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The map label for this gene is aroB [H]

Identifier: 124021856

GI number: 124021856

Start: 157075

End: 158193

Strand: Direct

Name: aroB [H]

Synonym: P9303_01431

Alternate gene names: 124021856

Gene position: 157075-158193 (Clockwise)

Preceding gene: 124021855

Following gene: 124021857

Centisome position: 5.86

GC content: 45.93

Gene sequence:

>1119_bases
ATGGCTGATCCGTTGACCCTCGATATCCAAAGCTCTTATGCCAATTACAAGGTTGCTTTTTCGGATCTCAATGATTTGAG
CAAATGTTGCTTTGAAGCTGACGCCTTTTTGGTGGATGCATTTTTTCGTGATCGCCTGCCATTGCCTGCAAATGTCCCTG
TGGTCTGGATTGAGTCGAATGAGGATGCCAAGGCACTGCCAGCCACCATTGACGTGTTTGTCGCTCTCAAACAAGCAGGA
CTCGGCCGTGGCTCACATCTCATCGCGATCGGCGGCGGAGTCATTCAAGACATTGCAACCTTTGTGGCGTCTTTATATAT
GCGCGGAATTAGTTGGAGTTACGTCCCAACTACATTTTTGGGCATGGTTGATTCCTGCCTAGGTGGCAAGAGTTCTATTA
ATGTTGGTCCTTATAAGAATCTTGTCGGTAACTTTCATCCGCCGCGCCGTATTGATATTTTGCCTGTTTTTGCCCGCTCT
TTACCGATGGTCGAGATGGCAGGTGGAGCGGCAGAGGCCGCAAAGATTTCTTTTTGTAGAGGCAAGACAGCTTTTGCGAA
TTATGAGCAGTTAGCATCTCCAGTGCTTGCTGGAGCTTGGACAGAAGAAGAACTCGCTCAATTACTTCATGCAACTTTGG
CCGTTAAGAAGTGGTTTATCGAAAAAGATGAATTTGATCAGGCTGAGAGGCGGCTACTTAATTTTGGCCATACATGGGGC
CATGCCCTTGAATCTGCAACAGCCTTTGCTATTCCCCATGGCTTGGCAGTGGGTCTTGGCATGATGGCATCCATACGATT
TGTTGGTACAGAGATAACCGACTCTTTACTCTGGCAACATTGCATGAATCTGTTGAAGCCTATCTTGTTACTTAAGCAAT
TGACTGTCTTTGATGCCGATGTTTTTGTCAAAGCTTTTCGGGCTGACAAGAAACATTCTTCAGGCCATTTTCACTTGATT
GTTCCTGCGGCTGTGGCTGATTCTGGATTGGGTGTTGAGGAGATTCGCTTGAGATCTGATGATGCTTCCTTGGCTCGTAT
TTTGAAGGCGATGCAAGAGGTTTTGGCTATTGTTTCTGATGAACTATCAGATAAAAAGTCTTTAGCCAATCGATTATGA

Upstream 100 bases:

>100_bases
CCGTAGCGTTCTTGGCGGACTCCTCCAACCGGGTGATCACAGGTCAGTTCCTTACAGTTGATGCTGGGTTCATTGGTATG
AAGCATTCCTGAGAACCGTT

Downstream 100 bases:

>100_bases
TGAAGTATTCAGATGTTGTTTTTCAATGGCTTAAACGGAGTGGCTATAGCCATTGTTACTTTGTGGCGGGTGGCAATATT
ATGCACCTCCTAAATTCAGC

Product: 3-dehydroquinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MADPLTLDIQSSYANYKVAFSDLNDLSKCCFEADAFLVDAFFRDRLPLPANVPVVWIESNEDAKALPATIDVFVALKQAG
LGRGSHLIAIGGGVIQDIATFVASLYMRGISWSYVPTTFLGMVDSCLGGKSSINVGPYKNLVGNFHPPRRIDILPVFARS
LPMVEMAGGAAEAAKISFCRGKTAFANYEQLASPVLAGAWTEEELAQLLHATLAVKKWFIEKDEFDQAERRLLNFGHTWG
HALESATAFAIPHGLAVGLGMMASIRFVGTEITDSLLWQHCMNLLKPILLLKQLTVFDADVFVKAFRADKKHSSGHFHLI
VPAAVADSGLGVEEIRLRSDDASLARILKAMQEVLAIVSDELSDKKSLANRL

Sequences:

>Translated_372_residues
MADPLTLDIQSSYANYKVAFSDLNDLSKCCFEADAFLVDAFFRDRLPLPANVPVVWIESNEDAKALPATIDVFVALKQAG
LGRGSHLIAIGGGVIQDIATFVASLYMRGISWSYVPTTFLGMVDSCLGGKSSINVGPYKNLVGNFHPPRRIDILPVFARS
LPMVEMAGGAAEAAKISFCRGKTAFANYEQLASPVLAGAWTEEELAQLLHATLAVKKWFIEKDEFDQAERRLLNFGHTWG
HALESATAFAIPHGLAVGLGMMASIRFVGTEITDSLLWQHCMNLLKPILLLKQLTVFDADVFVKAFRADKKHSSGHFHLI
VPAAVADSGLGVEEIRLRSDDASLARILKAMQEVLAIVSDELSDKKSLANRL
>Mature_371_residues
ADPLTLDIQSSYANYKVAFSDLNDLSKCCFEADAFLVDAFFRDRLPLPANVPVVWIESNEDAKALPATIDVFVALKQAGL
GRGSHLIAIGGGVIQDIATFVASLYMRGISWSYVPTTFLGMVDSCLGGKSSINVGPYKNLVGNFHPPRRIDILPVFARSL
PMVEMAGGAAEAAKISFCRGKTAFANYEQLASPVLAGAWTEEELAQLLHATLAVKKWFIEKDEFDQAERRLLNFGHTWGH
ALESATAFAIPHGLAVGLGMMASIRFVGTEITDSLLWQHCMNLLKPILLLKQLTVFDADVFVKAFRADKKHSSGHFHLIV
PAAVADSGLGVEEIRLRSDDASLARILKAMQEVLAIVSDELSDKKSLANRL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=298, Percent_Identity=32.5503355704698, Blast_Score=113, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320332, Length=376, Percent_Identity=27.1276595744681, Blast_Score=103, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40534; Mature: 40403

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPLTLDIQSSYANYKVAFSDLNDLSKCCFEADAFLVDAFFRDRLPLPANVPVVWIESN
CCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
EDAKALPATIDVFVALKQAGLGRGSHLIAIGGGVIQDIATFVASLYMRGISWSYVPTTFL
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
GMVDSCLGGKSSINVGPYKNLVGNFHPPRRIDILPVFARSLPMVEMAGGAAEAAKISFCR
HHHHHHCCCCCCCCCCCHHHHHCCCCCCCEEEHHHHHHHCCCCHHCCCCCHHHHHHHHHC
GKTAFANYEQLASPVLAGAWTEEELAQLLHATLAVKKWFIEKDEFDQAERRLLNFGHTWG
CCCHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
HALESATAFAIPHGLAVGLGMMASIRFVGTEITDSLLWQHCMNLLKPILLLKQLTVFDAD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFVKAFRADKKHSSGHFHLIVPAAVADSGLGVEEIRLRSDDASLARILKAMQEVLAIVSD
HHHHHHHCCCCCCCCCEEEEEEHHHCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHHHH
ELSDKKSLANRL
HHHHHHHHHHCC
>Mature Secondary Structure 
ADPLTLDIQSSYANYKVAFSDLNDLSKCCFEADAFLVDAFFRDRLPLPANVPVVWIESN
CCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
EDAKALPATIDVFVALKQAGLGRGSHLIAIGGGVIQDIATFVASLYMRGISWSYVPTTFL
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
GMVDSCLGGKSSINVGPYKNLVGNFHPPRRIDILPVFARSLPMVEMAGGAAEAAKISFCR
HHHHHHCCCCCCCCCCCHHHHHCCCCCCCEEEHHHHHHHCCCCHHCCCCCHHHHHHHHHC
GKTAFANYEQLASPVLAGAWTEEELAQLLHATLAVKKWFIEKDEFDQAERRLLNFGHTWG
CCCHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
HALESATAFAIPHGLAVGLGMMASIRFVGTEITDSLLWQHCMNLLKPILLLKQLTVFDAD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFVKAFRADKKHSSGHFHLIVPAAVADSGLGVEEIRLRSDDASLARILKAMQEVLAIVSD
HHHHHHHCCCCCCCCCEEEEEEHHHCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHHHH
ELSDKKSLANRL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA