Click here to switch to the map view.

The map label for this gene is gpmI

Identifier: 124026539

GI number: 124026539

Start: 1495847

End: 1497475

Strand: Direct

Name: gpmI

Synonym: NATL1_18341

Alternate gene names: 124026539

Gene position: 1495847-1497475 (Clockwise)

Preceding gene: 124026537

Following gene: 124026540

Centisome position: 80.22

GC content: 38.37

Gene sequence:

>1629_bases
ATGTCAGGCAGTAATCCAGCTGTTTCAATAAATAAAAGGAAAGTAGCACCAGTCGTGCTAGCGATACTTGATGGTTGGGG
CTATAGAGAAGAAATCGAACATAATGCGGTTAGACAAGCATCAACCCCTGTAATAGATGCCTTATGGCATGCCTATCCTC
ATACTCTTATTGAGGCTAGTGGTGCAGATGTTGGACTTCCAGATGAACAAATGGGTAACTCTGAAGTTGGTCATCTCACC
ATTGGAGCAGGGAGGATCATTCAGCAAGAGCTAGTTCGTATATCTAATACCGTAAAAGAAAATAAATTAATTACAAACCC
TGCTCTTAATCAATTTTCTCAATCCTTGAAAAAAGGTGGAGGAACTCTCCATATCATGGGACTTTGCTCTGATGGAGGAG
TTCACAGCCACATCAATCATTTATGTGGATTAATTGAATGGGCTGCAAGCAAGGGGCTAAAAAGTGTTTCATTGCATTTA
TTTACTGATGGGAGAGACACTTCAGCAAAAAGTGCGAATAAATATATAAACACGATAGAAGCTAAAATCAAGTCAACAGG
AGTAGGAGAAATTTCATCACTTTGCGGAAGATATTGGGCTATGGACCGAGATAATCGATGGGAAAGGACATCAAAAGCCT
ACGAATTGCTTACCGACCCAAGATTTGCCCTCAGCAAGCTATCTGCGGCAGAAAGTATAAATAAAAGCTATCAAGAAGGA
ATAACAGATGAATTTATAGAACCCGTTAGACTTTCCTCCTCGTTTTTAAAAGATGGAGATGGAGTAGTTTTTTTTAATTT
CCGTCCTGATAGAGCTAGGCAGTTAGTAAAGGCACTTAAATTAAAAGATTTTGATGGCTTTGAGAGGAAAAACAGAGCAG
ATATTGACGTTCTTACCTTTACACAATACGAATCAGGTCTTCCTGTATCAGTTGCCTTCCCACCTGAACCTCTAAATGAT
TTGTTAGGTCAAGTAATTTCTGATCATGGTTTAAATCAATATCGGACAGCTGAAACTGAAAAATATCCACACGTAACTTA
TTTTTTAAATGGAGGTATTGAAAAACCATTAAAAGGAGAAGTAAGACATCTCGTGCCTTCCCCAAGAGTTGCAACATACG
ATCTACAGCCCGAAATGTCAGCAGACGAATTGACAGATAGTTGTATCAAAGCAATTGACTCTGGAATTTACTCATTAGTG
GTAATCAATTTTGCTAATCCAGATATGGTTGGACATTCGGGAATAATGACAGCGGCAATAAAAGCTAATGAAAAAGTTGA
TAGCTGCGTTGGAAAATTATTAAATTCAATTGGAAAGTTAGGTGGATCTCTTCTCATAACAGCTGATCATGGTAATTCTG
AAATGATGATTGGTCCTGATGGACAACCATGGACCGCGCATACAACCAATCCTGTACCAGTTATACTTATCGAAGGCGAA
AAACGTAAATTGAGCGGATATGGTAATGATATAAAACTAAGACAGTCTGGTGGTGGATTAGCTGATCTAGCTCCTACTCT
TTTACACCTATTGAATCTACCAAAGCCAAAAGCAATGACTGGAAAAACTCTTATTGAGCCAATTAACTTACCTAAGAAAC
CAAATCTTATTCCTCAACCAGCATATTAA

Upstream 100 bases:

>100_bases
TAATAGGGAAAAGCTAACTAAACATCAAAGTATTAGCCTCTTTGCCAATTAGGAAGTAATTTAATACGAAAGAAACCCAC
CAAAGAAACAAATTTCTTTA

Downstream 100 bases:

>100_bases
AGTAAAACAATGATCATTCCTTTTTTATCTTGGGCTTGGGCAATTTCAGGAGTATTTCTAATACTATTAGTTCTTCTTCA
TAGCCCAAAAGGTGATGGAA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MSGSNPAVSINKRKVAPVVLAILDGWGYREEIEHNAVRQASTPVIDALWHAYPHTLIEASGADVGLPDEQMGNSEVGHLT
IGAGRIIQQELVRISNTVKENKLITNPALNQFSQSLKKGGGTLHIMGLCSDGGVHSHINHLCGLIEWAASKGLKSVSLHL
FTDGRDTSAKSANKYINTIEAKIKSTGVGEISSLCGRYWAMDRDNRWERTSKAYELLTDPRFALSKLSAAESINKSYQEG
ITDEFIEPVRLSSSFLKDGDGVVFFNFRPDRARQLVKALKLKDFDGFERKNRADIDVLTFTQYESGLPVSVAFPPEPLND
LLGQVISDHGLNQYRTAETEKYPHVTYFLNGGIEKPLKGEVRHLVPSPRVATYDLQPEMSADELTDSCIKAIDSGIYSLV
VINFANPDMVGHSGIMTAAIKANEKVDSCVGKLLNSIGKLGGSLLITADHGNSEMMIGPDGQPWTAHTTNPVPVILIEGE
KRKLSGYGNDIKLRQSGGGLADLAPTLLHLLNLPKPKAMTGKTLIEPINLPKKPNLIPQPAY

Sequences:

>Translated_542_residues
MSGSNPAVSINKRKVAPVVLAILDGWGYREEIEHNAVRQASTPVIDALWHAYPHTLIEASGADVGLPDEQMGNSEVGHLT
IGAGRIIQQELVRISNTVKENKLITNPALNQFSQSLKKGGGTLHIMGLCSDGGVHSHINHLCGLIEWAASKGLKSVSLHL
FTDGRDTSAKSANKYINTIEAKIKSTGVGEISSLCGRYWAMDRDNRWERTSKAYELLTDPRFALSKLSAAESINKSYQEG
ITDEFIEPVRLSSSFLKDGDGVVFFNFRPDRARQLVKALKLKDFDGFERKNRADIDVLTFTQYESGLPVSVAFPPEPLND
LLGQVISDHGLNQYRTAETEKYPHVTYFLNGGIEKPLKGEVRHLVPSPRVATYDLQPEMSADELTDSCIKAIDSGIYSLV
VINFANPDMVGHSGIMTAAIKANEKVDSCVGKLLNSIGKLGGSLLITADHGNSEMMIGPDGQPWTAHTTNPVPVILIEGE
KRKLSGYGNDIKLRQSGGGLADLAPTLLHLLNLPKPKAMTGKTLIEPINLPKKPNLIPQPAY
>Mature_541_residues
SGSNPAVSINKRKVAPVVLAILDGWGYREEIEHNAVRQASTPVIDALWHAYPHTLIEASGADVGLPDEQMGNSEVGHLTI
GAGRIIQQELVRISNTVKENKLITNPALNQFSQSLKKGGGTLHIMGLCSDGGVHSHINHLCGLIEWAASKGLKSVSLHLF
TDGRDTSAKSANKYINTIEAKIKSTGVGEISSLCGRYWAMDRDNRWERTSKAYELLTDPRFALSKLSAAESINKSYQEGI
TDEFIEPVRLSSSFLKDGDGVVFFNFRPDRARQLVKALKLKDFDGFERKNRADIDVLTFTQYESGLPVSVAFPPEPLNDL
LGQVISDHGLNQYRTAETEKYPHVTYFLNGGIEKPLKGEVRHLVPSPRVATYDLQPEMSADELTDSCIKAIDSGIYSLVV
INFANPDMVGHSGIMTAAIKANEKVDSCVGKLLNSIGKLGGSLLITADHGNSEMMIGPDGQPWTAHTTNPVPVILIEGEK
RKLSGYGNDIKLRQSGGGLADLAPTLLHLLNLPKPKAMTGKTLIEPINLPKKPNLIPQPAY

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=515, Percent_Identity=46.7961165048544, Blast_Score=496, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI32564249, Length=532, Percent_Identity=41.9172932330827, Blast_Score=417, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17507741, Length=532, Percent_Identity=41.9172932330827, Blast_Score=417, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_PROM1 (A2C4I0)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015654.1
- ProteinModelPortal:   A2C4I0
- STRING:   A2C4I0
- GeneID:   4780718
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_18341
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- ProtClustDB:   PRK05434
- BioCyc:   PMAR167555:NATL1_18341-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 59057; Mature: 58926

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: ACT_SITE 74-74

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSNPAVSINKRKVAPVVLAILDGWGYREEIEHNAVRQASTPVIDALWHAYPHTLIEAS
CCCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHEECC
GADVGLPDEQMGNSEVGHLTIGAGRIIQQELVRISNTVKENKLITNPALNQFSQSLKKGG
CCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHCCC
GTLHIMGLCSDGGVHSHINHLCGLIEWAASKGLKSVSLHLFTDGRDTSAKSANKYINTIE
CEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHH
AKIKSTGVGEISSLCGRYWAMDRDNRWERTSKAYELLTDPRFALSKLSAAESINKSYQEG
HHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
ITDEFIEPVRLSSSFLKDGDGVVFFNFRPDRARQLVKALKLKDFDGFERKNRADIDVLTF
CHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
TQYESGLPVSVAFPPEPLNDLLGQVISDHGLNQYRTAETEKYPHVTYFLNGGIEKPLKGE
EECCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEEECCCCCCCCCCH
VRHLVPSPRVATYDLQPEMSADELTDSCIKAIDSGIYSLVVINFANPDMVGHSGIMTAAI
HHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEE
KANEKVDSCVGKLLNSIGKLGGSLLITADHGNSEMMIGPDGQPWTAHTTNPVPVILIEGE
CCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCEEEEEECCC
KRKLSGYGNDIKLRQSGGGLADLAPTLLHLLNLPKPKAMTGKTLIEPINLPKKPNLIPQP
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCC
AY
CC
>Mature Secondary Structure 
SGSNPAVSINKRKVAPVVLAILDGWGYREEIEHNAVRQASTPVIDALWHAYPHTLIEAS
CCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHEECC
GADVGLPDEQMGNSEVGHLTIGAGRIIQQELVRISNTVKENKLITNPALNQFSQSLKKGG
CCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHCCC
GTLHIMGLCSDGGVHSHINHLCGLIEWAASKGLKSVSLHLFTDGRDTSAKSANKYINTIE
CEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHH
AKIKSTGVGEISSLCGRYWAMDRDNRWERTSKAYELLTDPRFALSKLSAAESINKSYQEG
HHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
ITDEFIEPVRLSSSFLKDGDGVVFFNFRPDRARQLVKALKLKDFDGFERKNRADIDVLTF
CHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
TQYESGLPVSVAFPPEPLNDLLGQVISDHGLNQYRTAETEKYPHVTYFLNGGIEKPLKGE
EECCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEEECCCCCCCCCCH
VRHLVPSPRVATYDLQPEMSADELTDSCIKAIDSGIYSLVVINFANPDMVGHSGIMTAAI
HHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEE
KANEKVDSCVGKLLNSIGKLGGSLLITADHGNSEMMIGPDGQPWTAHTTNPVPVILIEGE
CCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCEEEEEECCC
KRKLSGYGNDIKLRQSGGGLADLAPTLLHLLNLPKPKAMTGKTLIEPINLPKKPNLIPQP
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCC
AY
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA