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The map label for this gene is surE

Identifier: 124026395

GI number: 124026395

Start: 1378048

End: 1378836

Strand: Direct

Name: surE

Synonym: NATL1_16901

Alternate gene names: 124026395

Gene position: 1378048-1378836 (Clockwise)

Preceding gene: 124026392

Following gene: 124026397

Centisome position: 73.9

GC content: 40.05

Gene sequence:

>789_bases
ATGAAACCATTGAAAATTTTAATTAGTAATGATGATGGTGTTTTTGCAGAAGGAATAAGAACACTTGCCACATCTGCAGC
GAGCAGAGGACATAAAGTTACTGTTGTTTGTCCAGATCAAGAAAGATCCGCAACTGGTCATGGATTAACTTTACATTCGC
CCATACGCGCTGAAAAGGCAGACGAATTATTTGGGGGAGGTATTAAAGCTTGGGGATGTACTGGAACCCCTGCTGATTGC
GTAAAACTCGCACTTAATGAACTTCTTGATCAAAAGCCAGACTTAATTCTTTCTGGAATTAATCATGGGCCTAATCTTGG
TACGGATATTTTTTGCTCAGGGACTGTTGCTGCTGCTCTTGAGGGGACCTTAGATGGGATTCCATCTATTGCGGTGAGCG
TTGCAAGTTTTCAATGGAAAAATTTTAGTTTCGCTGGGAAACTTTCCTTAGATATTGCAGAGAAAGCAATTCAACAAAAT
TGGCCCAAGAACTTACTCCTAAATTTAAATATTCCCCCTTGTGAAGAAAAAGAAATGGGTGATTTGGTTTGGACAAGACT
TTCAATCAGACAATACGAAGAACAATTCATTCGAAGAGTCGATCCAAGAGGTAATACCTATTTTTGGATGGCTGGGGAAG
CAGTAACAGATCTTCAATCTGCTGGAGAAGGGCCTAAGGGATGGCCAAGTGATGTCTCTCAAATCGCTATATGCTCTCCC
TCATTAACGCCAATTCAACCTGATCTTTTTTGGAGAGGAAATTTAGATGATTTGCCAAACTTAATATAA

Upstream 100 bases:

>100_bases
ATGAGCTGTTTTAGGGATAATGTTGAACTCAATGAATTGCCATCTCGAGTACTAGTTTAATCGGCAACCTGTCCCAGTTC
TAAAAACTATTAGCAAAAAA

Downstream 100 bases:

>100_bases
AAATTAGTTTTTCCTGAAAATCCTTTGCAATAACCATAAAGAAAAAATCAGCCCAATCAGATGGGCAAACAAAACCTGGG
TATTACTCAAGACAGAAAGC

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MKPLKILISNDDGVFAEGIRTLATSAASRGHKVTVVCPDQERSATGHGLTLHSPIRAEKADELFGGGIKAWGCTGTPADC
VKLALNELLDQKPDLILSGINHGPNLGTDIFCSGTVAAALEGTLDGIPSIAVSVASFQWKNFSFAGKLSLDIAEKAIQQN
WPKNLLLNLNIPPCEEKEMGDLVWTRLSIRQYEEQFIRRVDPRGNTYFWMAGEAVTDLQSAGEGPKGWPSDVSQIAICSP
SLTPIQPDLFWRGNLDDLPNLI

Sequences:

>Translated_262_residues
MKPLKILISNDDGVFAEGIRTLATSAASRGHKVTVVCPDQERSATGHGLTLHSPIRAEKADELFGGGIKAWGCTGTPADC
VKLALNELLDQKPDLILSGINHGPNLGTDIFCSGTVAAALEGTLDGIPSIAVSVASFQWKNFSFAGKLSLDIAEKAIQQN
WPKNLLLNLNIPPCEEKEMGDLVWTRLSIRQYEEQFIRRVDPRGNTYFWMAGEAVTDLQSAGEGPKGWPSDVSQIAICSP
SLTPIQPDLFWRGNLDDLPNLI
>Mature_262_residues
MKPLKILISNDDGVFAEGIRTLATSAASRGHKVTVVCPDQERSATGHGLTLHSPIRAEKADELFGGGIKAWGCTGTPADC
VKLALNELLDQKPDLILSGINHGPNLGTDIFCSGTVAAALEGTLDGIPSIAVSVASFQWKNFSFAGKLSLDIAEKAIQQN
WPKNLLLNLNIPPCEEKEMGDLVWTRLSIRQYEEQFIRRVDPRGNTYFWMAGEAVTDLQSAGEGPKGWPSDVSQIAICSP
SLTPIQPDLFWRGNLDDLPNLI

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=246, Percent_Identity=36.9918699186992, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_PROM1 (A2C436)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015510.1
- ProteinModelPortal:   A2C436
- SMR:   A2C436
- STRING:   A2C436
- GeneID:   4779498
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_16901
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- ProtClustDB:   PRK00346
- BioCyc:   PMAR167555:NATL1_16901-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 28365; Mature: 28365

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLKILISNDDGVFAEGIRTLATSAASRGHKVTVVCPDQERSATGHGLTLHSPIRAEKA
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCCCCHHHH
DELFGGGIKAWGCTGTPADCVKLALNELLDQKPDLILSGINHGPNLGTDIFCSGTVAAAL
HHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEECCHHHHHH
EGTLDGIPSIAVSVASFQWKNFSFAGKLSLDIAEKAIQQNWPKNLLLNLNIPPCEEKEMG
HHHHCCCCHHHHHHHHEEECCCCEECEEEHHHHHHHHHCCCCCCEEEECCCCCCCCCHHH
DLVWTRLSIRQYEEQFIRRVDPRGNTYFWMAGEAVTDLQSAGEGPKGWPSDVSQIAICSP
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCEEEEECC
SLTPIQPDLFWRGNLDDLPNLI
CCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MKPLKILISNDDGVFAEGIRTLATSAASRGHKVTVVCPDQERSATGHGLTLHSPIRAEKA
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCCCCHHHH
DELFGGGIKAWGCTGTPADCVKLALNELLDQKPDLILSGINHGPNLGTDIFCSGTVAAAL
HHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEECCHHHHHH
EGTLDGIPSIAVSVASFQWKNFSFAGKLSLDIAEKAIQQNWPKNLLLNLNIPPCEEKEMG
HHHHCCCCHHHHHHHHEEECCCCEECEEEHHHHHHHHHCCCCCCEEEECCCCCCCCCHHH
DLVWTRLSIRQYEEQFIRRVDPRGNTYFWMAGEAVTDLQSAGEGPKGWPSDVSQIAICSP
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCEEEEECC
SLTPIQPDLFWRGNLDDLPNLI
CCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA