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The map label for this gene is tldD [C]

Identifier: 124023146

GI number: 124023146

Start: 1240863

End: 1242308

Strand: Reverse

Name: tldD [C]

Synonym: P9303_14421

Alternate gene names: 124023146

Gene position: 1242308-1240863 (Counterclockwise)

Preceding gene: 124023147

Following gene: 124023145

Centisome position: 46.31

GC content: 52.9

Gene sequence:

>1446_bases
TTGGTCTCGACCTACACCCCAGATCAAAGCCTGGTGCACAAGGCAGAAGCCTTGAATAGCCACTGGCAACCACAACTGGA
ATTTCTACTAGCGCGTGGTCGAACTGCCGGTGCTGATCTAGTGGAGGTCTACCTGGAGCAAATTGATCATCTCAGCGTCC
TAGCTGAACAAGACACCATTACCAGTGTCAATCCATCCTTCGGTAGGGGGGCTGGGATCAGGGTGTTCCTGGGCAAACAA
GATGGCTTTGTCAGTACCAATGATCTTTCAGATGCAGGCCTGAAACATGCATTAGAGCAAGCTCTCAGCATGCTTGGGCT
TGAGGTTAATGAGGCTGTTCACTCATCATTTGATGGTCTTCCGAATCTTCGTGATTTCGCCATCGATAAGGCCCACTGGC
TCAACCAATGCCCAGAGCTGTATGAAGCAAGTGATCGCCTTTTAAATGGGACTCAATTGCTTGATCAGCACGGAACCCAT
CTTCAGGTGCGCCGAGGCAGTTATGCCCGCGACTGGCAGGAAGTTCTCGTGGCGGCAAGTGATGGCACCTTTGGACGGGA
CATCCGCTTGCATCAGTCCATAGGGCTTAATGTCCTTGCTACAGATGGCGAACACCGCTCAAGCATTGGTCGCCGTTATG
GAACATCGGGACGTCCAGACGACCTTCGAAATTGGGATTCCGAAACGAGCGCCAAGGAAGTTTGCGAAAGCGCAGGCACG
ATGCTTTATGCCGATTACGTGGACGCTGGTCAAATGCCAGCAGTACTCGCCAACCGCTTTGGTGGTGTGATTTTTCACGA
AGCATGTGGTCATTTGCTCGAGACCACTCAGATCGAACGCGGTACAACACCTTTCAGCGACAAGTTGAACCAATCGATCG
CCCATGAAGCTGTAACGGCAATCGATGAGGGGATTACTGATGGGGCCTTCGGTTCCCTGAGCATGGATGACGAAGGCATG
GAAAGTCAGCGAACGGTATTAATTGAAAACGGTGTGCTCAAGCAATTCATCAGCGATAGAGCCGGTGAGCTACGCACCGG
TCACCAACGCACCGGCAGCGGCCGACGTCAGGCCCACACATTCGCTGCAGCTAGCCGCATGCGCAACACTTATATCGCCG
CCGGCCAGCACTCACCGGAACAACTCATCGCCTCAATCGACCGAGGCCTTTACTGCAAATCAATGGGTGGAGGGAGCGTT
GGACCCACGGGTCAATTTAATTTTGCCGTGGAAGAGGGCTATCTGATCGAGAAAGGCAAGCTCGGCAAGCCTGTTAAAGG
AGCCACTCTGATTGGCGAAGCAAAGGATGTGATGCCACGGATTTCTATGTGTGCCAAGGATCTTGAGCTGGCAGCCGGTT
TCTGCGGGTCAATAAGCGGCAACATTTTTGTCACCGTAGGGCAGCCACATATCAAAGTCGATTCAATTACCGTGGGAGGC
CGCTGA

Upstream 100 bases:

>100_bases
GAAATAAGCATTTTTTTTGCGGTTCGCCTGGATCGGCGCTGTCCATCTACATATCTACGCAAATTCTCTCCATAATCAAC
GCAAGCTGCAGGAGAAATGG

Downstream 100 bases:

>100_bases
TTATGTCCGAAATAAAAAGAGCAAATGCAATCGAACTCGATACTCATTCCCTACGGGACAAGCTCAGTCAACTTGCTAGC
CGCGAGAGTATCCACCAATG

Product: modulator of DNA gyrase; TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MVSTYTPDQSLVHKAEALNSHWQPQLEFLLARGRTAGADLVEVYLEQIDHLSVLAEQDTITSVNPSFGRGAGIRVFLGKQ
DGFVSTNDLSDAGLKHALEQALSMLGLEVNEAVHSSFDGLPNLRDFAIDKAHWLNQCPELYEASDRLLNGTQLLDQHGTH
LQVRRGSYARDWQEVLVAASDGTFGRDIRLHQSIGLNVLATDGEHRSSIGRRYGTSGRPDDLRNWDSETSAKEVCESAGT
MLYADYVDAGQMPAVLANRFGGVIFHEACGHLLETTQIERGTTPFSDKLNQSIAHEAVTAIDEGITDGAFGSLSMDDEGM
ESQRTVLIENGVLKQFISDRAGELRTGHQRTGSGRRQAHTFAAASRMRNTYIAAGQHSPEQLIASIDRGLYCKSMGGGSV
GPTGQFNFAVEEGYLIEKGKLGKPVKGATLIGEAKDVMPRISMCAKDLELAAGFCGSISGNIFVTVGQPHIKVDSITVGG
R

Sequences:

>Translated_481_residues
MVSTYTPDQSLVHKAEALNSHWQPQLEFLLARGRTAGADLVEVYLEQIDHLSVLAEQDTITSVNPSFGRGAGIRVFLGKQ
DGFVSTNDLSDAGLKHALEQALSMLGLEVNEAVHSSFDGLPNLRDFAIDKAHWLNQCPELYEASDRLLNGTQLLDQHGTH
LQVRRGSYARDWQEVLVAASDGTFGRDIRLHQSIGLNVLATDGEHRSSIGRRYGTSGRPDDLRNWDSETSAKEVCESAGT
MLYADYVDAGQMPAVLANRFGGVIFHEACGHLLETTQIERGTTPFSDKLNQSIAHEAVTAIDEGITDGAFGSLSMDDEGM
ESQRTVLIENGVLKQFISDRAGELRTGHQRTGSGRRQAHTFAAASRMRNTYIAAGQHSPEQLIASIDRGLYCKSMGGGSV
GPTGQFNFAVEEGYLIEKGKLGKPVKGATLIGEAKDVMPRISMCAKDLELAAGFCGSISGNIFVTVGQPHIKVDSITVGG
R
>Mature_481_residues
MVSTYTPDQSLVHKAEALNSHWQPQLEFLLARGRTAGADLVEVYLEQIDHLSVLAEQDTITSVNPSFGRGAGIRVFLGKQ
DGFVSTNDLSDAGLKHALEQALSMLGLEVNEAVHSSFDGLPNLRDFAIDKAHWLNQCPELYEASDRLLNGTQLLDQHGTH
LQVRRGSYARDWQEVLVAASDGTFGRDIRLHQSIGLNVLATDGEHRSSIGRRYGTSGRPDDLRNWDSETSAKEVCESAGT
MLYADYVDAGQMPAVLANRFGGVIFHEACGHLLETTQIERGTTPFSDKLNQSIAHEAVTAIDEGITDGAFGSLSMDDEGM
ESQRTVLIENGVLKQFISDRAGELRTGHQRTGSGRRQAHTFAAASRMRNTYIAAGQHSPEQLIASIDRGLYCKSMGGGSV
GPTGQFNFAVEEGYLIEKGKLGKPVKGATLIGEAKDVMPRISMCAKDLELAAGFCGSISGNIFVTVGQPHIKVDSITVGG
R

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=462, Percent_Identity=33.7662337662338, Blast_Score=222, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 52031; Mature: 52031

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTYTPDQSLVHKAEALNSHWQPQLEFLLARGRTAGADLVEVYLEQIDHLSVLAEQDTI
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
TSVNPSFGRGAGIRVFLGKQDGFVSTNDLSDAGLKHALEQALSMLGLEVNEAVHSSFDGL
CCCCCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PNLRDFAIDKAHWLNQCPELYEASDRLLNGTQLLDQHGTHLQVRRGSYARDWQEVLVAAS
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHEEECC
DGTFGRDIRLHQSIGLNVLATDGEHRSSIGRRYGTSGRPDDLRNWDSETSAKEVCESAGT
CCCCCCCEEEECCCCCEEEECCCHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHCCC
MLYADYVDAGQMPAVLANRFGGVIFHEACGHLLETTQIERGTTPFSDKLNQSIAHEAVTA
EEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IDEGITDGAFGSLSMDDEGMESQRTVLIENGVLKQFISDRAGELRTGHQRTGSGRRQAHT
HHCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
FAAASRMRNTYIAAGQHSPEQLIASIDRGLYCKSMGGGSVGPTGQFNFAVEEGYLIEKGK
HHHHHHHCCCEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEECCCEEEECCC
LGKPVKGATLIGEAKDVMPRISMCAKDLELAAGFCGSISGNIFVTVGQPHIKVDSITVGG
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEECCC
R
C
>Mature Secondary Structure
MVSTYTPDQSLVHKAEALNSHWQPQLEFLLARGRTAGADLVEVYLEQIDHLSVLAEQDTI
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
TSVNPSFGRGAGIRVFLGKQDGFVSTNDLSDAGLKHALEQALSMLGLEVNEAVHSSFDGL
CCCCCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PNLRDFAIDKAHWLNQCPELYEASDRLLNGTQLLDQHGTHLQVRRGSYARDWQEVLVAAS
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHEEECC
DGTFGRDIRLHQSIGLNVLATDGEHRSSIGRRYGTSGRPDDLRNWDSETSAKEVCESAGT
CCCCCCCEEEECCCCCEEEECCCHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHCCC
MLYADYVDAGQMPAVLANRFGGVIFHEACGHLLETTQIERGTTPFSDKLNQSIAHEAVTA
EEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IDEGITDGAFGSLSMDDEGMESQRTVLIENGVLKQFISDRAGELRTGHQRTGSGRRQAHT
HHCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
FAAASRMRNTYIAAGQHSPEQLIASIDRGLYCKSMGGGSVGPTGQFNFAVEEGYLIEKGK
HHHHHHHCCCEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEECCCEEEECCC
LGKPVKGATLIGEAKDVMPRISMCAKDLELAAGFCGSISGNIFVTVGQPHIKVDSITVGG
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEECCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]