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The map label for this gene is bioD [H]

Identifier: 124026576

GI number: 124026576

Start: 1530485

End: 1531135

Strand: Direct

Name: bioD [H]

Synonym: NATL1_18711

Alternate gene names: 124026576

Gene position: 1530485-1531135 (Clockwise)

Preceding gene: 124026575

Following gene: 124026577

Centisome position: 82.08

GC content: 36.56

Gene sequence:

>651_bases
ATGAGTACTTTCTCTAAAAGAATTATCATTTGTGGTACAGATACAGATGTAGGTAAAACGATAGTTAGTAGTTTTCTCGT
CCAAGGTCTTAAAGGTATCTACTGGAAACCCATTCAAAGTGGAACAGAGGAAGGCACAGATACCAAAACTGTTTGCAATC
TCTTAAGTCTCGAACCTAACAGCTATCTTCCTGAAAGATATAAATTCAAGGCTCCTGTCTCTCCACATTGGGCTGCAGAA
CAAGAGTCTGCTTTTATTGAACCAAGTAATTTAAAATTACCTGACTTGGATAAATTAATAATTATAGAGACGGCAGGTGG
TTTAATGGTTCCTTTAAATCGAGATTGGCTACAAATAGACCAATTAAAGGCTTGGGGAGCTCCAATAATTCTTGTAGCCA
GAACCGGTCTTGGCACCCTCAATCACACCTTGTTAAGTCTAGAAGCCTTGAAAAATAGAAATTTAGACGTATTAGGAATA
GTATTAAACGGCCCTCCACATAAAGATAATCCGAAGACTCTAGAACAATTTGGAGATACTAAAATTCTTGCAAGTCTTCC
TATCTTTGACGAAGTCAACGCAAAAGTACTTTCACAAGAATGGCATAAACAGCAATTAGATCAAAAGCTTAAAAGATACA
TTCAAAACTAA

Upstream 100 bases:

>100_bases
GTGTTTCAGATTGGAGACATCTTTTATCTTTTTGGCCAATTTCCAACAAAGATCAACAAGTAAGCCTTAGTTGGTCAATT
CAGTTTTTATTAATAAAGCG

Downstream 100 bases:

>100_bases
AATTTTATTTTTTTCTTAATCAAAAGATTATTTTGACTTCAATCAAGTTAAATGAAACAAGAGGAAAAACTAAATTTGAT
GAATGAGAAAGAAAATTCAA

Product: putative dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSTFSKRIIICGTDTDVGKTIVSSFLVQGLKGIYWKPIQSGTEEGTDTKTVCNLLSLEPNSYLPERYKFKAPVSPHWAAE
QESAFIEPSNLKLPDLDKLIIIETAGGLMVPLNRDWLQIDQLKAWGAPIILVARTGLGTLNHTLLSLEALKNRNLDVLGI
VLNGPPHKDNPKTLEQFGDTKILASLPIFDEVNAKVLSQEWHKQQLDQKLKRYIQN

Sequences:

>Translated_216_residues
MSTFSKRIIICGTDTDVGKTIVSSFLVQGLKGIYWKPIQSGTEEGTDTKTVCNLLSLEPNSYLPERYKFKAPVSPHWAAE
QESAFIEPSNLKLPDLDKLIIIETAGGLMVPLNRDWLQIDQLKAWGAPIILVARTGLGTLNHTLLSLEALKNRNLDVLGI
VLNGPPHKDNPKTLEQFGDTKILASLPIFDEVNAKVLSQEWHKQQLDQKLKRYIQN
>Mature_215_residues
STFSKRIIICGTDTDVGKTIVSSFLVQGLKGIYWKPIQSGTEEGTDTKTVCNLLSLEPNSYLPERYKFKAPVSPHWAAEQ
ESAFIEPSNLKLPDLDKLIIIETAGGLMVPLNRDWLQIDQLKAWGAPIILVARTGLGTLNHTLLSLEALKNRNLDVLGIV
LNGPPHKDNPKTLEQFGDTKILASLPIFDEVNAKVLSQEWHKQQLDQKLKRYIQN

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=214, Percent_Identity=31.3084112149533, Blast_Score=87, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324385, Length=190, Percent_Identity=36.8421052631579, Blast_Score=104, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24141; Mature: 24010

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFSKRIIICGTDTDVGKTIVSSFLVQGLKGIYWKPIQSGTEEGTDTKTVCNLLSLEPN
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHCCCC
SYLPERYKFKAPVSPHWAAEQESAFIEPSNLKLPDLDKLIIIETAGGLMVPLNRDWLQID
CCCCCCEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHH
QLKAWGAPIILVARTGLGTLNHTLLSLEALKNRNLDVLGIVLNGPPHKDNPKTLEQFGDT
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHCCCC
KILASLPIFDEVNAKVLSQEWHKQQLDQKLKRYIQN
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STFSKRIIICGTDTDVGKTIVSSFLVQGLKGIYWKPIQSGTEEGTDTKTVCNLLSLEPN
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHCCCC
SYLPERYKFKAPVSPHWAAEQESAFIEPSNLKLPDLDKLIIIETAGGLMVPLNRDWLQID
CCCCCCEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHH
QLKAWGAPIILVARTGLGTLNHTLLSLEALKNRNLDVLGIVLNGPPHKDNPKTLEQFGDT
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHCCCC
KILASLPIFDEVNAKVLSQEWHKQQLDQKLKRYIQN
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA