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The map label for this gene is clpX

Identifier: 124021783

GI number: 124021783

Start: 66333

End: 67691

Strand: Reverse

Name: clpX

Synonym: P9303_00681

Alternate gene names: 124021783

Gene position: 67691-66333 (Counterclockwise)

Preceding gene: 124021784

Following gene: 124021782

Centisome position: 2.52

GC content: 54.23

Gene sequence:

>1359_bases
ATGGCCAAATTCGACGCCCATCTAAAGTGCTCTTTCTGCGGCAAGTCTCAGGACCAAGTACGCAAATTGATTGCCGGGCC
AGGTGTCTACATCTGCGACGAATGCATCGATCTCTGCACCGAGATCCTGGATGAAGAGCTTGTCGATAGCCAAGGCAACC
CACGTCACAGCAGCGAGTCCAATCGCAAGTCTGCAACTGCTTCCCATAAAAGTGGAAAGCCAGCACCCACACTCGCCACC
ATACCCAAACCTCAGGAGATCAAAAACTTCCTAGATAAGCAAGTAGTGGGGCAAGAAGCTGCCAAAAAAGTACTTTCAGT
CGCCGTCTATAACCACTACAAACGCCTGGCTTGGCAAGGTGACGGCCAAGGTGAAACCGATCTCTCTGCAACCAGGCTCC
ACAAGTCAAACATCCTGCTCATCGGTCCAACAGGCTGTGGCAAAACCCTATTAGCCCAGACCCTGGCCGAACTCCTGGAC
GTGCCCTTCGCCGTTGCTGATGCAACCACACTGACCGAAGCCGGCTACGTGGGCGAGGATGTCGAAAACATTTTGCTGCG
GCTATTGCAAAAAGCCGACATGGACGTGGAGCATGCCCAGCGCGGCATCATTTACGTCGATGAGATCGATAAGATCGCCC
GAAAAAGTGAAAACCCCTCCATCACCCGCGACGTATCCGGTGAAGGAGTACAGCAAGCCCTGCTAAAGATGCTCGAAGGC
ACAGTCGCCAACGTGCCCCCCCAAGGAGGGCGTAAACACCCCTATCAAGACTGCATCCAAATCGACACCAGCCAGATCCT
CTTCATCTGCGGTGGTGCCTTCATTGGCCTCGAAGATGTGGTGCAACGGCGACTAGGCCGTAATGCCATCGGTTTTATGC
CCAGCGATGGTCGAGGGCGCAGCCGTGCCAATCGTGATCTAAAGGCCTCACAGGTGCTTCACCACCTTGAAGCCGACGAC
CTCGTGCGTTATGGCTTGATCCCTGAATTCATTGGCCGCATTCCCGTGAGTGCAGTGCTTGAACCACTTGATTCACAAGC
ACTCGAATCGATTCTCACGGAGCCTCGTGACGCACTGGTCAAGCAATTCAGCACCCTGCTGAGCATGGACAACGTGCAGC
TTGAGTTTGAATCAGATGCCGTAGAAGCTATCGCCCAGGAAGCACATCGGCGCAAGACCGGGGCCCGAGCACTACGAGGC
ATCATCGAAGAGTTAATGCTGGATTTGATGTACGACCTTCCCTCCAAGAAGAACGTGAAGAAATTCACCGTGACCCGCAC
GATGGTTGATGAACATACCGGCGGCAAGGTTCTGCCTCTACCAGCCAACGACGAGCGATCGCATAAGGAATCAGCCTGA

Upstream 100 bases:

>100_bases
ACGGAAGGGTGACGCAACCCTGATCTGACACGATCCTGAGCGTTCAGGCTGGCCAACATTCGTCAGATCCTGTCTGCCCG
TTTGCAGTGATCACAGCCCG

Downstream 100 bases:

>100_bases
TCCATTGGGGACGGCTGACCACCTACGGGTGCCCCGCCAGCAAGGAATTTTTTTGCATCGCGAAATTGATGTTGGAGATG
GCAGCTTCGCTCACTATCTA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSESNRKSATASHKSGKPAPTLAT
IPKPQEIKNFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQGDGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLD
VPFAVADATTLTEAGYVGEDVENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
TVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQRRLGRNAIGFMPSDGRGRSRANRDLKASQVLHHLEADD
LVRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALVKQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRG
IIEELMLDLMYDLPSKKNVKKFTVTRTMVDEHTGGKVLPLPANDERSHKESA

Sequences:

>Translated_452_residues
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSESNRKSATASHKSGKPAPTLAT
IPKPQEIKNFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQGDGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLD
VPFAVADATTLTEAGYVGEDVENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
TVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQRRLGRNAIGFMPSDGRGRSRANRDLKASQVLHHLEADD
LVRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALVKQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRG
IIEELMLDLMYDLPSKKNVKKFTVTRTMVDEHTGGKVLPLPANDERSHKESA
>Mature_451_residues
AKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSESNRKSATASHKSGKPAPTLATI
PKPQEIKNFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQGDGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLDV
PFAVADATTLTEAGYVGEDVENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGT
VANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQRRLGRNAIGFMPSDGRGRSRANRDLKASQVLHHLEADDL
VRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALVKQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRGI
IEELMLDLMYDLPSKKNVKKFTVTRTMVDEHTGGKVLPLPANDERSHKESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=303, Percent_Identity=50.4950495049505, Blast_Score=288, Evalue=5e-78,
Organism=Escherichia coli, GI1786642, Length=426, Percent_Identity=57.7464788732394, Blast_Score=477, Evalue=1e-136,
Organism=Escherichia coli, GI1790366, Length=218, Percent_Identity=30.7339449541284, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982908, Length=306, Percent_Identity=45.7516339869281, Blast_Score=268, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=293, Percent_Identity=47.7815699658703, Blast_Score=267, Evalue=8e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=412, Percent_Identity=38.1067961165049, Blast_Score=244, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=256, Percent_Identity=41.015625, Blast_Score=171, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=458, Percent_Identity=37.117903930131, Blast_Score=258, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24648289, Length=295, Percent_Identity=50.5084745762712, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24648291, Length=295, Percent_Identity=50.5084745762712, Blast_Score=285, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_PROM3 (A2C5R5)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016090.1
- ProteinModelPortal:   A2C5R5
- STRING:   A2C5R5
- GeneID:   4777999
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_00681
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 49605; Mature: 49474

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSES
CCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NRKSATASHKSGKPAPTLATIPKPQEIKNFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQG
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLDVPFAVADATTLTEAGYVGED
CCCCCCCCHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHH
VENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
HHHHHHHHHHHCCCCHHHHHCCCEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
TVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQRRLGRNAIGFMPSDGRGR
HHCCCCCCCCCCCCHHHHHHCCCHHEEEECCCHHCCHHHHHHHHHCCCCCCCCCCCCCCC
SRANRDLKASQVLHHLEADDLVRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALV
HHHCCCHHHHHHHHHCCHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHH
KQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRGIIEELMLDLMYDLPSKKNVK
HHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
KFTVTRTMVDEHTGGKVLPLPANDERSHKESA
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
AKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSES
CCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NRKSATASHKSGKPAPTLATIPKPQEIKNFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQG
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLDVPFAVADATTLTEAGYVGED
CCCCCCCCHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHH
VENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
HHHHHHHHHHHCCCCHHHHHCCCEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
TVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQRRLGRNAIGFMPSDGRGR
HHCCCCCCCCCCCCHHHHHHCCCHHEEEECCCHHCCHHHHHHHHHCCCCCCCCCCCCCCC
SRANRDLKASQVLHHLEADDLVRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALV
HHHCCCHHHHHHHHHCCHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHH
KQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRGIIEELMLDLMYDLPSKKNVK
HHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
KFTVTRTMVDEHTGGKVLPLPANDERSHKESA
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA