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The map label for this gene is alr [H]

Identifier: 161407967

GI number: 161407967

Start: 1629295

End: 1630503

Strand: Reverse

Name: alr [H]

Synonym: NATL1_19731

Alternate gene names: 161407967

Gene position: 1630503-1629295 (Counterclockwise)

Preceding gene: 124026680

Following gene: 124026674

Centisome position: 87.44

GC content: 36.31

Gene sequence:

>1209_bases
ATGCAGAGTATGTCAAAAATCAATAGAAGTGAGAGATCTTTCACTTTTGGTGGGTTAACTGAAAATGTAATTAGCCCTGA
TCCTCGCAGTCGTGCATGGGTTGAGGTCGATTCGAAAATTATCGAAAATAATGCAAGAGTTTTGAAAAACTTTATTGGCG
ATGATTGTTCATTGATGGCAGTTGTGAAAGCTGATGGATACGGACATGGTGCAGAGACTGTTGCTAAATCTGCGTTAACT
GGAGGTGCAGATAGTCTTGGAGTAGCAACTTTAGAAGAGGGTATTCAATTAAGGAATGCTGGCTTGAAGTGTCAGATATT
AATTCTTGGAAATCTAATTAATTCAGAAGAACTTTATTCTTCCTTTTGCTGGGATCTTATTCCTACGATTAGTGGAATTC
GTGAGGCAATAATTTGCAATAATATCGCTGAAAATAAGCATAAAAAATTTTTTATTCACTTAAAAGTTGATACGGGTATG
ACGAGACTTGGCTGTGATTGTGATGAAGTAAAAGACTTGATTTCTAAAATTGATTATTTAGAAAATATATCCCTAAAGGG
TATATATAGTCATTTAGCAATTGCTGATAAAGATTTAGAGAAGAATACAAAACTAAATTTTACACAAATTCAGGTAACTA
GATTTGAAAAGGTTTTAAAGGATTTGGGTGCTAGAAATAAGTCTTTATGTAGACACCTTGCAAATTCTGCGGGGACTCTT
TCAGATAGTCGTCTTCATTTTGACATGGTTCGAGTAGGACTAAGCTTATATGGTTATTTTCCTGTAAATGATTTTGAGTC
TGATTTGAGACTTAAACCTGCCTTGAAGGTCAAGTCTCGAGTTACTTTGGTTAGGGAGGTAGAAAAAGGAATAGGAGTGG
GGTATGGACATTTTTTTAAAACTCAAAGGAAAAGTAAACTTGCTGTAGTTGCTATTGGCTACGCAGATGGCGTCAGCAGA
AATCTTTCTGGGAAAATATCAGCCTCAATAGATGGGGTTTTGGTTCCCCAAGTAGGTGCAATTGCAATGGATCAAATGGT
TTTTGACATAACCGATAAACCAGATATTAGAACAGGTCAAGTTTTAACCCTTCTTGGTACTGATGGTGCAGTTTGTATTT
CACCCCAAAATTGGTGTGATTTATCTGGATCAATTCCATGGGAAGTTCTTTGTGGTTTCAGAAATCGTCTTCCTCGAGTT
GTCACTTAA

Upstream 100 bases:

>100_bases
CGCATTCAAAACAAGAACTTGACCCATGCAAGCAAGCTATTTAAGCGGCATGCTAGTGGTATTAACTCCTTGTTGCAGTT
TCCCTTATTACATTGATTGG

Downstream 100 bases:

>100_bases
AATTTGTAGAGGAGCACAATCTAATTTTTTTGAGCTCTGACTTGATAAGGTATTGGCAATGGAGAGGTGGCTGAGTGGTT
GAAAGCGGCTCCCTGCTAAG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MQSMSKINRSERSFTFGGLTENVISPDPRSRAWVEVDSKIIENNARVLKNFIGDDCSLMAVVKADGYGHGAETVAKSALT
GGADSLGVATLEEGIQLRNAGLKCQILILGNLINSEELYSSFCWDLIPTISGIREAIICNNIAENKHKKFFIHLKVDTGM
TRLGCDCDEVKDLISKIDYLENISLKGIYSHLAIADKDLEKNTKLNFTQIQVTRFEKVLKDLGARNKSLCRHLANSAGTL
SDSRLHFDMVRVGLSLYGYFPVNDFESDLRLKPALKVKSRVTLVREVEKGIGVGYGHFFKTQRKSKLAVVAIGYADGVSR
NLSGKISASIDGVLVPQVGAIAMDQMVFDITDKPDIRTGQVLTLLGTDGAVCISPQNWCDLSGSIPWEVLCGFRNRLPRV
VT

Sequences:

>Translated_402_residues
MQSMSKINRSERSFTFGGLTENVISPDPRSRAWVEVDSKIIENNARVLKNFIGDDCSLMAVVKADGYGHGAETVAKSALT
GGADSLGVATLEEGIQLRNAGLKCQILILGNLINSEELYSSFCWDLIPTISGIREAIICNNIAENKHKKFFIHLKVDTGM
TRLGCDCDEVKDLISKIDYLENISLKGIYSHLAIADKDLEKNTKLNFTQIQVTRFEKVLKDLGARNKSLCRHLANSAGTL
SDSRLHFDMVRVGLSLYGYFPVNDFESDLRLKPALKVKSRVTLVREVEKGIGVGYGHFFKTQRKSKLAVVAIGYADGVSR
NLSGKISASIDGVLVPQVGAIAMDQMVFDITDKPDIRTGQVLTLLGTDGAVCISPQNWCDLSGSIPWEVLCGFRNRLPRV
VT
>Mature_402_residues
MQSMSKINRSERSFTFGGLTENVISPDPRSRAWVEVDSKIIENNARVLKNFIGDDCSLMAVVKADGYGHGAETVAKSALT
GGADSLGVATLEEGIQLRNAGLKCQILILGNLINSEELYSSFCWDLIPTISGIREAIICNNIAENKHKKFFIHLKVDTGM
TRLGCDCDEVKDLISKIDYLENISLKGIYSHLAIADKDLEKNTKLNFTQIQVTRFEKVLKDLGARNKSLCRHLANSAGTL
SDSRLHFDMVRVGLSLYGYFPVNDFESDLRLKPALKVKSRVTLVREVEKGIGVGYGHFFKTQRKSKLAVVAIGYADGVSR
NLSGKISASIDGVLVPQVGAIAMDQMVFDITDKPDIRTGQVLTLLGTDGAVCISPQNWCDLSGSIPWEVLCGFRNRLPRV
VT

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=368, Percent_Identity=27.445652173913, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790487, Length=345, Percent_Identity=29.5652173913043, Blast_Score=138, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 44163; Mature: 44163

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSMSKINRSERSFTFGGLTENVISPDPRSRAWVEVDSKIIENNARVLKNFIGDDCSLMA
CCCHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEE
VVKADGYGHGAETVAKSALTGGADSLGVATLEEGIQLRNAGLKCQILILGNLINSEELYS
EEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHCHHHHCCCCEEEEEEECCCCCHHHHHH
SFCWDLIPTISGIREAIICNNIAENKHKKFFIHLKVDTGMTRLGCDCDEVKDLISKIDYL
HHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEEEEEECCCCHHCCCCHHHHHHHHHHHHHH
ENISLKGIYSHLAIADKDLEKNTKLNFTQIQVTRFEKVLKDLGARNKSLCRHLANSAGTL
HCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
SDSRLHFDMVRVGLSLYGYFPVNDFESDLRLKPALKVKSRVTLVREVEKGIGVGYGHFFK
CCCHHHHHHHHHHHHHEEEECCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCCHHHHHH
TQRKSKLAVVAIGYADGVSRNLSGKISASIDGVLVPQVGAIAMDQMVFDITDKPDIRTGQ
HCCCCCEEEEEEECCCCCCCCCCCEEECCCCEEECCCCCHHHHHHHHEECCCCCCCCCCC
VLTLLGTDGAVCISPQNWCDLSGSIPWEVLCGFRNRLPRVVT
EEEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQSMSKINRSERSFTFGGLTENVISPDPRSRAWVEVDSKIIENNARVLKNFIGDDCSLMA
CCCHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEE
VVKADGYGHGAETVAKSALTGGADSLGVATLEEGIQLRNAGLKCQILILGNLINSEELYS
EEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHCHHHHCCCCEEEEEEECCCCCHHHHHH
SFCWDLIPTISGIREAIICNNIAENKHKKFFIHLKVDTGMTRLGCDCDEVKDLISKIDYL
HHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEEEEEECCCCHHCCCCHHHHHHHHHHHHHH
ENISLKGIYSHLAIADKDLEKNTKLNFTQIQVTRFEKVLKDLGARNKSLCRHLANSAGTL
HCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
SDSRLHFDMVRVGLSLYGYFPVNDFESDLRLKPALKVKSRVTLVREVEKGIGVGYGHFFK
CCCHHHHHHHHHHHHHEEEECCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCCHHHHHH
TQRKSKLAVVAIGYADGVSRNLSGKISASIDGVLVPQVGAIAMDQMVFDITDKPDIRTGQ
HCCCCCEEEEEEECCCCCCCCCCCEEECCCCEEECCCCCHHHHHHHHEECCCCCCCCCCC
VLTLLGTDGAVCISPQNWCDLSGSIPWEVLCGFRNRLPRVVT
EEEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]