Click here to switch to the map view.

The map label for this gene is trpF [H]

Identifier: 124022495

GI number: 124022495

Start: 720867

End: 721544

Strand: Reverse

Name: trpF [H]

Synonym: P9303_07861

Alternate gene names: 124022495

Gene position: 721544-720867 (Counterclockwise)

Preceding gene: 124022497

Following gene: 124022486

Centisome position: 26.9

GC content: 56.19

Gene sequence:

>678_bases
ATGGTCTTGCCTATGGGGTCTCCCACATCCACCGCAGTGAAGATCTGCGGTCTTACCAACATTGACCAAGCCAAATCGAT
TGCAGCACTGGGTGTCGAAGCAATTGGCGTGATCGGCGTTGCAAGCTCACCCCGCTATCTCGCAGAACAGCAACGACGAG
ACCTTTTCGCTCAACTGAACAGCTTCAAGCCAGAACTCCAACGGGTCTGGGTGGTCGCTGATCCAAATGACCTCGACCTA
GCCGAAGCCCTGCAAGGAGAAGGTGCACCGTCGGCAATCCAGCTTCACGGCCAAGAAACTCCAGAACACTGCGCAAACCT
GCGCAGGCAACACCCGAACACGCAGTGGTGGAAAGCCCTGCGCATACGTAGCCATGAGGATCTATCCCTTGCCCATACCT
ATGCAGGCCAGGTCGACGCGCTACTCCTCGATGCATGGAGGCCTGGACAACTAGGTGGCACAGGGCATCGCCTTCCCCTG
AACTGGCTGCATCAAGCCTCTTTTGAACTGCCCTGGTGGTTGGCGGGTGGTGTCTGCGCAGAGTGGATTCCAGAACTTTT
GAGCCAGGTGAATCCATGGGGCTTGGATGCCTCAAGCCGTCTCGAGATTTCGCCAGGGATCAAGGATCTAAAACTGGTTG
AGGCCCTGGTTCAAGCGGTACGTCAGCAGCAAAAATAG

Upstream 100 bases:

>100_bases
CCCGAATCTTCATCAGCTCCCAGCCTTCGCCCACCCTTTCATCTCCATCGAGCCGGATCAGCGGCCAGTAGCAAACCAAT
CTTAGAAAAGTCTCGAGCCA

Downstream 100 bases:

>100_bases
ATTCAGTGATGTAATCAAGGCTCTTAAACAATTTGAGCTGCAGCAGATTTTTTCAATGGGTTGAAATTGAATTTCGGCGA
TAAAGGGCGAGTAGGCAATA

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MVLPMGSPTSTAVKICGLTNIDQAKSIAALGVEAIGVIGVASSPRYLAEQQRRDLFAQLNSFKPELQRVWVVADPNDLDL
AEALQGEGAPSAIQLHGQETPEHCANLRRQHPNTQWWKALRIRSHEDLSLAHTYAGQVDALLLDAWRPGQLGGTGHRLPL
NWLHQASFELPWWLAGGVCAEWIPELLSQVNPWGLDASSRLEISPGIKDLKLVEALVQAVRQQQK

Sequences:

>Translated_225_residues
MVLPMGSPTSTAVKICGLTNIDQAKSIAALGVEAIGVIGVASSPRYLAEQQRRDLFAQLNSFKPELQRVWVVADPNDLDL
AEALQGEGAPSAIQLHGQETPEHCANLRRQHPNTQWWKALRIRSHEDLSLAHTYAGQVDALLLDAWRPGQLGGTGHRLPL
NWLHQASFELPWWLAGGVCAEWIPELLSQVNPWGLDASSRLEISPGIKDLKLVEALVQAVRQQQK
>Mature_225_residues
MVLPMGSPTSTAVKICGLTNIDQAKSIAALGVEAIGVIGVASSPRYLAEQQRRDLFAQLNSFKPELQRVWVVADPNDLDL
AEALQGEGAPSAIQLHGQETPEHCANLRRQHPNTQWWKALRIRSHEDLSLAHTYAGQVDALLLDAWRPGQLGGTGHRLPL
NWLHQASFELPWWLAGGVCAEWIPELLSQVNPWGLDASSRLEISPGIKDLKLVEALVQAVRQQQK

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=209, Percent_Identity=32.5358851674641, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 24760; Mature: 24760

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLPMGSPTSTAVKICGLTNIDQAKSIAALGVEAIGVIGVASSPRYLAEQQRRDLFAQLN
CCCCCCCCCHHHEEEECCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHH
SFKPELQRVWVVADPNDLDLAEALQGEGAPSAIQLHGQETPEHCANLRRQHPNTQWWKAL
CCCCCCEEEEEEECCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHH
RIRSHEDLSLAHTYAGQVDALLLDAWRPGQLGGTGHRLPLNWLHQASFELPWWLAGGVCA
HHCCCCCCHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHCCHHH
EWIPELLSQVNPWGLDASSRLEISPGIKDLKLVEALVQAVRQQQK
HHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVLPMGSPTSTAVKICGLTNIDQAKSIAALGVEAIGVIGVASSPRYLAEQQRRDLFAQLN
CCCCCCCCCHHHEEEECCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHH
SFKPELQRVWVVADPNDLDLAEALQGEGAPSAIQLHGQETPEHCANLRRQHPNTQWWKAL
CCCCCCEEEEEEECCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHH
RIRSHEDLSLAHTYAGQVDALLLDAWRPGQLGGTGHRLPLNWLHQASFELPWWLAGGVCA
HHCCCCCCHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHCCHHH
EWIPELLSQVNPWGLDASSRLEISPGIKDLKLVEALVQAVRQQQK
HHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA