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The map label for this gene is prmA [H]

Identifier: 124026486

GI number: 124026486

Start: 1460591

End: 1461526

Strand: Reverse

Name: prmA [H]

Synonym: NATL1_17811

Alternate gene names: 124026486

Gene position: 1461526-1460591 (Counterclockwise)

Preceding gene: 124026487

Following gene: 124026485

Centisome position: 78.38

GC content: 34.83

Gene sequence:

>936_bases
TTGTTGGTTGAAAAAACTGTAAATTTGCAAAACTCCCAACTGTCGTGGTTGAGATTGGAGCAGGAATTTTCATTTGAGCT
AGAAGATTCTTTTTATTGGCTTTTAAGCAAACTTGATATTCATAGATTCTCTTTTGAGCATGATCCAGATAACAACTCCA
CTCAAAAGCTATTTATATGGCTTCCTTTGAATGAATGGTCAGTTAGAGATCAAGAGATATTAGTCCAATCATTAATTTCG
TTGACAGAACCTTTTGACTTGACTTTGCCTGAATGCAAATGGATTCAAGTAAAAGATGAAGATTGGAGCTTAAGTTGGAA
AAAAAACTGGAAACCTGATCCCGTAGGAAAATCAATTTTAATTTTGCCAGCATGGTTAGACGTTCCTGAAAAATTTTTAG
AACGTAAAATTATTCGTCTAGATCCAGGTAGTGCTTTTGGCACTGGTAGTCATCCTTCCACTAGGCTATGCCTTGAAGCC
TTGGATAATGAACCTCCGGTAGGTCAAACAATTGCTGATATAGGTTGTGGAAGCGGAATACTGTCTTTAACTGCATTGAA
ATTAGGAGCCAAGAGTACGTTCTCTGTTGATACTGATTCTCTTTCAATATCAGCTACTAAAATTAATTCTGCCTTAAATG
ATTGTTCTGAAAACCTCTTAAATGTTTTTCTTGGTTCTATTGAGGAAATTGAGGCGAATATGCCGAAAGAAAAAATTGAT
TTGATCCTATGCAATATTCTTGCACCTGTCATAAAATTATTAGGGCCAAGTTTCGAAAAAATCATTGGACATAAAGGTAA
AGTGATTTTATCGGGTTTGTTAGTTCAGCAAATCAAAGAACTTCAAGAATTTTTTTTAAAGCTTGGTTGGCAAGTTCTTG
AAATAAAGAAAAAGGATCAATGGGCCTTAATGGTTTTGACTCTTAATTTGTCTTGA

Upstream 100 bases:

>100_bases
GTAATGGTTTTAAGTATCGATGACCCCATCCCTTCTGAGTTGTTGGGCTCAATTCTTTCAATGCAAGGAATTAACGAAGC
TCATTCAGTGACTCTGTAAT

Downstream 100 bases:

>100_bases
TTAAATAAATTCTAAATTTTCAGATTTTAAAAAACCTCATGACATCTTTTAAGATCACTTTTATTAATGAATTAAGTGGT
TTAAAAGAAATTATTGATAT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MLVEKTVNLQNSQLSWLRLEQEFSFELEDSFYWLLSKLDIHRFSFEHDPDNNSTQKLFIWLPLNEWSVRDQEILVQSLIS
LTEPFDLTLPECKWIQVKDEDWSLSWKKNWKPDPVGKSILILPAWLDVPEKFLERKIIRLDPGSAFGTGSHPSTRLCLEA
LDNEPPVGQTIADIGCGSGILSLTALKLGAKSTFSVDTDSLSISATKINSALNDCSENLLNVFLGSIEEIEANMPKEKID
LILCNILAPVIKLLGPSFEKIIGHKGKVILSGLLVQQIKELQEFFLKLGWQVLEIKKKDQWALMVLTLNLS

Sequences:

>Translated_311_residues
MLVEKTVNLQNSQLSWLRLEQEFSFELEDSFYWLLSKLDIHRFSFEHDPDNNSTQKLFIWLPLNEWSVRDQEILVQSLIS
LTEPFDLTLPECKWIQVKDEDWSLSWKKNWKPDPVGKSILILPAWLDVPEKFLERKIIRLDPGSAFGTGSHPSTRLCLEA
LDNEPPVGQTIADIGCGSGILSLTALKLGAKSTFSVDTDSLSISATKINSALNDCSENLLNVFLGSIEEIEANMPKEKID
LILCNILAPVIKLLGPSFEKIIGHKGKVILSGLLVQQIKELQEFFLKLGWQVLEIKKKDQWALMVLTLNLS
>Mature_311_residues
MLVEKTVNLQNSQLSWLRLEQEFSFELEDSFYWLLSKLDIHRFSFEHDPDNNSTQKLFIWLPLNEWSVRDQEILVQSLIS
LTEPFDLTLPECKWIQVKDEDWSLSWKKNWKPDPVGKSILILPAWLDVPEKFLERKIIRLDPGSAFGTGSHPSTRLCLEA
LDNEPPVGQTIADIGCGSGILSLTALKLGAKSTFSVDTDSLSISATKINSALNDCSENLLNVFLGSIEEIEANMPKEKID
LILCNILAPVIKLLGPSFEKIIGHKGKVILSGLLVQQIKELQEFFLKLGWQVLEIKKKDQWALMVLTLNLS

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=162, Percent_Identity=40.7407407407407, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 35243; Mature: 35243

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVEKTVNLQNSQLSWLRLEQEFSFELEDSFYWLLSKLDIHRFSFEHDPDNNSTQKLFIW
CCCCCCCCCCCCCCCEEEEHHHCCEEECCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEE
LPLNEWSVRDQEILVQSLISLTEPFDLTLPECKWIQVKDEDWSLSWKKNWKPDPVGKSIL
EECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCEEE
ILPAWLDVPEKFLERKIIRLDPGSAFGTGSHPSTRLCLEALDNEPPVGQTIADIGCGSGI
EEECHHCCHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCH
LSLTALKLGAKSTFSVDTDSLSISATKINSALNDCSENLLNVFLGSIEEIEANMPKEKID
HHHHHHHHCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHH
LILCNILAPVIKLLGPSFEKIIGHKGKVILSGLLVQQIKELQEFFLKLGWQVLEIKKKDQ
HHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
WALMVLTLNLS
EEEEEEEEECC
>Mature Secondary Structure
MLVEKTVNLQNSQLSWLRLEQEFSFELEDSFYWLLSKLDIHRFSFEHDPDNNSTQKLFIW
CCCCCCCCCCCCCCCEEEEHHHCCEEECCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEE
LPLNEWSVRDQEILVQSLISLTEPFDLTLPECKWIQVKDEDWSLSWKKNWKPDPVGKSIL
EECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCEEE
ILPAWLDVPEKFLERKIIRLDPGSAFGTGSHPSTRLCLEALDNEPPVGQTIADIGCGSGI
EEECHHCCHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCH
LSLTALKLGAKSTFSVDTDSLSISATKINSALNDCSENLLNVFLGSIEEIEANMPKEKID
HHHHHHHHCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHH
LILCNILAPVIKLLGPSFEKIIGHKGKVILSGLLVQQIKELQEFFLKLGWQVLEIKKKDQ
HHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
WALMVLTLNLS
EEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]