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The map label for this gene is putP [H]

Identifier: 124026586

GI number: 124026586

Start: 1537222

End: 1538973

Strand: Reverse

Name: putP [H]

Synonym: NATL1_18811

Alternate gene names: 124026586

Gene position: 1538973-1537222 (Counterclockwise)

Preceding gene: 124026587

Following gene: 124026585

Centisome position: 82.53

GC content: 39.16

Gene sequence:

>1752_bases
ATGACATTAATTGATTGGTTTATTTTATTTGTTTATTTGATCTTTTCCTTGGTATTGGGAATTTATATATCTCTAAAAAA
TCATAATGAAGCAGACTATTTTGTTGCTGGTCGTCGTCTTAATGGATTGCTTGCAGGTATGTCTATGGCTGCAACAACGT
TTTCGATTGACACACCTCTTTATGTGGCCGGAGTTATTGGGACTCGAGGCTTGGCAGGAAACTGGGAGTGGTGGAGTTTT
GGCCTTGCTCATGTTGCTATGACGGTTATATTCGCTCCACTGTGGAGGCGTAGTGGAGTATTGACTGACGCAGCCTTTAC
TGAATTACGTTATGGGGGGCAAGCAGCAGCTTACTTAAGAGGTATAAAAGCTTTTTTACTCTCAGTTCCAATCAATTGTA
TTGGGATTGGTTATGCTTTCTTAGCAATGCGTAAAGTGGCTGAATCATTAGGTGTGGTAGATGGACATATTGTTTTCGGA
CCCTTTACTGACACGATACTTTTAATGATTTTAGTTGCTTTGTTTTTGCTTGTTTACACTGTACTAGGCGGGCTTTGGGC
AGTAGTCGTTAATGATTTTGTACAACTTGTATTAGCTCTTTTAGGCGCATTTGCTGTTTGCTTTGTGGCACTTGATGCTT
CAGGTGGTATGACGAATTTGTTAACAAAGTTAGAGGCATTAGATCGACCTGAGCTGCTTTCTTTATTTCCATGGACATTA
AGTAAAAATGGTTTCAATTGGTTGGATAGCTCAGGAATAAGTATTACTACTTTCTTCGCTTTTATTTCTTTGCAGTGGTG
GAGTTTCAGACGTAGTGATGGTGGTGGGGAATTTATTCAACGTTTATTGGCTACAAAAGATGAAAAACAAGCAACTTTGG
CAGGAATAGTTTTTTTAATTGTTAATTATCTTGTTCGCAGTTGGCTTTGGATTTTAGTTGGCTTAGCTGGTTTAGTCCTC
TTGCCTCAACAAACTGACTGGGAATTAAGTTATCCAAACCTTGCTGTTACATACTTACCACCCGTTGGACTTGGATTAGT
CGTGGTTTCATTGGTCGCTGCATTTATGAGCACCGTAAGCACCTCAATCAATTGGGGGGCAAGTTATCTTGCACATGATC
TTTATAAAAGATTTGTGAGGCCATTTGCTGGGCCTAGAGAAATGATTTTTATGGGCCAGCTAGCAAGTATTTTGTTGCTT
CTAATTGGAGTCCTCACGGCTTTATTTAGTAACAGTATTGGTTCAATGTTTAGACTTGTTATTGCGATAGGTACAGGACC
AGGTGCCGTTCTTGTACTTAGATGGTTTTGGTGGCGAATTAATGCTCTAGTAGAACTTTCGGCAATGTTAAGTGGCTTTT
TTATAGGATTAATCACTTCCGTTTCTCCTTCGTTAACAATTGAAGATTTCGGAAAAAGACTTATATTCACAACTTCATTC
TCGGCAGTGATTTGGTTGCTTACTTTATTTTTTACTGAGCCAGAGTCTGACGAGACACTCAATAACTTTGTAATGCAGGT
AAAACCTCCAGGCCCTGGCTGGAGCAAAATACGGAAGAAATTGAATATTGATCCAGTTGATTCTTTTTTAGCGCTTGGAT
GTCGCTTCATTTTAGGCTCAGGTATTCTTTATGGAGGCTTACTCAGTATTGGAGCTTTCTTATTACATCAAGAAAGGAGC
GCTTGGATTGCACTCTCCATTGCGGTCAGTTCTGTGTTTTTAATGAAGAAAACAAGACTAATAACTCAATAA

Upstream 100 bases:

>100_bases
AGGTAGAGATAAAGATGCGGCATGTGGACAATTAAGAAGGCAAACAATCGATAAAATAAAAATCAACTAAGCAGGAAACA
TATATGTCTTGTGGACTCTT

Downstream 100 bases:

>100_bases
GTTGACGCTAAATAGCCAAATGGTCAAAATTTAGAGCAGAATGAAATTCTAATTCACTTGCAACCTTGGGTTTCTTACGG
ACAACTCTTTTTCCTATCTT

Product: sodium/solute symporter family protein glucose transporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MTLIDWFILFVYLIFSLVLGIYISLKNHNEADYFVAGRRLNGLLAGMSMAATTFSIDTPLYVAGVIGTRGLAGNWEWWSF
GLAHVAMTVIFAPLWRRSGVLTDAAFTELRYGGQAAAYLRGIKAFLLSVPINCIGIGYAFLAMRKVAESLGVVDGHIVFG
PFTDTILLMILVALFLLVYTVLGGLWAVVVNDFVQLVLALLGAFAVCFVALDASGGMTNLLTKLEALDRPELLSLFPWTL
SKNGFNWLDSSGISITTFFAFISLQWWSFRRSDGGGEFIQRLLATKDEKQATLAGIVFLIVNYLVRSWLWILVGLAGLVL
LPQQTDWELSYPNLAVTYLPPVGLGLVVVSLVAAFMSTVSTSINWGASYLAHDLYKRFVRPFAGPREMIFMGQLASILLL
LIGVLTALFSNSIGSMFRLVIAIGTGPGAVLVLRWFWWRINALVELSAMLSGFFIGLITSVSPSLTIEDFGKRLIFTTSF
SAVIWLLTLFFTEPESDETLNNFVMQVKPPGPGWSKIRKKLNIDPVDSFLALGCRFILGSGILYGGLLSIGAFLLHQERS
AWIALSIAVSSVFLMKKTRLITQ

Sequences:

>Translated_583_residues
MTLIDWFILFVYLIFSLVLGIYISLKNHNEADYFVAGRRLNGLLAGMSMAATTFSIDTPLYVAGVIGTRGLAGNWEWWSF
GLAHVAMTVIFAPLWRRSGVLTDAAFTELRYGGQAAAYLRGIKAFLLSVPINCIGIGYAFLAMRKVAESLGVVDGHIVFG
PFTDTILLMILVALFLLVYTVLGGLWAVVVNDFVQLVLALLGAFAVCFVALDASGGMTNLLTKLEALDRPELLSLFPWTL
SKNGFNWLDSSGISITTFFAFISLQWWSFRRSDGGGEFIQRLLATKDEKQATLAGIVFLIVNYLVRSWLWILVGLAGLVL
LPQQTDWELSYPNLAVTYLPPVGLGLVVVSLVAAFMSTVSTSINWGASYLAHDLYKRFVRPFAGPREMIFMGQLASILLL
LIGVLTALFSNSIGSMFRLVIAIGTGPGAVLVLRWFWWRINALVELSAMLSGFFIGLITSVSPSLTIEDFGKRLIFTTSF
SAVIWLLTLFFTEPESDETLNNFVMQVKPPGPGWSKIRKKLNIDPVDSFLALGCRFILGSGILYGGLLSIGAFLLHQERS
AWIALSIAVSSVFLMKKTRLITQ
>Mature_582_residues
TLIDWFILFVYLIFSLVLGIYISLKNHNEADYFVAGRRLNGLLAGMSMAATTFSIDTPLYVAGVIGTRGLAGNWEWWSFG
LAHVAMTVIFAPLWRRSGVLTDAAFTELRYGGQAAAYLRGIKAFLLSVPINCIGIGYAFLAMRKVAESLGVVDGHIVFGP
FTDTILLMILVALFLLVYTVLGGLWAVVVNDFVQLVLALLGAFAVCFVALDASGGMTNLLTKLEALDRPELLSLFPWTLS
KNGFNWLDSSGISITTFFAFISLQWWSFRRSDGGGEFIQRLLATKDEKQATLAGIVFLIVNYLVRSWLWILVGLAGLVLL
PQQTDWELSYPNLAVTYLPPVGLGLVVVSLVAAFMSTVSTSINWGASYLAHDLYKRFVRPFAGPREMIFMGQLASILLLL
IGVLTALFSNSIGSMFRLVIAIGTGPGAVLVLRWFWWRINALVELSAMLSGFFIGLITSVSPSLTIEDFGKRLIFTTSFS
AVIWLLTLFFTEPESDETLNNFVMQVKPPGPGWSKIRKKLNIDPVDSFLALGCRFILGSGILYGGLLSIGAFLLHQERSA
WIALSIAVSSVFLMKKTRLITQ

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI109659836, Length=493, Percent_Identity=24.5436105476673, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4507035, Length=446, Percent_Identity=24.6636771300448, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI14140236, Length=506, Percent_Identity=21.7391304347826, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI109659839, Length=509, Percent_Identity=23.9685658153242, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790113, Length=519, Percent_Identity=22.5433526011561, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082237, Length=488, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 64141; Mature: 64009

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLIDWFILFVYLIFSLVLGIYISLKNHNEADYFVAGRRLNGLLAGMSMAATTFSIDTPL
CHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEECHHHHHHHHHHHHHHHEEECCCCH
YVAGVIGTRGLAGNWEWWSFGLAHVAMTVIFAPLWRRSGVLTDAAFTELRYGGQAAAYLR
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHH
GIKAFLLSVPINCIGIGYAFLAMRKVAESLGVVDGHIVFGPFTDTILLMILVALFLLVYT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHH
VLGGLWAVVVNDFVQLVLALLGAFAVCFVALDASGGMTNLLTKLEALDRPELLSLFPWTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHCCHHH
SKNGFNWLDSSGISITTFFAFISLQWWSFRRSDGGGEFIQRLLATKDEKQATLAGIVFLI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
VNYLVRSWLWILVGLAGLVLLPQQTDWELSYPNLAVTYLPPVGLGLVVVSLVAAFMSTVS
HHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
TSINWGASYLAHDLYKRFVRPFAGPREMIFMGQLASILLLLIGVLTALFSNSIGSMFRLV
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAIGTGPGAVLVLRWFWWRINALVELSAMLSGFFIGLITSVSPSLTIEDFGKRLIFTTSF
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEEECCH
SAVIWLLTLFFTEPESDETLNNFVMQVKPPGPGWSKIRKKLNIDPVDSFLALGCRFILGS
HHHHHHHHHHHCCCCCCCHHHHCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHC
GILYGGLLSIGAFLLHQERSAWIALSIAVSSVFLMKKTRLITQ
HHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLIDWFILFVYLIFSLVLGIYISLKNHNEADYFVAGRRLNGLLAGMSMAATTFSIDTPL
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEECHHHHHHHHHHHHHHHEEECCCCH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HHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]