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The map label for this gene is cobL [H]

Identifier: 124026392

GI number: 124026392

Start: 1374680

End: 1375966

Strand: Direct

Name: cobL [H]

Synonym: NATL1_16871

Alternate gene names: 124026392

Gene position: 1374680-1375966 (Clockwise)

Preceding gene: 124026387

Following gene: 124026395

Centisome position: 73.72

GC content: 32.01

Gene sequence:

>1287_bases
ATGCCTGATGAGTCAAAGCAGATACACGTAATAGGAATTGATACTTCAAGTGTTGAAAGTTTTTTTGAAGCTAAAAAAAA
ACCAATTTTTGAAGCTGAGATAATCACTGGTCCACAAAGAATTTTAGATTCTTTCAAAACTTGGTTAAAGGATAAAAATA
TAAAAAATCATAAGTTCGAGTTCATTGCTACTGACAAACTAAACGACTTTATAGATCTATTAAAAAAGGGCAAGAAAAAA
ACAATTGTATTTTCTGGTGGTGATCCTCTTTGGTTTGGGATTGGTAGATTATTAATTCAAAACTTTCCTTTATCAAAACT
TTATTTTGAGCCAGCCGCGACCTCTTTCCAACTCGCTTTTTCAAGACTTGGCAAACCTTGGCAAAATACAAAATGGATCA
GTCTTCATGGAAGAGACCCGCTTCAATTTGAAAAAGCAATTAAAAAGCTTCCTTCTTCACTTGTGGTTTTAACTGACTCA
AATAGAGGAGGAGCTAAGGAGGTTTATCAATTAATGGATTCCTTGGAACTTCAGAAAAAATATGAATTTTGGACTTTCGA
AAGGCTTGGATATATCAATGAAAGAATTCTAAAAATATCTTCTGTTGATGATTTCCCAATTGATCTTGATCCATTGCATC
TTGTGATTCTTTTAAAAAAAGAAGAGCCTCTAATACAATCAAAAGATTTACCTTTATTTGGAATTGTTGATTCAGTTTTT
CTTCAAAATGCAGACTGCCCTGGGTTAATGACAAAAAAAGAAGTTAGGGTTCAAATTCTTGCCGAACTTAATCTCCCAAA
GCGAGGAATAATTTGGGACATAGGAAGTGGAGTTGGGAGTATTGGTTTAGAAGCATTAAGGATATCTCCAAATCTAAAAT
TAGTATCCATTGATAAAAGAGTTGGAAGTACAAATATAATCAAGGAAAACGCCAGAAGGCTTGGCGTTAAGCCATCATTG
ATAATTGAGGATGAAGCATTAAATATATTTAAACAAAATAAAATAACATCAAGTCTTTCAAAACCAGAAAGAGTTATTAT
CGGAGGCGGGGGCTCAAACTCACATTTAATTCTTGAAGAAGTTTTGAAGCTTATAAATAGTACTTGTATAATTGTTATCC
CACTAATATCATTAAAATCTATATCAAAATTAGAGTCGATTTTAAAGCCTAAAGCACACAAGTTATCTATTAGTCAACAT
CAATCGTATAGAGGTGTAAGTATTGGAGAAGATATAAGATTATCTCCTTTAAATCCTGTTTTTATTTTGAAAGGTGAAAT
TAAATAA

Upstream 100 bases:

>100_bases
ACAAAACTTTCAAACTAACTAATGAAGTTTTAGTTGATTTTCATCAAAAAAATAGTAAAGCTATAAAAAAGAAATTTTTC
TACGCCCACTCATTTAAACC

Downstream 100 bases:

>100_bases
TTTTTATGTTTTATCAGGTTTCGCAACGTGGGGGAGTCCCCAACCTAATTTATTTCTTAGAACTTGAAAGAACTCATGAT
CGGAAAGTCTAATGAACTTA

Product: putative precorrin-6y methylase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MPDESKQIHVIGIDTSSVESFFEAKKKPIFEAEIITGPQRILDSFKTWLKDKNIKNHKFEFIATDKLNDFIDLLKKGKKK
TIVFSGGDPLWFGIGRLLIQNFPLSKLYFEPAATSFQLAFSRLGKPWQNTKWISLHGRDPLQFEKAIKKLPSSLVVLTDS
NRGGAKEVYQLMDSLELQKKYEFWTFERLGYINERILKISSVDDFPIDLDPLHLVILLKKEEPLIQSKDLPLFGIVDSVF
LQNADCPGLMTKKEVRVQILAELNLPKRGIIWDIGSGVGSIGLEALRISPNLKLVSIDKRVGSTNIIKENARRLGVKPSL
IIEDEALNIFKQNKITSSLSKPERVIIGGGGSNSHLILEEVLKLINSTCIIVIPLISLKSISKLESILKPKAHKLSISQH
QSYRGVSIGEDIRLSPLNPVFILKGEIK

Sequences:

>Translated_428_residues
MPDESKQIHVIGIDTSSVESFFEAKKKPIFEAEIITGPQRILDSFKTWLKDKNIKNHKFEFIATDKLNDFIDLLKKGKKK
TIVFSGGDPLWFGIGRLLIQNFPLSKLYFEPAATSFQLAFSRLGKPWQNTKWISLHGRDPLQFEKAIKKLPSSLVVLTDS
NRGGAKEVYQLMDSLELQKKYEFWTFERLGYINERILKISSVDDFPIDLDPLHLVILLKKEEPLIQSKDLPLFGIVDSVF
LQNADCPGLMTKKEVRVQILAELNLPKRGIIWDIGSGVGSIGLEALRISPNLKLVSIDKRVGSTNIIKENARRLGVKPSL
IIEDEALNIFKQNKITSSLSKPERVIIGGGGSNSHLILEEVLKLINSTCIIVIPLISLKSISKLESILKPKAHKLSISQH
QSYRGVSIGEDIRLSPLNPVFILKGEIK
>Mature_427_residues
PDESKQIHVIGIDTSSVESFFEAKKKPIFEAEIITGPQRILDSFKTWLKDKNIKNHKFEFIATDKLNDFIDLLKKGKKKT
IVFSGGDPLWFGIGRLLIQNFPLSKLYFEPAATSFQLAFSRLGKPWQNTKWISLHGRDPLQFEKAIKKLPSSLVVLTDSN
RGGAKEVYQLMDSLELQKKYEFWTFERLGYINERILKISSVDDFPIDLDPLHLVILLKKEEPLIQSKDLPLFGIVDSVFL
QNADCPGLMTKKEVRVQILAELNLPKRGIIWDIGSGVGSIGLEALRISPNLKLVSIDKRVGSTNIIKENARRLGVKPSLI
IEDEALNIFKQNKITSSLSKPERVIIGGGGSNSHLILEEVLKLINSTCIIVIPLISLKSISKLESILKPKAHKLSISQHQ
SYRGVSIGEDIRLSPLNPVFILKGEIK

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 48152; Mature: 48021

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDESKQIHVIGIDTSSVESFFEAKKKPIFEAEIITGPQRILDSFKTWLKDKNIKNHKFE
CCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEE
FIATDKLNDFIDLLKKGKKKTIVFSGGDPLWFGIGRLLIQNFPLSKLYFEPAATSFQLAF
EEECCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHEEECCCCCHHHHHH
SRLGKPWQNTKWISLHGRDPLQFEKAIKKLPSSLVVLTDSNRGGAKEVYQLMDSLELQKK
HHCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHH
YEFWTFERLGYINERILKISSVDDFPIDLDPLHLVILLKKEEPLIQSKDLPLFGIVDSVF
HCCHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHH
LQNADCPGLMTKKEVRVQILAELNLPKRGIIWDIGSGVGSIGLEALRISPNLKLVSIDKR
HCCCCCCCCCCHHHHEEEEEEECCCCCCCEEEECCCCCCCCCEEEEEECCCEEEEEECCC
VGSTNIIKENARRLGVKPSLIIEDEALNIFKQNKITSSLSKPERVIIGGGGSNSHLILEE
CCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
VLKLINSTCIIVIPLISLKSISKLESILKPKAHKLSISQHQSYRGVSIGEDIRLSPLNPV
HHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCEECCCCEE
FILKGEIK
EEEEECCC
>Mature Secondary Structure 
PDESKQIHVIGIDTSSVESFFEAKKKPIFEAEIITGPQRILDSFKTWLKDKNIKNHKFE
CCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEE
FIATDKLNDFIDLLKKGKKKTIVFSGGDPLWFGIGRLLIQNFPLSKLYFEPAATSFQLAF
EEECCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHEEECCCCCHHHHHH
SRLGKPWQNTKWISLHGRDPLQFEKAIKKLPSSLVVLTDSNRGGAKEVYQLMDSLELQKK
HHCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHH
YEFWTFERLGYINERILKISSVDDFPIDLDPLHLVILLKKEEPLIQSKDLPLFGIVDSVF
HCCHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHH
LQNADCPGLMTKKEVRVQILAELNLPKRGIIWDIGSGVGSIGLEALRISPNLKLVSIDKR
HCCCCCCCCCCHHHHEEEEEEECCCCCCCEEEECCCCCCCCCEEEEEECCCEEEEEECCC
VGSTNIIKENARRLGVKPSLIIEDEALNIFKQNKITSSLSKPERVIIGGGGSNSHLILEE
CCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
VLKLINSTCIIVIPLISLKSISKLESILKPKAHKLSISQHQSYRGVSIGEDIRLSPLNPV
HHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCEECCCCEE
FILKGEIK
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]