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The map label for this gene is pilC [H]

Identifier: 124021732

GI number: 124021732

Start: 20686

End: 21966

Strand: Reverse

Name: pilC [H]

Synonym: P9303_00171

Alternate gene names: 124021732

Gene position: 21966-20686 (Counterclockwise)

Preceding gene: 124021733

Following gene: 124021729

Centisome position: 0.82

GC content: 48.71

Gene sequence:

>1281_bases
ATGACGTCCTTCGTCGCCACCTACGAATCAGCAAGTGGTCAAACACGCACAATGACCATCAAAGCGGCCGATCTAACAAC
CGCAAAAAAGTTACTACGTCGTCGTGGAATACGAGCAACTGACCTAAAAGCAGCTCTCAACAATAAAGGACAAGAAAGTA
GCAAAAAAATTGACCGCCAAAAGAACACAAAATCTTCAAACCTTGGACTATTTTCCATCGATCTAGCTGCCGCTTTCGAA
AAGTCCCCAGGTGTAAAAGACAAAGCAGTTTTCGCAAGCAAATTGGCAACTCTGGTGGATGCAGGCGTTCCGATCGTGCG
CAGTCTCGACCTAATGGCTAATCAGCAGCGCTTGCCTATGTTCAAACGTGCACTGATGAAGGTGAGTCTTGATGTAAATG
AAGGCAGTGCCATGGGCACTGCTATGAGAATGTGGCCAAAGGTATTCGACCAACTCAGTATCGCGATGGTGGAAGCCGGA
GAGGCTGGTGGTGTTTTGGATGAATCTCTCAAGAGACTCGCCAAGCTATTAGAAGACAATGCCCGACTCAAGAACCAAAT
CAAAGGGGCTCTTGGTTACCCAATCACCGTGCTGGTGATAGCCATCCTCGTCTTCCTAGGCATGACAATCTTCTTGATCC
CGACCTTTGCAGAAATCTTTGAAGATTTAGGTGCCGAGCTGCCCCTGTTCACCCAGTTCATGGTCGACCTAAGCAAATTA
TTGCGTTCCTCCTTTTCCCTGCTATTAACAGGTGTCCTACTGGTGTGCGCTTGGATTTTTAACCGCTACTACTCCACTCA
CCAAGGACGCCGTCAGATCGATCGACTGAAGCTGAGAATCCCCCTATTCGGCAATCTGATCATCAAAACTGCCACCGCTC
AATTCTGCAGAATCTTCAGCTCATTGATCAGAGCAGGCGTACCAATCCTGATGTCACTAGAAATTGCCAGCGAAACCGCT
GGCAATGCGATCATTTCCGACGCCATTCTTGAATCACGCACCCTTGTGCAGGAAGGGGTACTCCTTAGTGCTGCCTTGAT
TCGCCAAAAAGTACTTCCAGACATGGCCTTAAACATGCTGGCCATTGGCGAGGAAACCGGAGAGATGGATCAAATGCTCA
GCAAGGTGGCTGATTTTTACGAGGATGAGGTCTCTACCTCGGTGAAGGCTCTTACCTCAATGCTTGAACCAGCGATGATC
GTTGTAGTGGGTGTCATCGTGGGCTCCATCCTGCTAGCGATGTATCTCCCCATGTTCACCGTGTTTGATCAGATCCAGTA
G

Upstream 100 bases:

>100_bases
AAACAGGGTGAAATTAGCCGTTCAGAAGCCATCGCCAAAGCCAGTAAACCCAGCGAACTGGAGCAACTCCTCAACGATGG
CTAAGAGACAGGCCTAAGCG

Downstream 100 bases:

>100_bases
CGAGCTGCAAACCCTTTGCAATGGCCTGACCAGCAAGCCAACCACTGGTCCAACAATGCTGGAAGTTGAACCCCCCCGTC
AGCCCATCCACATCGAGAAG

Product: pili biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTSFVATYESASGQTRTMTIKAADLTTAKKLLRRRGIRATDLKAALNNKGQESSKKIDRQKNTKSSNLGLFSIDLAAAFE
KSPGVKDKAVFASKLATLVDAGVPIVRSLDLMANQQRLPMFKRALMKVSLDVNEGSAMGTAMRMWPKVFDQLSIAMVEAG
EAGGVLDESLKRLAKLLEDNARLKNQIKGALGYPITVLVIAILVFLGMTIFLIPTFAEIFEDLGAELPLFTQFMVDLSKL
LRSSFSLLLTGVLLVCAWIFNRYYSTHQGRRQIDRLKLRIPLFGNLIIKTATAQFCRIFSSLIRAGVPILMSLEIASETA
GNAIISDAILESRTLVQEGVLLSAALIRQKVLPDMALNMLAIGEETGEMDQMLSKVADFYEDEVSTSVKALTSMLEPAMI
VVVGVIVGSILLAMYLPMFTVFDQIQ

Sequences:

>Translated_426_residues
MTSFVATYESASGQTRTMTIKAADLTTAKKLLRRRGIRATDLKAALNNKGQESSKKIDRQKNTKSSNLGLFSIDLAAAFE
KSPGVKDKAVFASKLATLVDAGVPIVRSLDLMANQQRLPMFKRALMKVSLDVNEGSAMGTAMRMWPKVFDQLSIAMVEAG
EAGGVLDESLKRLAKLLEDNARLKNQIKGALGYPITVLVIAILVFLGMTIFLIPTFAEIFEDLGAELPLFTQFMVDLSKL
LRSSFSLLLTGVLLVCAWIFNRYYSTHQGRRQIDRLKLRIPLFGNLIIKTATAQFCRIFSSLIRAGVPILMSLEIASETA
GNAIISDAILESRTLVQEGVLLSAALIRQKVLPDMALNMLAIGEETGEMDQMLSKVADFYEDEVSTSVKALTSMLEPAMI
VVVGVIVGSILLAMYLPMFTVFDQIQ
>Mature_425_residues
TSFVATYESASGQTRTMTIKAADLTTAKKLLRRRGIRATDLKAALNNKGQESSKKIDRQKNTKSSNLGLFSIDLAAAFEK
SPGVKDKAVFASKLATLVDAGVPIVRSLDLMANQQRLPMFKRALMKVSLDVNEGSAMGTAMRMWPKVFDQLSIAMVEAGE
AGGVLDESLKRLAKLLEDNARLKNQIKGALGYPITVLVIAILVFLGMTIFLIPTFAEIFEDLGAELPLFTQFMVDLSKLL
RSSFSLLLTGVLLVCAWIFNRYYSTHQGRRQIDRLKLRIPLFGNLIIKTATAQFCRIFSSLIRAGVPILMSLEIASETAG
NAIISDAILESRTLVQEGVLLSAALIRQKVLPDMALNMLAIGEETGEMDQMLSKVADFYEDEVSTSVKALTSMLEPAMIV
VVGVIVGSILLAMYLPMFTVFDQIQ

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=396, Percent_Identity=27.2727272727273, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786295, Length=341, Percent_Identity=29.6187683284457, Blast_Score=135, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 46674; Mature: 46543

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFVATYESASGQTRTMTIKAADLTTAKKLLRRRGIRATDLKAALNNKGQESSKKIDRQ
CCCHHEEHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHH
KNTKSSNLGLFSIDLAAAFEKSPGVKDKAVFASKLATLVDAGVPIVRSLDLMANQQRLPM
HCCCCCCCCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHH
FKRALMKVSLDVNEGSAMGTAMRMWPKVFDQLSIAMVEAGEAGGVLDESLKRLAKLLEDN
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ARLKNQIKGALGYPITVLVIAILVFLGMTIFLIPTFAEIFEDLGAELPLFTQFMVDLSKL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LRSSFSLLLTGVLLVCAWIFNRYYSTHQGRRQIDRLKLRIPLFGNLIIKTATAQFCRIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHH
SLIRAGVPILMSLEIASETAGNAIISDAILESRTLVQEGVLLSAALIRQKVLPDMALNML
HHHHCCCCCEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGEETGEMDQMLSKVADFYEDEVSTSVKALTSMLEPAMIVVVGVIVGSILLAMYLPMFT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFDQIQ
HHHCCC
>Mature Secondary Structure 
TSFVATYESASGQTRTMTIKAADLTTAKKLLRRRGIRATDLKAALNNKGQESSKKIDRQ
CCHHEEHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHH
KNTKSSNLGLFSIDLAAAFEKSPGVKDKAVFASKLATLVDAGVPIVRSLDLMANQQRLPM
HCCCCCCCCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHH
FKRALMKVSLDVNEGSAMGTAMRMWPKVFDQLSIAMVEAGEAGGVLDESLKRLAKLLEDN
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ARLKNQIKGALGYPITVLVIAILVFLGMTIFLIPTFAEIFEDLGAELPLFTQFMVDLSKL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LRSSFSLLLTGVLLVCAWIFNRYYSTHQGRRQIDRLKLRIPLFGNLIIKTATAQFCRIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHH
SLIRAGVPILMSLEIASETAGNAIISDAILESRTLVQEGVLLSAALIRQKVLPDMALNML
HHHHCCCCCEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGEETGEMDQMLSKVADFYEDEVSTSVKALTSMLEPAMIVVVGVIVGSILLAMYLPMFT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFDQIQ
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]