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The map label for this gene is rfbC [H]

Identifier: 124021807

GI number: 124021807

Start: 94031

End: 94636

Strand: Direct

Name: rfbC [H]

Synonym: P9303_00941

Alternate gene names: 124021807

Gene position: 94031-94636 (Clockwise)

Preceding gene: 124021805

Following gene: 124021808

Centisome position: 3.51

GC content: 51.65

Gene sequence:

>606_bases
ATGCAAGCTGAAGTCCTGACCTCCGCGGCAGGGATCCATCTAAACGGACCTTTGTTGTTGTCTCCTCAGGTGCATGGCGA
TGAAAGAGGATTTTTCTTTGAGAGTTGGAATCAGCGTCGTTGGCAGGAGGTTTTGGCAAGTCATAGGCAGGAAGCGCCTG
AGTTTGTCCAAGACAATCACTCGCGTTCGTCTTGTGGCGTGCTGCGTGGACTGCACTATCAATTGCCCCCGCATCCCCAG
GGCAAGCTGGTGCGTTGCGTAGTAGGTGAGATCTTTGATGTTGCTATTGATCTGCGCCGTTCTTCAGCAACCTATGGTCA
GTGGGCCGGAGCTCATTTGAGTGCTGAGAACCATCAGCAGCTTTGGATACCGGTTGGCTTTGCCCATGGTTTTCTGACTC
TCTCAGAGAGTGCTGAGGTGCTTTATAAAGCCACGGATTTCTGGAGTCGCGATTGTGAACGGGCGATCCGCTGGGATGAT
CCACGCCTAGGAATTTCCTGGCCTGTTGTTCACGTGGATGGAGATCAGATTCCAGCATCTCTTTCTCAGAAGGATGCTGT
TGCTTCTTTGATGGAGGAGTTGTCTGCAGCTGAAACCTTCAAATGA

Upstream 100 bases:

>100_bases
ACGGCCGAGCAGTTGGCCAATTTGGCTGCTCCCCTATGCAAGAGCGGTTATGGCGACTACCTCCTGCAGATTCTTGAGAA
TCCTCACTCTGGATCCATCA

Downstream 100 bases:

>100_bases
AGGGCATATAAGCCCCTTAGTATTAGCTGAGAGACGGCTGAAACCTTCAAATGAAGGGCATACAAACACCTTTTTTTGAC
TAGCCTGAATGCAATGCTTG

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MQAEVLTSAAGIHLNGPLLLSPQVHGDERGFFFESWNQRRWQEVLASHRQEAPEFVQDNHSRSSCGVLRGLHYQLPPHPQ
GKLVRCVVGEIFDVAIDLRRSSATYGQWAGAHLSAENHQQLWIPVGFAHGFLTLSESAEVLYKATDFWSRDCERAIRWDD
PRLGISWPVVHVDGDQIPASLSQKDAVASLMEELSAAETFK

Sequences:

>Translated_201_residues
MQAEVLTSAAGIHLNGPLLLSPQVHGDERGFFFESWNQRRWQEVLASHRQEAPEFVQDNHSRSSCGVLRGLHYQLPPHPQ
GKLVRCVVGEIFDVAIDLRRSSATYGQWAGAHLSAENHQQLWIPVGFAHGFLTLSESAEVLYKATDFWSRDCERAIRWDD
PRLGISWPVVHVDGDQIPASLSQKDAVASLMEELSAAETFK
>Mature_201_residues
MQAEVLTSAAGIHLNGPLLLSPQVHGDERGFFFESWNQRRWQEVLASHRQEAPEFVQDNHSRSSCGVLRGLHYQLPPHPQ
GKLVRCVVGEIFDVAIDLRRSSATYGQWAGAHLSAENHQQLWIPVGFAHGFLTLSESAEVLYKATDFWSRDCERAIRWDD
PRLGISWPVVHVDGDQIPASLSQKDAVASLMEELSAAETFK

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=151, Percent_Identity=52.9801324503311, Blast_Score=170, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17550412, Length=170, Percent_Identity=44.1176470588235, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 22553; Mature: 22553

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAEVLTSAAGIHLNGPLLLSPQVHGDERGFFFESWNQRRWQEVLASHRQEAPEFVQDNH
CCCCHHHHCCCEEECCCEEECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCHHHHHCCC
SRSSCGVLRGLHYQLPPHPQGKLVRCVVGEIFDVAIDLRRSSATYGQWAGAHLSAENHQQ
CCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
LWIPVGFAHGFLTLSESAEVLYKATDFWSRDCERAIRWDDPRLGISWPVVHVDGDQIPAS
EEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCC
LSQKDAVASLMEELSAAETFK
CCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQAEVLTSAAGIHLNGPLLLSPQVHGDERGFFFESWNQRRWQEVLASHRQEAPEFVQDNH
CCCCHHHHCCCEEECCCEEECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCHHHHHCCC
SRSSCGVLRGLHYQLPPHPQGKLVRCVVGEIFDVAIDLRRSSATYGQWAGAHLSAENHQQ
CCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
LWIPVGFAHGFLTLSESAEVLYKATDFWSRDCERAIRWDDPRLGISWPVVHVDGDQIPAS
EEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCC
LSQKDAVASLMEELSAAETFK
CCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609; 10802738 [H]