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The map label for this gene is spsE

Identifier: 124021823

GI number: 124021823

Start: 110482

End: 111489

Strand: Reverse

Name: spsE

Synonym: P9303_01101

Alternate gene names: NA

Gene position: 111489-110482 (Counterclockwise)

Preceding gene: 124021824

Following gene: 124021822

Centisome position: 4.16

GC content: 37.6

Gene sequence:

>1008_bases
ATGGCCGTTAAGATAATAGCAGAGGCAGGTGTCAACCATAATGGCGAAATACAAAATGCATATCGACTAATAGATAGTGC
GAAGTTTGCTGGTGCTGACGCAATAAAGTTCCAAAGCTTTTCGTCAATAGAATTGACCGCAGAGAATGCACCAAAAGCAA
AGTATCAGCAAATGTACGCTGACAGAAGCACTCAACGTGAAATGTTGGCACGGCTTGAACTTAATGAAATGGAGCATCAG
CTGATAGCAGACTATTGTGAGAAAATTGAGATAGAGTTTCTATCAACAGCGTTTGGGCAATCGCAACTAGACTTATTAAT
TAAACTAAAGGTTCAGGCGATTAAAGTGGCCTCAGGAGAAATAACACACTGGCCATTATTAAAGGAAATGGCAAAAAAAG
CCTATGAAAATAATCTAGATGTCTATCTATCTACAGGAATGTCAGAAATAAAAGAAATCCAGGATGCACTAGATATTTTT
ATCAAGGAAGATATTTCATTAGGGAAAATTTTTATCCTACATTGTACTAGTCATTATCCTGCTCCTTACAACGCTGTCAA
TATGAAAGCACTAAGGACATTGAGAAATACATTTCAATGTAAAGTTGGATACTCAGACCATACCACAGGGATACTTACAT
CAGTTGTTGCTGTAGCGCTTGGTGCTGAAATTATTGAAAAGCACATAACACTTGATCAAGCAATGAAAGGTCCAGATCAT
AAAGCCAGTTTAAATCCACAAGAGTTTAGAAGTATGGTAAAGGAAATTAGAAATTGTGAGGAGATACTTGGACAAGAAGA
GAAAACACTGCAAGATTGCGAACGAGATACTAGGTATGTAGCCAGACGCTCTATCAGAGCATCTGAAATCATAAATAAAG
GTGATGTCTTAAATGAGAAGAATCTGATATGCAAGCGCCCTAATGATGGGATAAGTCCTATGAATTATCCGCAAATATTA
GGTAAACGTGCAAAGCGCGAATACGAAATTGGTGAATGTATTGACTAG

Upstream 100 bases:

>100_bases
AAATAGGGAGTGATTGCTTTATAGGAAGCGGATGTATCATCCGTGAAGGCCTAAAAGTTCCTGATGGTACTATAATAAGT
GCAGGTACAAGAGTAATGGG

Downstream 100 bases:

>100_bases
TAATAAAACAAAGATCGGAATATTTACTGGCACAAGGGCAGAATATGGACTAATGAGAACCCTGATCAGGAAATTAGTTG
ATCATCCTGATTATGATACG

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAVKIIAEAGVNHNGEIQNAYRLIDSAKFAGADAIKFQSFSSIELTAENAPKAKYQQMYADRSTQREMLARLELNEMEHQ
LIADYCEKIEIEFLSTAFGQSQLDLLIKLKVQAIKVASGEITHWPLLKEMAKKAYENNLDVYLSTGMSEIKEIQDALDIF
IKEDISLGKIFILHCTSHYPAPYNAVNMKALRTLRNTFQCKVGYSDHTTGILTSVVAVALGAEIIEKHITLDQAMKGPDH
KASLNPQEFRSMVKEIRNCEEILGQEEKTLQDCERDTRYVARRSIRASEIINKGDVLNEKNLICKRPNDGISPMNYPQIL
GKRAKREYEIGECID

Sequences:

>Translated_335_residues
MAVKIIAEAGVNHNGEIQNAYRLIDSAKFAGADAIKFQSFSSIELTAENAPKAKYQQMYADRSTQREMLARLELNEMEHQ
LIADYCEKIEIEFLSTAFGQSQLDLLIKLKVQAIKVASGEITHWPLLKEMAKKAYENNLDVYLSTGMSEIKEIQDALDIF
IKEDISLGKIFILHCTSHYPAPYNAVNMKALRTLRNTFQCKVGYSDHTTGILTSVVAVALGAEIIEKHITLDQAMKGPDH
KASLNPQEFRSMVKEIRNCEEILGQEEKTLQDCERDTRYVARRSIRASEIINKGDVLNEKNLICKRPNDGISPMNYPQIL
GKRAKREYEIGECID
>Mature_334_residues
AVKIIAEAGVNHNGEIQNAYRLIDSAKFAGADAIKFQSFSSIELTAENAPKAKYQQMYADRSTQREMLARLELNEMEHQL
IADYCEKIEIEFLSTAFGQSQLDLLIKLKVQAIKVASGEITHWPLLKEMAKKAYENNLDVYLSTGMSEIKEIQDALDIFI
KEDISLGKIFILHCTSHYPAPYNAVNMKALRTLRNTFQCKVGYSDHTTGILTSVVAVALGAEIIEKHITLDQAMKGPDHK
ASLNPQEFRSMVKEIRNCEEILGQEEKTLQDCERDTRYVARRSIRASEIINKGDVLNEKNLICKRPNDGISPMNYPQILG
KRAKREYEIGECID

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=323, Percent_Identity=33.1269349845201, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI21357081, Length=350, Percent_Identity=31.4285714285714, Blast_Score=150, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 37892; Mature: 37761

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKIIAEAGVNHNGEIQNAYRLIDSAKFAGADAIKFQSFSSIELTAENAPKAKYQQMYA
CCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHEECCCCCEEEECCCCCHHHHHHHHH
DRSTQREMLARLELNEMEHQLIADYCEKIEIEFLSTAFGQSQLDLLIKLKVQAIKVASGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEHHHHEEECCCC
ITHWPLLKEMAKKAYENNLDVYLSTGMSEIKEIQDALDIFIKEDISLGKIFILHCTSHYP
CCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
APYNAVNMKALRTLRNTFQCKVGYSDHTTGILTSVVAVALGAEIIEKHITLDQAMKGPDH
CCCCHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KASLNPQEFRSMVKEIRNCEEILGQEEKTLQDCERDTRYVARRSIRASEIINKGDVLNEK
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NLICKRPNDGISPMNYPQILGKRAKREYEIGECID
CCEEECCCCCCCCCCHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure 
AVKIIAEAGVNHNGEIQNAYRLIDSAKFAGADAIKFQSFSSIELTAENAPKAKYQQMYA
CEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHEECCCCCEEEECCCCCHHHHHHHHH
DRSTQREMLARLELNEMEHQLIADYCEKIEIEFLSTAFGQSQLDLLIKLKVQAIKVASGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEHHHHEEECCCC
ITHWPLLKEMAKKAYENNLDVYLSTGMSEIKEIQDALDIFIKEDISLGKIFILHCTSHYP
CCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
APYNAVNMKALRTLRNTFQCKVGYSDHTTGILTSVVAVALGAEIIEKHITLDQAMKGPDH
CCCCHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KASLNPQEFRSMVKEIRNCEEILGQEEKTLQDCERDTRYVARRSIRASEIINKGDVLNEK
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NLICKRPNDGISPMNYPQILGKRAKREYEIGECID
CCEEECCCCCCCCCCHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]