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The map label for this gene is msrR [H]

Identifier: 124022678

GI number: 124022678

Start: 882585

End: 883481

Strand: Direct

Name: msrR [H]

Synonym: P9303_09711

Alternate gene names: 124022678

Gene position: 882585-883481 (Clockwise)

Preceding gene: 124022676

Following gene: 124022680

Centisome position: 32.9

GC content: 47.16

Gene sequence:

>897_bases
ATGACTCCCAAGCATCAAGGCAGTTCTGGTTGGCGTTCAATGACCACTGCCATTGGCGTGGGGCTGATCGCAGGCCTGTT
CCTTTCAATTCCACTCAGTCGATCACTCACACAAAAGACTGCAGGCACAACCACTCCCCTTTTCCCGATTAGCAATCCAT
TCAATGCATGGAAGGGATTTGGTGATCGTGATGTGGTGGTGCTCGGCATGGATGCAGGGCGGGGTAACACTGATGTGATC
TTTACGATTCGAGTTGCGGGGGGCGAAACAAGAATCACCCAGATTCCACGTGATAGTTATATCAATTCGCGTAATTTTGG
GCCAATGAAAGTTAATGCTTTGTATGCATATGGTGGTATAGAGGCAGTAAAAAGTGAGTTGACGCGGCTGATGCATCGTC
CCATTAGCCATCACATCCTTGTTAATCTTGAAGGGATCAGAACTATTGCAGACTTATTGGGAGGCATTGAGGTTGATGTG
CCTAAGCGTCTTTTTTACCAAGATCAATCCCAGGGTCTTTATATTGATCTTCAAGCTGGCCCTCAGGTCTTAAAAGGTAA
AGATCTCGAGGGTTTTTTGCGTTGGCGCCATGATGGTGAAGGCGACTTTGGTCGCCTAGGTCGTCAACAACTAGTCCTCA
AGAGTCTCTTTAGTAAGCTCACTCGAGCTGAGAATCTTGTTCGACTGCCAGCATTGATAAGTGCTGCTGGCCGTAACATC
AAGACAGATATGGGGCCTTTGGAGCTTGGAGGTTTAATGACAGCAATGGGTACCACTGAACTTGAAACAACGCGACTACC
AGCTAAGCCATTCTTTAGTAATGGCATTAGCTACCTAGACACTGAATGGCCAGATGCTGCGGAAGCCAATGGCTCGCTTT
ATCGATTCCTATTTTAA

Upstream 100 bases:

>100_bases
TCTCTAGCCGTTCAACACAATTGAGCATTGGCTGGAGTGTTGCTTAAAGCCGCAGGCTACTTTTATTAGAGAAAAATCTA
AAGGGCTCTAAGATGGTGAT

Downstream 100 bases:

>100_bases
ATCGATCGCTGGCAGATCAAAACCGAATCATTTTCCTTGGGCTATTAATGGGAAATTTTCTATGAAGTGTTTGTTCAACT
TCAACTCCATGATATACAAG

Product: membrane bound transcriptional regulator-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTPKHQGSSGWRSMTTAIGVGLIAGLFLSIPLSRSLTQKTAGTTTPLFPISNPFNAWKGFGDRDVVVLGMDAGRGNTDVI
FTIRVAGGETRITQIPRDSYINSRNFGPMKVNALYAYGGIEAVKSELTRLMHRPISHHILVNLEGIRTIADLLGGIEVDV
PKRLFYQDQSQGLYIDLQAGPQVLKGKDLEGFLRWRHDGEGDFGRLGRQQLVLKSLFSKLTRAENLVRLPALISAAGRNI
KTDMGPLELGGLMTAMGTTELETTRLPAKPFFSNGISYLDTEWPDAAEANGSLYRFLF

Sequences:

>Translated_298_residues
MTPKHQGSSGWRSMTTAIGVGLIAGLFLSIPLSRSLTQKTAGTTTPLFPISNPFNAWKGFGDRDVVVLGMDAGRGNTDVI
FTIRVAGGETRITQIPRDSYINSRNFGPMKVNALYAYGGIEAVKSELTRLMHRPISHHILVNLEGIRTIADLLGGIEVDV
PKRLFYQDQSQGLYIDLQAGPQVLKGKDLEGFLRWRHDGEGDFGRLGRQQLVLKSLFSKLTRAENLVRLPALISAAGRNI
KTDMGPLELGGLMTAMGTTELETTRLPAKPFFSNGISYLDTEWPDAAEANGSLYRFLF
>Mature_297_residues
TPKHQGSSGWRSMTTAIGVGLIAGLFLSIPLSRSLTQKTAGTTTPLFPISNPFNAWKGFGDRDVVVLGMDAGRGNTDVIF
TIRVAGGETRITQIPRDSYINSRNFGPMKVNALYAYGGIEAVKSELTRLMHRPISHHILVNLEGIRTIADLLGGIEVDVP
KRLFYQDQSQGLYIDLQAGPQVLKGKDLEGFLRWRHDGEGDFGRLGRQQLVLKSLFSKLTRAENLVRLPALISAAGRNIK
TDMGPLELGGLMTAMGTTELETTRLPAKPFFSNGISYLDTEWPDAAEANGSLYRFLF

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 32682; Mature: 32551

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPKHQGSSGWRSMTTAIGVGLIAGLFLSIPLSRSLTQKTAGTTTPLFPISNPFNAWKGF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHCCC
GDRDVVVLGMDAGRGNTDVIFTIRVAGGETRITQIPRDSYINSRNFGPMKVNALYAYGGI
CCCCEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCHHCCCCCCCCCEEEEEEEEECCH
EAVKSELTRLMHRPISHHILVNLEGIRTIADLLGGIEVDVPKRLFYQDQSQGLYIDLQAG
HHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCEECCCHHHHHCCCCCCEEEEECCC
PQVLKGKDLEGFLRWRHDGEGDFGRLGRQQLVLKSLFSKLTRAENLVRLPALISAAGRNI
CCCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KTDMGPLELGGLMTAMGTTELETTRLPAKPFFSNGISYLDTEWPDAAEANGSLYRFLF
CCCCCCHHHHHHHHHCCCCCCHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
TPKHQGSSGWRSMTTAIGVGLIAGLFLSIPLSRSLTQKTAGTTTPLFPISNPFNAWKGF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHCCC
GDRDVVVLGMDAGRGNTDVIFTIRVAGGETRITQIPRDSYINSRNFGPMKVNALYAYGGI
CCCCEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCHHCCCCCCCCCEEEEEEEEECCH
EAVKSELTRLMHRPISHHILVNLEGIRTIADLLGGIEVDVPKRLFYQDQSQGLYIDLQAG
HHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCEECCCHHHHHCCCCCCEEEEECCC
PQVLKGKDLEGFLRWRHDGEGDFGRLGRQQLVLKSLFSKLTRAENLVRLPALISAAGRNI
CCCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KTDMGPLELGGLMTAMGTTELETTRLPAKPFFSNGISYLDTEWPDAAEANGSLYRFLF
CCCCCCHHHHHHHHHCCCCCCHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]