Click here to switch to the map view.

The map label for this gene is aroE [H]

Identifier: 124026892

GI number: 124026892

Start: 1848441

End: 1849376

Strand: Direct

Name: aroE [H]

Synonym: NATL1_21871

Alternate gene names: 124026892

Gene position: 1848441-1849376 (Clockwise)

Preceding gene: 124026890

Following gene: 124026893

Centisome position: 99.13

GC content: 33.44

Gene sequence:

>936_bases
GTGGTTCCCGAACAGTCTCTTAGCAAATTTGAATCAACATCATCAAAAATGAGCACTATCACTGGAAAAACTAATCTTGT
AGGGCTTCTTGGACAACCAGTAAATCATTCGCTGTCACCAATTATGCACAATGCCGCATATGAAGAAATGGGACTTGACT
GGTGTTATGTGGCGATGCCTTGCCACAGTCAAGATTTAGAGAAAGTCACAAAAGCATTAAGGTTTTTAGACTTTAAAGGC
TTGAATATAACTATTCCCCATAAGCAAGAGGTATTAAAAGCTTGCAACAAATTAACTGAAATTGCAAATGATATCCAAGC
AGTTAATACACTTATACCTGAAAAAAATAATCAATGGATAGGCGCAAACACTGATGTACAAGGATTCTTGACGCCATTAA
AAGATCATAATTTAAAAAATAAAAGTGTAGTTGTAATAGGCTGCGGGGGCAGCGCTAGAGCGGTAGTAATGGGATTAAGC
AGTTTAAATATTAAAAAAGTAACAATAATTAGCAGGAACGAAAAAACATTAAATATTTTTGTACAAAGCACGAGTAATTT
ATTATCAAAAAGAGATATATCAATTGAAAGTATTAATAATACAAAATTAAATGTTTTACCATACATACAAGAAGCCGATT
TAATTATTAATACAACTCCAATAGGGATGAATGGCAGTCAAGCTAAACAAGAAAGTGTTCCTCTTGGTCATGAAGTATGG
GACTGTCTTTCTAACAAAACTATTTTATACGATTTGATTTATACTCCTAGACCAACAAACTGGTTAAAAATTGGTCAACA
AAAAAATTGTTTTACCATTGACGGATTGGATATGCTTGTCGAACAAGGAGCTTTTTCAATAAAACTTTGGACTGGTTTTC
ATGACGTACCGGTTCAGACAATGAAATCATCTGCAGAAAAACATTTAATGGTTTAA

Upstream 100 bases:

>100_bases
GTCCCTAGATCGATTCCGACAACCTTCCCCATGGGTGAGTAGCTCCTAATTTCTTTCTTTAGGTCATATCCTCGTCAGTG
AATCCTATTTGAGGCGAGGC

Downstream 100 bases:

>100_bases
TCTAAAAAAAATGTAATTGGTTATGCCTTCACTAGGAGCAAGATTATTAGGGGTTCTTCTGTATATGATTCCATGGTCTG
ATTCGCTTACTTTTGGCAAT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MVPEQSLSKFESTSSKMSTITGKTNLVGLLGQPVNHSLSPIMHNAAYEEMGLDWCYVAMPCHSQDLEKVTKALRFLDFKG
LNITIPHKQEVLKACNKLTEIANDIQAVNTLIPEKNNQWIGANTDVQGFLTPLKDHNLKNKSVVVIGCGGSARAVVMGLS
SLNIKKVTIISRNEKTLNIFVQSTSNLLSKRDISIESINNTKLNVLPYIQEADLIINTTPIGMNGSQAKQESVPLGHEVW
DCLSNKTILYDLIYTPRPTNWLKIGQQKNCFTIDGLDMLVEQGAFSIKLWTGFHDVPVQTMKSSAEKHLMV

Sequences:

>Translated_311_residues
MVPEQSLSKFESTSSKMSTITGKTNLVGLLGQPVNHSLSPIMHNAAYEEMGLDWCYVAMPCHSQDLEKVTKALRFLDFKG
LNITIPHKQEVLKACNKLTEIANDIQAVNTLIPEKNNQWIGANTDVQGFLTPLKDHNLKNKSVVVIGCGGSARAVVMGLS
SLNIKKVTIISRNEKTLNIFVQSTSNLLSKRDISIESINNTKLNVLPYIQEADLIINTTPIGMNGSQAKQESVPLGHEVW
DCLSNKTILYDLIYTPRPTNWLKIGQQKNCFTIDGLDMLVEQGAFSIKLWTGFHDVPVQTMKSSAEKHLMV
>Mature_311_residues
MVPEQSLSKFESTSSKMSTITGKTNLVGLLGQPVNHSLSPIMHNAAYEEMGLDWCYVAMPCHSQDLEKVTKALRFLDFKG
LNITIPHKQEVLKACNKLTEIANDIQAVNTLIPEKNNQWIGANTDVQGFLTPLKDHNLKNKSVVVIGCGGSARAVVMGLS
SLNIKKVTIISRNEKTLNIFVQSTSNLLSKRDISIESINNTKLNVLPYIQEADLIINTTPIGMNGSQAKQESVPLGHEVW
DCLSNKTILYDLIYTPRPTNWLKIGQQKNCFTIDGLDMLVEQGAFSIKLWTGFHDVPVQTMKSSAEKHLMV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=290, Percent_Identity=27.5862068965517, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789675, Length=271, Percent_Identity=30.2583025830258, Blast_Score=100, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=284, Percent_Identity=29.5774647887324, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 34479; Mature: 34479

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPEQSLSKFESTSSKMSTITGKTNLVGLLGQPVNHSLSPIMHNAAYEEMGLDWCYVAMP
CCCHHHHHHHHHCCHHHHEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
CHSQDLEKVTKALRFLDFKGLNITIPHKQEVLKACNKLTEIANDIQAVNTLIPEKNNQWI
CCCHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
GANTDVQGFLTPLKDHNLKNKSVVVIGCGGSARAVVMGLSSLNIKKVTIISRNEKTLNIF
CCCCCHHHHCCCHHCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEEECCCCEEEEE
VQSTSNLLSKRDISIESINNTKLNVLPYIQEADLIINTTPIGMNGSQAKQESVPLGHEVW
EECHHHHHHHCCCEEEECCCCEEEEEECEECCCEEEECCCCCCCCCCCHHHCCCCCHHHH
DCLSNKTILYDLIYTPRPTNWLKIGQQKNCFTIDGLDMLVEQGAFSIKLWTGFHDVPVQT
HHHCCCEEEEEEEECCCCCCCEEECCCCCCEEECCHHHHHHCCCEEEEEECCCCCCCHHH
MKSSAEKHLMV
HHCCHHHCCCC
>Mature Secondary Structure
MVPEQSLSKFESTSSKMSTITGKTNLVGLLGQPVNHSLSPIMHNAAYEEMGLDWCYVAMP
CCCHHHHHHHHHCCHHHHEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
CHSQDLEKVTKALRFLDFKGLNITIPHKQEVLKACNKLTEIANDIQAVNTLIPEKNNQWI
CCCHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
GANTDVQGFLTPLKDHNLKNKSVVVIGCGGSARAVVMGLSSLNIKKVTIISRNEKTLNIF
CCCCCHHHHCCCHHCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEEECCCCEEEEE
VQSTSNLLSKRDISIESINNTKLNVLPYIQEADLIINTTPIGMNGSQAKQESVPLGHEVW
EECHHHHHHHCCCEEEECCCCEEEEEECEECCCEEEECCCCCCCCCCCHHHCCCCCHHHH
DCLSNKTILYDLIYTPRPTNWLKIGQQKNCFTIDGLDMLVEQGAFSIKLWTGFHDVPVQT
HHHCCCEEEEEEEECCCCCCCEEECCCCCCEEECCHHHHHHCCCEEEEEECCCCCCCHHH
MKSSAEKHLMV
HHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA