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The map label for this gene is murQ

Identifier: 124023217

GI number: 124023217

Start: 1318799

End: 1319749

Strand: Reverse

Name: murQ

Synonym: P9303_15151

Alternate gene names: 124023217

Gene position: 1319749-1318799 (Counterclockwise)

Preceding gene: 124023218

Following gene: 124023216

Centisome position: 49.2

GC content: 48.9

Gene sequence:

>951_bases
ATGACCAATTTATTTGAACATATAAATTTGCACCCTTCAGATGATCGAGGGCATCTGTTGACTGAACAGGTCAATCCCAA
AAGTGAATGCTTGGATCAACTAAGCACAGAGTCCTTAGTGACACTCTTCTGCGAAGAGGACCGAGAGCCACAGCGTGCCG
TCGCAGCGGCTATACCCGAACTTATTCAGGCAGTTGAAGCGATTACGGACCGGCTTCGAAGCGGAGGCCGCCTTTTTTAT
TTGGGTGCTGGCACCTCAGGGCGACTAGGAGTTCTTGACGCTGCAGAGTGCCCACCAACCTTTTGCAGCGATCCTGATCT
TGTTCAGGGGGTTCTTGCTGGTGGGAGCTCAGCTTTGCTGAAAAGTTCCGAAGGACTTGAAGACATTGAACAGGCAGGGC
AAAAGGATCTTCAGCAGCGTGGCTTTAGCTCTGCTGATTGTCTTGTCGGTATTGCGGCGGGAGGAACGACTCCTTATGTC
AAAGGAGGACTTGCCTACGCAAAGGAAATCAATGCTTTGGCGATTGCAATTTCATGTGTGCCTATAGAACAAGCTGAGTT
GCCATGCAGCATCGATATTCGTCTTTTGACTGGCCCTGAATTACTAACAGGTTCCACGCGCTTGAAGGCCGGTACCGCAA
CAAAGATGGCTCTAAATATTCTTTCAACCTGTGCGATGGTTCGTCTTGGCAAAGTCTTTGGTAATCGCATGGTTGATGTT
GCGGCTACCAACATCAAGCTGATGGATCGTGCCTTGCGAATCCTGCATGATTTAGCTGATGTTGATCGAGATCGTGGAAG
TGAGTTGCTTCAAGCAAGCGATGGCTCTGTAAAAGTGGCTCTGCTGATGCATGCTTGCGGTTTAGATGCTGAGGCTGCCC
AGAAACTCCTGATAGAGCAAAACAATCAATTGCGAACAGCTTTGGCGAGTTGTGGCAATTGCATATCTTGA

Upstream 100 bases:

>100_bases
ATGAGGATCGTTCCGTTGCAGACAGCAATGGATTGGATCAGCAAGTTGAATCAACAGATCTTGAAGAGATTCGCAAGCGG
CTTGAAGGGTTGATTTAACC

Downstream 100 bases:

>100_bases
TTTTAATTGTGCCTTTCCTAAATGAAGACAATAAGATTATTCTACTCGGTAAGTTCACGATAGCAATAACAGATTCGAAG
CGCATGGAATATCCTTAAGT

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTNLFEHINLHPSDDRGHLLTEQVNPKSECLDQLSTESLVTLFCEEDREPQRAVAAAIPELIQAVEAITDRLRSGGRLFY
LGAGTSGRLGVLDAAECPPTFCSDPDLVQGVLAGGSSALLKSSEGLEDIEQAGQKDLQQRGFSSADCLVGIAAGGTTPYV
KGGLAYAKEINALAIAISCVPIEQAELPCSIDIRLLTGPELLTGSTRLKAGTATKMALNILSTCAMVRLGKVFGNRMVDV
AATNIKLMDRALRILHDLADVDRDRGSELLQASDGSVKVALLMHACGLDAEAAQKLLIEQNNQLRTALASCGNCIS

Sequences:

>Translated_316_residues
MTNLFEHINLHPSDDRGHLLTEQVNPKSECLDQLSTESLVTLFCEEDREPQRAVAAAIPELIQAVEAITDRLRSGGRLFY
LGAGTSGRLGVLDAAECPPTFCSDPDLVQGVLAGGSSALLKSSEGLEDIEQAGQKDLQQRGFSSADCLVGIAAGGTTPYV
KGGLAYAKEINALAIAISCVPIEQAELPCSIDIRLLTGPELLTGSTRLKAGTATKMALNILSTCAMVRLGKVFGNRMVDV
AATNIKLMDRALRILHDLADVDRDRGSELLQASDGSVKVALLMHACGLDAEAAQKLLIEQNNQLRTALASCGNCIS
>Mature_315_residues
TNLFEHINLHPSDDRGHLLTEQVNPKSECLDQLSTESLVTLFCEEDREPQRAVAAAIPELIQAVEAITDRLRSGGRLFYL
GAGTSGRLGVLDAAECPPTFCSDPDLVQGVLAGGSSALLKSSEGLEDIEQAGQKDLQQRGFSSADCLVGIAAGGTTPYVK
GGLAYAKEINALAIAISCVPIEQAELPCSIDIRLLTGPELLTGSTRLKAGTATKMALNILSTCAMVRLGKVFGNRMVDVA
ATNIKLMDRALRILHDLADVDRDRGSELLQASDGSVKVALLMHACGLDAEAAQKLLIEQNNQLRTALASCGNCIS

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=290, Percent_Identity=41.3793103448276, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_PROM3 (A2C9U9)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001017524.1
- ProteinModelPortal:   A2C9U9
- SMR:   A2C9U9
- STRING:   A2C9U9
- GeneID:   4777047
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_15151
- eggNOG:   COG2103
- HOGENOM:   HBG703490
- OMA:   SMIGVGK
- ProtClustDB:   PRK05441
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- TIGRFAMs:   TIGR00274

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 33457; Mature: 33325

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 96-96 ACT_SITE 127-127

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLFEHINLHPSDDRGHLLTEQVNPKSECLDQLSTESLVTLFCEEDREPQRAVAAAIPE
CCCCHHHCCCCCCCCCCCEECCCCCCHHHHHHHHCHHHHHHHEECCCCCHHHHHHHHHHH
LIQAVEAITDRLRSGGRLFYLGAGTSGRLGVLDAAECPPTFCSDPDLVQGVLAGGSSALL
HHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCHHHH
KSSEGLEDIEQAGQKDLQQRGFSSADCLVGIAAGGTTPYVKGGLAYAKEINALAIAISCV
HCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHCCCHHHHHHCCEEEEEEEEE
PIEQAELPCSIDIRLLTGPELLTGSTRLKAGTATKMALNILSTCAMVRLGKVFGNRMVDV
ECCCCCCCCEEEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEH
AATNIKLMDRALRILHDLADVDRDRGSELLQASDGSVKVALLMHACGLDAEAAQKLLIEQ
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEHHHHHHCCCHHHHHHHHHHC
NNQLRTALASCGNCIS
CCHHHHHHHHCCCCCC
>Mature Secondary Structure 
TNLFEHINLHPSDDRGHLLTEQVNPKSECLDQLSTESLVTLFCEEDREPQRAVAAAIPE
CCCHHHCCCCCCCCCCCEECCCCCCHHHHHHHHCHHHHHHHEECCCCCHHHHHHHHHHH
LIQAVEAITDRLRSGGRLFYLGAGTSGRLGVLDAAECPPTFCSDPDLVQGVLAGGSSALL
HHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCHHHH
KSSEGLEDIEQAGQKDLQQRGFSSADCLVGIAAGGTTPYVKGGLAYAKEINALAIAISCV
HCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHCCCHHHHHHCCEEEEEEEEE
PIEQAELPCSIDIRLLTGPELLTGSTRLKAGTATKMALNILSTCAMVRLGKVFGNRMVDV
ECCCCCCCCEEEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEH
AATNIKLMDRALRILHDLADVDRDRGSELLQASDGSVKVALLMHACGLDAEAAQKLLIEQ
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEHHHHHHCCCHHHHHHHHHHC
NNQLRTALASCGNCIS
CCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA