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The map label for this gene is rsuA [C]

Identifier: 124022690

GI number: 124022690

Start: 892529

End: 893263

Strand: Reverse

Name: rsuA [C]

Synonym: P9303_09831

Alternate gene names: 124022690

Gene position: 893263-892529 (Counterclockwise)

Preceding gene: 124022692

Following gene: 124022687

Centisome position: 33.3

GC content: 53.06

Gene sequence:

>735_bases
ATGAAGCAACAAAGACTGCAGAAACTGATTGCAGCGTCAGGACTCTGCTCCCGGCGCCATGCAGAGCAACTCCTCCTGCA
AGAGCGGGTAACGTTGAATGGCCATCTTGCCAAGCTTGGCGACAAGGCCGATCCAGAGCTTGACAAGATCTCTGTAGATG
GGCGTGTGCTCAATTCCAACACCGAAACAAGAGTGTTGCTGTTCAACAAACCTGCGGGGGTTATCACTAGTTGTCATGAT
CCCCACGGGCGAGTGACTGTCTTCAGCCTGCTGCCCGACAAACTATGCAAGGGTCTTCATCCTGTAGGCAGACTTGATGC
CGATAGCCGAGGAGCTCTGCTAATCACCAACCGAGGAGAGCTCACGCTGCGATTGACCCATCCACGCTATGCACATGACA
AGACTTACCAAGTCTTGGTGGAAGGTAAACCCTCACCCCTAGTGCTCTCAAGCTGGCGGCATGGCGTCATGCTTGATGGG
AAAACAACCTTGCCCGCTGAACTAGAGCTTTTGCAATCACACCCAAGCCAAAGCCTTTTGAAGGTTGTCCTAAGGGAAGG
CCGCAACCGGCAAATCCGTCGCGTAGCAGAACAACTAGGTCACCCCGTATTAGACCTTCAACGCACAGCGATTGCAAATG
TTGCCCTAGACGCATTACCAGAAGGGTGCTGGCGCGCTCTTGACGAGAGAGAATGGACTCCCCTACTGAAAATCACCAAG
CCCTCAATGTGTTGA

Upstream 100 bases:

>100_bases
CCTCACCACATCTTCCAAAACACTCTTCCAACTATTAAATGTTTGGAGATGGTGCAGCTGGTTCTCGGCGCCCGCTGAAA
GCCATGCTGAAAACATTGGC

Downstream 100 bases:

>100_bases
TGCGCTTGATAAAGCCATCCAATTGAAACGCCGATGCGACTAAACCTTCCATGGCAAAAATCAAGATCTGAAGTCGAAAC
CAGACAAGATCCACAACAGA

Product: pseudouridylate synthase specific to ribosomal small subunit

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MKQQRLQKLIAASGLCSRRHAEQLLLQERVTLNGHLAKLGDKADPELDKISVDGRVLNSNTETRVLLFNKPAGVITSCHD
PHGRVTVFSLLPDKLCKGLHPVGRLDADSRGALLITNRGELTLRLTHPRYAHDKTYQVLVEGKPSPLVLSSWRHGVMLDG
KTTLPAELELLQSHPSQSLLKVVLREGRNRQIRRVAEQLGHPVLDLQRTAIANVALDALPEGCWRALDEREWTPLLKITK
PSMC

Sequences:

>Translated_244_residues
MKQQRLQKLIAASGLCSRRHAEQLLLQERVTLNGHLAKLGDKADPELDKISVDGRVLNSNTETRVLLFNKPAGVITSCHD
PHGRVTVFSLLPDKLCKGLHPVGRLDADSRGALLITNRGELTLRLTHPRYAHDKTYQVLVEGKPSPLVLSSWRHGVMLDG
KTTLPAELELLQSHPSQSLLKVVLREGRNRQIRRVAEQLGHPVLDLQRTAIANVALDALPEGCWRALDEREWTPLLKITK
PSMC
>Mature_244_residues
MKQQRLQKLIAASGLCSRRHAEQLLLQERVTLNGHLAKLGDKADPELDKISVDGRVLNSNTETRVLLFNKPAGVITSCHD
PHGRVTVFSLLPDKLCKGLHPVGRLDADSRGALLITNRGELTLRLTHPRYAHDKTYQVLVEGKPSPLVLSSWRHGVMLDG
KTTLPAELELLQSHPSQSLLKVVLREGRNRQIRRVAEQLGHPVLDLQRTAIANVALDALPEGCWRALDEREWTPLLKITK
PSMC

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790453, Length=240, Percent_Identity=33.75, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87081838, Length=186, Percent_Identity=40.8602150537634, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1787524, Length=232, Percent_Identity=35.7758620689655, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788510, Length=231, Percent_Identity=34.1991341991342, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 27210; Mature: 27210

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQQRLQKLIAASGLCSRRHAEQLLLQERVTLNGHLAKLGDKADPELDKISVDGRVLNSN
CCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEEECCEEECCC
TETRVLLFNKPAGVITSCHDPHGRVTVFSLLPDKLCKGLHPVGRLDADSRGALLITNRGE
CCEEEEEEECCCCCEEECCCCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCEEEEECCCC
LTLRLTHPRYAHDKTYQVLVEGKPSPLVLSSWRHGVMLDGKTTLPAELELLQSHPSQSLL
EEEEECCCCCCCCCEEEEEEECCCCCEEEECCCCCEEECCCCCCHHHHHHHHCCCHHHHH
KVVLREGRNRQIRRVAEQLGHPVLDLQRTAIANVALDALPEGCWRALDEREWTPLLKITK
HHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEECC
PSMC
CCCC
>Mature Secondary Structure
MKQQRLQKLIAASGLCSRRHAEQLLLQERVTLNGHLAKLGDKADPELDKISVDGRVLNSN
CCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEEECCEEECCC
TETRVLLFNKPAGVITSCHDPHGRVTVFSLLPDKLCKGLHPVGRLDADSRGALLITNRGE
CCEEEEEEECCCCCEEECCCCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCEEEEECCCC
LTLRLTHPRYAHDKTYQVLVEGKPSPLVLSSWRHGVMLDGKTTLPAELELLQSHPSQSLL
EEEEECCCCCCCCCEEEEEEECCCCCEEEECCCCCEEECCCCCCHHHHHHHHCCCHHHHH
KVVLREGRNRQIRRVAEQLGHPVLDLQRTAIANVALDALPEGCWRALDEREWTPLLKITK
HHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEECC
PSMC
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]