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The map label for this gene is rnhB

Identifier: 124026648

GI number: 124026648

Start: 1596757

End: 1597344

Strand: Direct

Name: rnhB

Synonym: NATL1_19431

Alternate gene names: 124026648

Gene position: 1596757-1597344 (Clockwise)

Preceding gene: 124026647

Following gene: 124026650

Centisome position: 85.63

GC content: 37.59

Gene sequence:

>588_bases
ATGGAAGATATAAAATCTCTTATCGCTGGAGTTGATGAAGTGGGAAAAGGTTGTTTATTTGGCCCTGTTTTCGCGGCAGC
AGTTATTTTAAGCAAAGAAAATGAAATAGAGCTCTTAAATCAAGGGTTGAAAGACAGTAAAAAATTAAGTCATCGACAAA
GACATAACTTAGTTCCTTTGATAAAAACAAACTCAATAGCCTGGACAATTGGCCAAGCTTCAGCAAGAGAAATAGACGTT
ATCGGCATCCGAGATGCTACTGAGAAAGCCATGCTAAGAGCATTAGAAAAATTTTCATCTCCACCAGACTTAATCCTTGT
AGACGGAATTCTACCCATTCGCTTGTGGCCAGGGAAACAAAAGACACAAGTTCGAGGTGAAAGTCATTTTGCTTCAATTG
CTGCTGCAAGTGTATTAGCGAAAGAAACCAGGGATGAATTAATTAAACGACTAGCTCGCAAATACAATTGTTATGGACTA
GAAAAAAACAAGGGGTATGGAACTGAGATCCATAGAACAAACTTAATCAAAGAAGGTGCAACAAAACTCCACCGAAAAAG
TTTTATCTCACGATTGGAAATAAATTGA

Upstream 100 bases:

>100_bases
ATTCAATAAGCGAAAAGAATGAATTACCTTCCACCGATTCACAAGAAGTTAATGAGGATCCAAGACGAAAAAGAAGAAGG
TCTTCAGCCTCTTCTTAAAT

Downstream 100 bases:

>100_bases
TATTTATTTTGTAACTAATTTTCTTTACACCAATTATTAAAATCAACAATTAGCTGCTTCTGAACCCTTGCCTTAATTCC
TAACAAAATACCATTCAATA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MEDIKSLIAGVDEVGKGCLFGPVFAAAVILSKENEIELLNQGLKDSKKLSHRQRHNLVPLIKTNSIAWTIGQASAREIDV
IGIRDATEKAMLRALEKFSSPPDLILVDGILPIRLWPGKQKTQVRGESHFASIAAASVLAKETRDELIKRLARKYNCYGL
EKNKGYGTEIHRTNLIKEGATKLHRKSFISRLEIN

Sequences:

>Translated_195_residues
MEDIKSLIAGVDEVGKGCLFGPVFAAAVILSKENEIELLNQGLKDSKKLSHRQRHNLVPLIKTNSIAWTIGQASAREIDV
IGIRDATEKAMLRALEKFSSPPDLILVDGILPIRLWPGKQKTQVRGESHFASIAAASVLAKETRDELIKRLARKYNCYGL
EKNKGYGTEIHRTNLIKEGATKLHRKSFISRLEIN
>Mature_195_residues
MEDIKSLIAGVDEVGKGCLFGPVFAAAVILSKENEIELLNQGLKDSKKLSHRQRHNLVPLIKTNSIAWTIGQASAREIDV
IGIRDATEKAMLRALEKFSSPPDLILVDGILPIRLWPGKQKTQVRGESHFASIAAASVLAKETRDELIKRLARKYNCYGL
EKNKGYGTEIHRTNLIKEGATKLHRKSFISRLEIN

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=182, Percent_Identity=42.8571428571429, Blast_Score=128, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_PROM1 (A2C4T9)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015763.1
- ProteinModelPortal:   A2C4T9
- SMR:   A2C4T9
- STRING:   A2C4T9
- GeneID:   4779496
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_19431
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   IICGVDE
- ProtClustDB:   PRK13925
- BioCyc:   PMAR167555:NATL1_19431-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 21710; Mature: 21710

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDIKSLIAGVDEVGKGCLFGPVFAAAVILSKENEIELLNQGLKDSKKLSHRQRHNLVPL
CHHHHHHHHCHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCCE
IKTNSIAWTIGQASAREIDVIGIRDATEKAMLRALEKFSSPPDLILVDGILPIRLWPGKQ
EECCCEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCC
KTQVRGESHFASIAAASVLAKETRDELIKRLARKYNCYGLEKNKGYGTEIHRTNLIKEGA
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
TKLHRKSFISRLEIN
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MEDIKSLIAGVDEVGKGCLFGPVFAAAVILSKENEIELLNQGLKDSKKLSHRQRHNLVPL
CHHHHHHHHCHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCCE
IKTNSIAWTIGQASAREIDVIGIRDATEKAMLRALEKFSSPPDLILVDGILPIRLWPGKQ
EECCCEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCC
KTQVRGESHFASIAAASVLAKETRDELIKRLARKYNCYGLEKNKGYGTEIHRTNLIKEGA
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
TKLHRKSFISRLEIN
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA