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The map label for this gene is infC

Identifier: 124021868

GI number: 124021868

Start: 172786

End: 173445

Strand: Reverse

Name: infC

Synonym: P9303_01551

Alternate gene names: 124021868

Gene position: 173445-172786 (Counterclockwise)

Preceding gene: 124021869

Following gene: 124021866

Centisome position: 6.47

GC content: 51.67

Gene sequence:

>660_bases
ATGCCACCACGTCCTCGTTTTGACCGTCGCGCACCCGTCAGGGAGCTCCCCAACATTAATGACCGCATCAATTATCCCAA
GTTGCGGGTCGTTGACGCAGACGGAACTCAGCTCGGGGTGATCAACAGGGAAGAAGCCCTTGATGTAGCAAAAGATAGGG
AACTCGATCTGGTCCTTGTCAGCGAGAAAGCGGATCCACCCGTTTGCCGAATCATGGATTACGGCAAATTCAAGTTTGAG
CAGGAGAAGAAAGCCAAGGAAGCCAAAAAGAAGTCGCATCAGACCGAAGTCAAAGAAGTCAAAATGCGCTACAAAATCGA
TCAGCACGACTACAACGTGCGCATCGGCCAAGCCGTGCGATTCCTCAAGGCTGGTGACAAAGTCAAGTGCACCGTTATCT
TCCGGGGTCGGGAAATTCAGCACACTGCCCTGGCTGAAACGCTGCTACGACGTATGGCAAAAGACCTGGAAGAGCAGGCC
GAAATTCAGCAAGCTCCTAAGCGTGAAGGTCGGAACATGATCATGTTCCTTACACCGCGCAAAACACCGCTGATCAAAAC
AGATAAGGAAAACCAAATTCCTACCCGTGCGGTTCGCACCATCACAGCCCCACCTCGAGCCACTACTGCTGCCAAAACAC
AGCTCAACAAGGATCAATAA

Upstream 100 bases:

>100_bases
GCGAAGCGCTATCACTGATTCAAGCGGGTCTAAGGTGAAGGGTGCAGACATAAAACCTTCTGGTCTCCTTGTCGTCTGCT
CTATTCCCTTATCTCACTGA

Downstream 100 bases:

>100_bases
ATTCCTAACTTCAGAGAAATCAAGCACCTGCTAGCCCTTGAGAGCAACCTGAACCACTAAGTGTGTTCTGGTCGATCAAT
TAAGAGGGGTCGACCCCTCT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MPPRPRFDRRAPVRELPNINDRINYPKLRVVDADGTQLGVINREEALDVAKDRELDLVLVSEKADPPVCRIMDYGKFKFE
QEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYNVRIGQAVRFLKAGDKVKCTVIFRGREIQHTALAETLLRRMAKDLEEQA
EIQQAPKREGRNMIMFLTPRKTPLIKTDKENQIPTRAVRTITAPPRATTAAKTQLNKDQ

Sequences:

>Translated_219_residues
MPPRPRFDRRAPVRELPNINDRINYPKLRVVDADGTQLGVINREEALDVAKDRELDLVLVSEKADPPVCRIMDYGKFKFE
QEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYNVRIGQAVRFLKAGDKVKCTVIFRGREIQHTALAETLLRRMAKDLEEQA
EIQQAPKREGRNMIMFLTPRKTPLIKTDKENQIPTRAVRTITAPPRATTAAKTQLNKDQ
>Mature_218_residues
PPRPRFDRRAPVRELPNINDRINYPKLRVVDADGTQLGVINREEALDVAKDRELDLVLVSEKADPPVCRIMDYGKFKFEQ
EKKAKEAKKKSHQTEVKEVKMRYKIDQHDYNVRIGQAVRFLKAGDKVKCTVIFRGREIQHTALAETLLRRMAKDLEEQAE
IQQAPKREGRNMIMFLTPRKTPLIKTDKENQIPTRAVRTITAPPRATTAAKTQLNKDQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=46.7065868263473, Blast_Score=134, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_PROM3 (A2C600)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016175.1
- ProteinModelPortal:   A2C600
- STRING:   A2C600
- GeneID:   4776667
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_01551
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   FDRRAPV
- ProtClustDB:   PRK00028
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 25354; Mature: 25223

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRPRFDRRAPVRELPNINDRINYPKLRVVDADGTQLGVINREEALDVAKDRELDLVLV
CCCCCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCEEEEECHHHHHHHHCCCCEEEEEE
SEKADPPVCRIMDYGKFKFEQEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYNVRIGQAVR
ECCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHH
FLKAGDKVKCTVIFRGREIQHTALAETLLRRMAKDLEEQAEIQQAPKREGRNMIMFLTPR
HHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKTDKENQIPTRAVRTITAPPRATTAAKTQLNKDQ
CCCCEECCCCCCCCHHHHEEECCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
PPRPRFDRRAPVRELPNINDRINYPKLRVVDADGTQLGVINREEALDVAKDRELDLVLV
CCCCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCEEEEECHHHHHHHHCCCCEEEEEE
SEKADPPVCRIMDYGKFKFEQEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYNVRIGQAVR
ECCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHH
FLKAGDKVKCTVIFRGREIQHTALAETLLRRMAKDLEEQAEIQQAPKREGRNMIMFLTPR
HHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKTDKENQIPTRAVRTITAPPRATTAAKTQLNKDQ
CCCCEECCCCCCCCHHHHEEECCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA