGTATTGGCATGGCAGTGGATGCCAATGTGCTGATCTTTGAGCGTGTCAAAGATGAATTG
CGGCGTGGCAACACCTTGATTCGCTCGATCGAGACTGGATTTTCCCAGGCTTTGTCGTCGATCGTTGACGGCCATCTCAC
CACTCTGATTAGTTGCGCAGCGCTCTTTTTTCTGGGTACGGGTTTGGTTAAAGGTTTTGCCGCCACCCTCGGCATCGGTG
TTGTGCTCAGTTTGTTTACGGCCTTGAGCTGCACTCGCACTCTGCTGCGTTTTTTGATGGGCTATCAGGCTTTGAGGCGA
CCTACCAACTTTTTGCCTGCCAAACAGTTGCCTTCTTCTCTCGCCTGA

Upstream 100 bases:

>100_bases
TCCCACTCCATATAACGGCAAATTGGAGAATTTCACGATCATTCAGCCTCATCAGATTGTTGAAGCGGCTCAGCAGATTG
TTCTTAAGGGGCTTTGATTG

Downstream 100 bases:

>100_bases
TCCATGGCTGTTTCATCATCTTCAGGAACTCCTCAACGCCCACTGAGATTTGAACTTTGTCGTCAACGACGACGCGTTTG
GGGAGTCTCAGGCCTGTTTG

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MARQQGWFALILALAIAAGSVTASFPLELGLDLRGGSQLTLEVQPAGEITRVKAEQLEAVKAVLDRRVNGLGVAESTLQT
IGDNQLVLQLPGEQDPTRAAKVLGETALLEFRAQKPGTEEEVRGLQRLKRQVESILKSKQERAISGESPSDDELDKQQLV
EAQQAFGLQGSVGSEIEQLEQLNEKVSIKIAELFEPTSLTGKDLVTAGRQQQQNVPDSWEVTLSFNREGGDQFAELTQSI
AGTGRLLGIVLDGRSISEASVGEQFRAAGITGGAATISGNFNAEDARDLEVQLRGGSLPLPVEILEVRTIGPTLGAENIR
RSLIAALSGLALVAVFMVVAYRLAGLVAVLALSLYALFNLAMYALIPVILTLPGIAGFILSIGMAVDANVLIFERVKDEL
RRGNTLIRSIETGFSQALSSIVDGHLTTLISCAALFFLGTGLVKGFAATLGIGVVLSLFTALSCTRTLLRFLMGYQALRR
PTNFLPAKQLPSSLA

Sequences:

>Translated_495_residues
MARQQGWFALILALAIAAGSVTASFPLELGLDLRGGSQLTLEVQPAGEITRVKAEQLEAVKAVLDRRVNGLGVAESTLQT
IGDNQLVLQLPGEQDPTRAAKVLGETALLEFRAQKPGTEEEVRGLQRLKRQVESILKSKQERAISGESPSDDELDKQQLV
EAQQAFGLQGSVGSEIEQLEQLNEKVSIKIAELFEPTSLTGKDLVTAGRQQQQNVPDSWEVTLSFNREGGDQFAELTQSI
AGTGRLLGIVLDGRSISEASVGEQFRAAGITGGAATISGNFNAEDARDLEVQLRGGSLPLPVEILEVRTIGPTLGAENIR
RSLIAALSGLALVAVFMVVAYRLAGLVAVLALSLYALFNLAMYALIPVILTLPGIAGFILSIGMAVDANVLIFERVKDEL
RRGNTLIRSIETGFSQALSSIVDGHLTTLISCAALFFLGTGLVKGFAATLGIGVVLSLFTALSCTRTLLRFLMGYQALRR
PTNFLPAKQLPSSLA
>Mature_494_residues
ARQQGWFALILALAIAAGSVTASFPLELGLDLRGGSQLTLEVQPAGEITRVKAEQLEAVKAVLDRRVNGLGVAESTLQTI
GDNQLVLQLPGEQDPTRAAKVLGETALLEFRAQKPGTEEEVRGLQRLKRQVESILKSKQERAISGESPSDDELDKQQLVE
AQQAFGLQGSVGSEIEQLEQLNEKVSIKIAELFEPTSLTGKDLVTAGRQQQQNVPDSWEVTLSFNREGGDQFAELTQSIA
GTGRLLGIVLDGRSISEASVGEQFRAAGITGGAATISGNFNAEDARDLEVQLRGGSLPLPVEILEVRTIGPTLGAENIRR
SLIAALSGLALVAVFMVVAYRLAGLVAVLALSLYALFNLAMYALIPVILTLPGIAGFILSIGMAVDANVLIFERVKDELR
RGNTLIRSIETGFSQALSSIVDGHLTTLISCAALFFLGTGLVKGFAATLGIGVVLSLFTALSCTRTLLRFLMGYQALRRP
TNFLPAKQLPSSLA

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=443, Percent_Identity=33.1828442437923, Blast_Score=211, Evalue=9e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 52772; Mature: 52640

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARQQGWFALILALAIAAGSVTASFPLELGLDLRGGSQLTLEVQPAGEITRVKAEQLEAV
CCCCCHHHHHHHHHHHHHCCCCEECCCEECCEECCCCEEEEEECCCCCHHHHHHHHHHHH
KAVLDRRVNGLGVAESTLQTIGDNQLVLQLPGEQDPTRAAKVLGETALLEFRAQKPGTEE
HHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
EVRGLQRLKRQVESILKSKQERAISGESPSDDELDKQQLVEAQQAFGLQGSVGSEIEQLE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QLNEKVSIKIAELFEPTSLTGKDLVTAGRQQQQNVPDSWEVTLSFNREGGDQFAELTQSI
HHHHHHEEEHHHHCCCCCCCCHHHHHCCHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHH
AGTGRLLGIVLDGRSISEASVGEQFRAAGITGGAATISGNFNAEDARDLEVQLRGGSLPL
HCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCC
PVEILEVRTIGPTLGAENIRRSLIAALSGLALVAVFMVVAYRLAGLVAVLALSLYALFNL
CHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMYALIPVILTLPGIAGFILSIGMAVDANVLIFERVKDELRRGNTLIRSIETGFSQALSS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
IVDGHLTTLISCAALFFLGTGLVKGFAATLGIGVVLSLFTALSCTRTLLRFLMGYQALRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTNFLPAKQLPSSLA
CCCCCCHHHCCCCCC
>Mature Secondary Structure 
ARQQGWFALILALAIAAGSVTASFPLELGLDLRGGSQLTLEVQPAGEITRVKAEQLEAV
CCCCHHHHHHHHHHHHHCCCCEECCCEECCEECCCCEEEEEECCCCCHHHHHHHHHHHH
KAVLDRRVNGLGVAESTLQTIGDNQLVLQLPGEQDPTRAAKVLGETALLEFRAQKPGTEE
HHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
EVRGLQRLKRQVESILKSKQERAISGESPSDDELDKQQLVEAQQAFGLQGSVGSEIEQLE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QLNEKVSIKIAELFEPTSLTGKDLVTAGRQQQQNVPDSWEVTLSFNREGGDQFAELTQSI
HHHHHHEEEHHHHCCCCCCCCHHHHHCCHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHH
AGTGRLLGIVLDGRSISEASVGEQFRAAGITGGAATISGNFNAEDARDLEVQLRGGSLPL
HCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCC
PVEILEVRTIGPTLGAENIRRSLIAALSGLALVAVFMVVAYRLAGLVAVLALSLYALFNL
CHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMYALIPVILTLPGIAGFILSIGMAVDANVLIFERVKDELRRGNTLIRSIETGFSQALSS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
IVDGHLTTLISCAALFFLGTGLVKGFAATLGIGVVLSLFTALSCTRTLLRFLMGYQALRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTNFLPAKQLPSSLA
CCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]