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The map label for this gene is cysS [H]

Identifier: 124022576

GI number: 124022576

Start: 784802

End: 786337

Strand: Reverse

Name: cysS [H]

Synonym: P9303_08671

Alternate gene names: 124022576

Gene position: 786337-784802 (Counterclockwise)

Preceding gene: 124022577

Following gene: 124022574

Centisome position: 29.31

GC content: 57.1

Gene sequence:

>1536_bases
GTGGCCCTAGCCTCAAAGCAAGCTCCAGCCCTGCCAGTGTCACTGCGGCTCACAAACACCCTCACCCGCCGCACGGAACC
CTTCACTCCGCTCAAGGACGGGCACGTCAGCATCTACTGCTGCGGCGTCACGGTCTACGACCTCTGCCATCTCGGCCATG
CCCGCAGCTACATCGCCTGGGATGTGCTGCGTCGCTATTTGCTTTGGCGTGGCTACTCAGTCACCTTCGTGCAGAACTTC
ACTGATATCGACGACAAAATCCTCAAGCGTGCCGCTGAAAAGAAATGCTCCATGGAGCACATCAGCGAGCAAAACATCGA
GGCTTTCCATCAAGACATGGATGCCCTAGGCATCCTGCGGCCCGATCGCATGCCCCGCGCCACACAATGCCTAGACGGGA
TACGCGCCTTGATCGGAGAATTAGAAACTAGTGGGGCTGCCTACTCTGTCGATGGCGATGTCTACTTCGCCGTGATGAAA
CATCACGGCTACGGCAAGCTCAGTGGTCGTGATCTCAATGAGCAGCAGCAAAACGCCGATGGTCGTGTGGCCGATGCCGA
AGAGGCGCGCAAACAACACTCCTTTGATTTCGCGCTATGGAAGGGAGCTAAAACCGGAGAGCCAAGCTTTCCCTCACCCT
GGGGAGCTGGCCGCCCAGGGTGGCATATCGAGTGTTCCGCCATGGTGCGCGAGGAATTGGGCGAAACAATCGACATCCAC
CTGGGGGGAGCTGACCTGATCTTCCCTCATCACGAAAACGAGATTGCTCAATCGGAGGCAGCTACGGGCAAGCAGCTTGC
TCGCTATTGGCTACACAACGGCATGGTGAATGTCGGCGGTCAGAAAATGAGCAAGTCACTGGGTAACTTCACCACGATCA
GAGCCCTGCTCGAGAGCGGCGTCTCCCCAATGACACTGCGCCTGTTCATTCTGCAGGCCCATTACCGCAAACCGCTCGAC
TTCACAGCCGATGCCATCAACGCTGCAGCCACCGGATGGAAAGGTCTTAATGCAGCCCTTGGCCTCGGCAACATCTATGC
CGAGGCCCTGAACTGGCCTGAATGCAAACCCCTACCACAAGAAGTCATGCAACCCGCCCATTCCTCCACTCTGGAGCAAT
GCAGCGAAATACGTCAACACTTCATCGATGCACTGGACGATGACCTCAACAGCTCAGGGGCCATCGCCGTACTATTCGAT
CTTGCTCGCCCCCTGCGTGCCCTAGCGAACCGCTTGGAGCGTGGTGACACAAAGGCAATTCAAGAAACAGCGCAGCTGAA
CTTGCTCCCACGTTGGCAACTGCTAGTGGAGCTGGCCAATGTGCTCGGGCTTGAGGCCGAAAAAGCCGCGAAACTGGCCC
CCGAGGGAAACAACAGGGTTGATGAAAACCATATTCAACTCGCTATTGCCGCTCGCAAAGAGGCTAAAGCTGCCCGTGAT
TTCGCCAAAGCCGATCGCATCCGCGACGAGCTGCGCGCCCAAGGCATCGAACTAATCGATAAACCAGGTGGCCTCACAGA
CTGGATCAGCAGCTGA

Upstream 100 bases:

>100_bases
GGCTGGGAGCGGCCACTTGTGCAATGGCGCGAAGAACTAAGGCTTCCGCACACCAACGCGAGCTAAGAATCAGTCTGAGC
CGAACGCAGGTTCAGAACGC

Downstream 100 bases:

>100_bases
TCATCATCCGCGGAACGTTCTGGTTTTCAACCATCAGCGGTTCGATGAGCGACTTCGGCTTCGCCAGCTCTAGGGATACA
AACGCTTCAGCTAAATCGAC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MALASKQAPALPVSLRLTNTLTRRTEPFTPLKDGHVSIYCCGVTVYDLCHLGHARSYIAWDVLRRYLLWRGYSVTFVQNF
TDIDDKILKRAAEKKCSMEHISEQNIEAFHQDMDALGILRPDRMPRATQCLDGIRALIGELETSGAAYSVDGDVYFAVMK
HHGYGKLSGRDLNEQQQNADGRVADAEEARKQHSFDFALWKGAKTGEPSFPSPWGAGRPGWHIECSAMVREELGETIDIH
LGGADLIFPHHENEIAQSEAATGKQLARYWLHNGMVNVGGQKMSKSLGNFTTIRALLESGVSPMTLRLFILQAHYRKPLD
FTADAINAAATGWKGLNAALGLGNIYAEALNWPECKPLPQEVMQPAHSSTLEQCSEIRQHFIDALDDDLNSSGAIAVLFD
LARPLRALANRLERGDTKAIQETAQLNLLPRWQLLVELANVLGLEAEKAAKLAPEGNNRVDENHIQLAIAARKEAKAARD
FAKADRIRDELRAQGIELIDKPGGLTDWISS

Sequences:

>Translated_511_residues
MALASKQAPALPVSLRLTNTLTRRTEPFTPLKDGHVSIYCCGVTVYDLCHLGHARSYIAWDVLRRYLLWRGYSVTFVQNF
TDIDDKILKRAAEKKCSMEHISEQNIEAFHQDMDALGILRPDRMPRATQCLDGIRALIGELETSGAAYSVDGDVYFAVMK
HHGYGKLSGRDLNEQQQNADGRVADAEEARKQHSFDFALWKGAKTGEPSFPSPWGAGRPGWHIECSAMVREELGETIDIH
LGGADLIFPHHENEIAQSEAATGKQLARYWLHNGMVNVGGQKMSKSLGNFTTIRALLESGVSPMTLRLFILQAHYRKPLD
FTADAINAAATGWKGLNAALGLGNIYAEALNWPECKPLPQEVMQPAHSSTLEQCSEIRQHFIDALDDDLNSSGAIAVLFD
LARPLRALANRLERGDTKAIQETAQLNLLPRWQLLVELANVLGLEAEKAAKLAPEGNNRVDENHIQLAIAARKEAKAARD
FAKADRIRDELRAQGIELIDKPGGLTDWISS
>Mature_510_residues
ALASKQAPALPVSLRLTNTLTRRTEPFTPLKDGHVSIYCCGVTVYDLCHLGHARSYIAWDVLRRYLLWRGYSVTFVQNFT
DIDDKILKRAAEKKCSMEHISEQNIEAFHQDMDALGILRPDRMPRATQCLDGIRALIGELETSGAAYSVDGDVYFAVMKH
HGYGKLSGRDLNEQQQNADGRVADAEEARKQHSFDFALWKGAKTGEPSFPSPWGAGRPGWHIECSAMVREELGETIDIHL
GGADLIFPHHENEIAQSEAATGKQLARYWLHNGMVNVGGQKMSKSLGNFTTIRALLESGVSPMTLRLFILQAHYRKPLDF
TADAINAAATGWKGLNAALGLGNIYAEALNWPECKPLPQEVMQPAHSSTLEQCSEIRQHFIDALDDDLNSSGAIAVLFDL
ARPLRALANRLERGDTKAIQETAQLNLLPRWQLLVELANVLGLEAEKAAKLAPEGNNRVDENHIQLAIAARKEAKAARDF
AKADRIRDELRAQGIELIDKPGGLTDWISS

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=319, Percent_Identity=43.5736677115987, Blast_Score=235, Evalue=9e-62,
Organism=Homo sapiens, GI10835051, Length=239, Percent_Identity=42.6778242677824, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI303304987, Length=239, Percent_Identity=42.6778242677824, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI21269877, Length=239, Percent_Identity=42.6778242677824, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI62240992, Length=239, Percent_Identity=42.6778242677824, Blast_Score=187, Evalue=2e-47,
Organism=Escherichia coli, GI1786737, Length=495, Percent_Identity=43.2323232323232, Blast_Score=350, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI17509795, Length=318, Percent_Identity=34.2767295597484, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17509797, Length=309, Percent_Identity=34.3042071197411, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324082, Length=242, Percent_Identity=40.495867768595, Blast_Score=177, Evalue=4e-45,
Organism=Drosophila melanogaster, GI19922218, Length=399, Percent_Identity=34.3358395989975, Blast_Score=198, Evalue=6e-51,
Organism=Drosophila melanogaster, GI19922364, Length=242, Percent_Identity=42.9752066115703, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56573; Mature: 56442

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALASKQAPALPVSLRLTNTLTRRTEPFTPLKDGHVSIYCCGVTVYDLCHLGHARSYIAW
CCCCCCCCCCCEEEEEEHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHCCHHHHHHH
DVLRRYLLWRGYSVTFVQNFTDIDDKILKRAAEKKCSMEHISEQNIEAFHQDMDALGILR
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PDRMPRATQCLDGIRALIGELETSGAAYSVDGDVYFAVMKHHGYGKLSGRDLNEQQQNAD
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCCCCHHHHCCC
GRVADAEEARKQHSFDFALWKGAKTGEPSFPSPWGAGRPGWHIECSAMVREELGETIDIH
CCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEE
LGGADLIFPHHENEIAQSEAATGKQLARYWLHNGMVNVGGQKMSKSLGNFTTIRALLESG
ECCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHCHHHHHHHHHHCC
VSPMTLRLFILQAHYRKPLDFTADAINAAATGWKGLNAALGLGNIYAEALNWPECKPLPQ
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCH
EVMQPAHSSTLEQCSEIRQHFIDALDDDLNSSGAIAVLFDLARPLRALANRLERGDTKAI
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
QETAQLNLLPRWQLLVELANVLGLEAEKAAKLAPEGNNRVDENHIQLAIAARKEAKAARD
HHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHH
FAKADRIRDELRAQGIELIDKPGGLTDWISS
HHHHHHHHHHHHHCCCCEECCCCCCHHHHCC
>Mature Secondary Structure 
ALASKQAPALPVSLRLTNTLTRRTEPFTPLKDGHVSIYCCGVTVYDLCHLGHARSYIAW
CCCCCCCCCCEEEEEEHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHCCHHHHHHH
DVLRRYLLWRGYSVTFVQNFTDIDDKILKRAAEKKCSMEHISEQNIEAFHQDMDALGILR
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PDRMPRATQCLDGIRALIGELETSGAAYSVDGDVYFAVMKHHGYGKLSGRDLNEQQQNAD
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCCCCHHHHCCC
GRVADAEEARKQHSFDFALWKGAKTGEPSFPSPWGAGRPGWHIECSAMVREELGETIDIH
CCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEE
LGGADLIFPHHENEIAQSEAATGKQLARYWLHNGMVNVGGQKMSKSLGNFTTIRALLESG
ECCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHCHHHHHHHHHHCC
VSPMTLRLFILQAHYRKPLDFTADAINAAATGWKGLNAALGLGNIYAEALNWPECKPLPQ
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCH
EVMQPAHSSTLEQCSEIRQHFIDALDDDLNSSGAIAVLFDLARPLRALANRLERGDTKAI
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
QETAQLNLLPRWQLLVELANVLGLEAEKAAKLAPEGNNRVDENHIQLAIAARKEAKAARD
HHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHH
FAKADRIRDELRAQGIELIDKPGGLTDWISS
HHHHHHHHHHHHHCCCCEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA