The gene/protein map for NC_009614 is currently unavailable.
Definition Prochlorococcus marinus str. MIT 9303, complete genome.
Accession NC_008820
Length 2,682,675

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The map label for this gene is rot [H]

Identifier: 124023216

GI number: 124023216

Start: 1318104

End: 1318532

Strand: Reverse

Name: rot [H]

Synonym: P9303_15141

Alternate gene names: 124023216

Gene position: 1318532-1318104 (Counterclockwise)

Preceding gene: 124023217

Following gene: 124023214

Centisome position: 49.15

GC content: 44.99

Gene sequence:

>429_bases
ATGGACACTGATGCTGGTTTGATTGAGTTGGAGCTCTTTGATGATGATGCTCCCAATACGGTTGCCAATTTCACAAAGCT
GGTTAAAGAGGGTTTTTATGATGGTCTGTCTTTCCATCGTGTGATCGATGGTTTCATGGCTCAAGGTGGCTGCCCAAATA
CACGTGAGGGAGCAAAGGGGATGCCTGGAACCGGTGGACCTGGCTATACGATTAATTGTGAAATAAATAGCAAAAAGCAT
CTTGCCGGTTCTCTTTCTATGGCTCATGCAGGAAAGAACACTGGTGGAAGTCAATTCTTTCTTGTCCATGATGCTCAGCC
ACATCTCGATGGTGTGCATACCGTTTTTGGTCAGGCTGCCAACATCGATGTGGTCTTAGCCTTAAAGAATGGCTCTAGGA
TCAATAAAGTAACCATTCAAGAGGATTGA

Upstream 100 bases:

>100_bases
TCTATTGCTTTGATTTAATTAATATTTCTAGAGATGTCGCGAAATTTGGCTTCACTGACTAGACTAATTTTTTGAGCATC
CTGTTGTGACCAAGGCCCTG

Downstream 100 bases:

>100_bases
AAATATATAGTTGGACTCTTTCACGACCAAAGGATCAGATTGGGAAGGCTCCAGGCATCCCAATCTTTTAGTGGGGAAAA
ATCATCTTTAAATAGTGATG

Product: cyclophilin-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MDTDAGLIELELFDDDAPNTVANFTKLVKEGFYDGLSFHRVIDGFMAQGGCPNTREGAKGMPGTGGPGYTINCEINSKKH
LAGSLSMAHAGKNTGGSQFFLVHDAQPHLDGVHTVFGQAANIDVVLALKNGSRINKVTIQED

Sequences:

>Translated_142_residues
MDTDAGLIELELFDDDAPNTVANFTKLVKEGFYDGLSFHRVIDGFMAQGGCPNTREGAKGMPGTGGPGYTINCEINSKKH
LAGSLSMAHAGKNTGGSQFFLVHDAQPHLDGVHTVFGQAANIDVVLALKNGSRINKVTIQED
>Mature_142_residues
MDTDAGLIELELFDDDAPNTVANFTKLVKEGFYDGLSFHRVIDGFMAQGGCPNTREGAKGMPGTGGPGYTINCEINSKKH
LAGSLSMAHAGKNTGGSQFFLVHDAQPHLDGVHTVFGQAANIDVVLALKNGSRINKVTIQED

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706339, Length=121, Percent_Identity=39.6694214876033, Blast_Score=87, Evalue=5e-18,
Organism=Homo sapiens, GI19557636, Length=141, Percent_Identity=36.1702127659575, Blast_Score=86, Evalue=9e-18,
Organism=Homo sapiens, GI24308049, Length=131, Percent_Identity=40.4580152671756, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI64276486, Length=144, Percent_Identity=36.1111111111111, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI10863927, Length=149, Percent_Identity=41.6107382550336, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI4826932, Length=137, Percent_Identity=40.8759124087591, Blast_Score=78, Evalue=3e-15,
Organism=Homo sapiens, GI6631100, Length=123, Percent_Identity=41.4634146341463, Blast_Score=77, Evalue=3e-15,
Organism=Homo sapiens, GI256017253, Length=146, Percent_Identity=39.041095890411, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI221139811, Length=146, Percent_Identity=39.041095890411, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI256017251, Length=146, Percent_Identity=39.041095890411, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI4505991, Length=124, Percent_Identity=41.9354838709677, Blast_Score=73, Evalue=6e-14,
Organism=Homo sapiens, GI209417936, Length=146, Percent_Identity=38.3561643835616, Blast_Score=73, Evalue=7e-14,
Organism=Homo sapiens, GI30102944, Length=146, Percent_Identity=38.3561643835616, Blast_Score=73, Evalue=7e-14,
Organism=Homo sapiens, GI219842199, Length=146, Percent_Identity=38.3561643835616, Blast_Score=73, Evalue=7e-14,
Organism=Homo sapiens, GI42560244, Length=138, Percent_Identity=37.6811594202899, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI178057341, Length=152, Percent_Identity=38.1578947368421, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI5031987, Length=158, Percent_Identity=38.6075949367089, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI303305009, Length=150, Percent_Identity=40, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI5174637, Length=148, Percent_Identity=40.5405405405405, Blast_Score=71, Evalue=3e-13,
Organism=Homo sapiens, GI310129267, Length=139, Percent_Identity=39.568345323741, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI310120620, Length=139, Percent_Identity=39.568345323741, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI45439316, Length=134, Percent_Identity=41.044776119403, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI310110104, Length=146, Percent_Identity=37.6712328767123, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI4758950, Length=121, Percent_Identity=40.495867768595, Blast_Score=70, Evalue=8e-13,
Organism=Homo sapiens, GI22547212, Length=131, Percent_Identity=35.1145038167939, Blast_Score=68, Evalue=3e-12,
Organism=Homo sapiens, GI7657473, Length=131, Percent_Identity=35.1145038167939, Blast_Score=68, Evalue=3e-12,
Organism=Homo sapiens, GI22547215, Length=131, Percent_Identity=35.1145038167939, Blast_Score=68, Evalue=3e-12,
Organism=Homo sapiens, GI150418007, Length=146, Percent_Identity=35.6164383561644, Blast_Score=66, Evalue=8e-12,
Organism=Homo sapiens, GI5454154, Length=135, Percent_Identity=36.2962962962963, Blast_Score=65, Evalue=1e-11,
Organism=Homo sapiens, GI169164185, Length=143, Percent_Identity=36.3636363636364, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI169163623, Length=143, Percent_Identity=36.3636363636364, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI169163387, Length=143, Percent_Identity=36.3636363636364, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789763, Length=139, Percent_Identity=36.6906474820144, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI1786736, Length=102, Percent_Identity=39.2156862745098, Blast_Score=64, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17539496, Length=122, Percent_Identity=46.7213114754098, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71980594, Length=120, Percent_Identity=39.1666666666667, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71980590, Length=122, Percent_Identity=38.5245901639344, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71997782, Length=122, Percent_Identity=38.5245901639344, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17506311, Length=143, Percent_Identity=39.8601398601399, Blast_Score=76, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17506307, Length=134, Percent_Identity=40.2985074626866, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17532641, Length=123, Percent_Identity=37.3983739837398, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559074, Length=148, Percent_Identity=41.2162162162162, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551282, Length=136, Percent_Identity=38.2352941176471, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17551284, Length=136, Percent_Identity=38.2352941176471, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565860, Length=142, Percent_Identity=40.1408450704225, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17552782, Length=140, Percent_Identity=39.2857142857143, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17539498, Length=119, Percent_Identity=42.8571428571429, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17552780, Length=130, Percent_Identity=39.2307692307692, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17566266, Length=144, Percent_Identity=39.5833333333333, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17552784, Length=124, Percent_Identity=35.4838709677419, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532643, Length=123, Percent_Identity=39.0243902439024, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323562, Length=133, Percent_Identity=42.8571428571429, Blast_Score=84, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320510, Length=135, Percent_Identity=40, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320359, Length=131, Percent_Identity=41.2213740458015, Blast_Score=74, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6321848, Length=138, Percent_Identity=39.8550724637681, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323246, Length=131, Percent_Identity=39.6946564885496, Blast_Score=65, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19922376, Length=143, Percent_Identity=37.7622377622378, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17986117, Length=126, Percent_Identity=40.4761904761905, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24650807, Length=125, Percent_Identity=44, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI20130249, Length=133, Percent_Identity=41.3533834586466, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922912, Length=132, Percent_Identity=38.6363636363636, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357249, Length=123, Percent_Identity=35.7723577235772, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17647301, Length=147, Percent_Identity=38.7755102040816, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24664125, Length=146, Percent_Identity=39.041095890411, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21357783, Length=146, Percent_Identity=39.041095890411, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24652460, Length=119, Percent_Identity=36.9747899159664, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45549139, Length=130, Percent_Identity=41.5384615384615, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24586038, Length=136, Percent_Identity=38.2352941176471, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17136360, Length=131, Percent_Identity=33.587786259542, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15062; Mature: 15062

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MDTDAGLIELELFDDDAPNTVANFTKLVKEGFYDGLSFHRVIDGFMAQGGCPNTREGAKG
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
MPGTGGPGYTINCEINSKKHLAGSLSMAHAGKNTGGSQFFLVHDAQPHLDGVHTVFGQAA
CCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCC
NIDVVLALKNGSRINKVTIQED
CEEEEEEECCCCEEEEEEEECC
>Mature Secondary Structure
MDTDAGLIELELFDDDAPNTVANFTKLVKEGFYDGLSFHRVIDGFMAQGGCPNTREGAKG
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
MPGTGGPGYTINCEINSKKHLAGSLSMAHAGKNTGGSQFFLVHDAQPHLDGVHTVFGQAA
CCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCC
NIDVVLALKNGSRINKVTIQED
CEEEEEEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA