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The map label for this gene is lasT [C]

Identifier: 124026236

GI number: 124026236

Start: 1244915

End: 1245652

Strand: Direct

Name: lasT [C]

Synonym: NATL1_15301

Alternate gene names: 124026236

Gene position: 1244915-1245652 (Clockwise)

Preceding gene: 124026235

Following gene: 124026237

Centisome position: 66.76

GC content: 33.6

Gene sequence:

>738_bases
GTGGCTATAAATAAAACTCTAAAAGTAATACTTGTCGAGCCAGCGGGGCCAATCAATGTTGGGAGTGTTGCAAGACTCTG
TGAAAACTTTAGTGTTCATGAATTACGACTAGTTTCACCTAAATGCGAATATTTAGCTCAAGAAGCAAAAAAGATGGCTG
TAAGAGGATTGAAGATCTTAGAGAAAGCAAAAGTGTATGAAGATCTAAATTCAGCACTTTCAGACTGCTCAAGAATTATT
GCCACTTGCGGTAGAAAAGAACATGGAGAAATCCCTCTTAATTCAAATAAAGATGCTTTGAGCTGGGTTCTTAAATCAGA
AAGAGAAGAGACAATAGCTTTAGTTTTTGGAAGAGAGGACAGAGGTTTATCTAACGAGGAGCTTTTAAAAGCAAATAAAG
TGATTAGTCTTAATACCAGCGAGGATTATCCATCATTAAATCTTTCACATGCAGTAGCAATTGTTCTTCATCAATTCAAC
CAATTGAATGATCTTGATTTATTAAAAAAACATACTAAAACAAGCTCTCCTGCGAATTTAATTAAATTAGAAGATTGTAT
TAATGACGCAGGTAGTCTTTTGCTTGATATTGGTTTCTTGATGAAACATACCTACAAAGCTAAAATGACGAAGATCAAAC
AATTACTTTTGAGAGGTGAGATAAAAGATGATGAAGTTGCACTAATTAGAGGTATAATTAGCCAAGCAAGATGGAAGATT
AAAAATAAAAATGATTAA

Upstream 100 bases:

>100_bases
ATCAAGTTATTCGAGGATTGACTCCACCAATGCCAAGTTTTGAAATCGAACCTCAATCAATGGCTGATCTGCTGGAGTAT
ATGCATTCACTCAATTAAAA

Downstream 100 bases:

>100_bases
TCAAAATAACAAGCTACAATAAATAGCAAAGATATATATTCTTTAATTTCAAAGTGAAAAGACACCTAAAAGTAATAGCA
AATATATTTCTAACAAGCAT

Product: tRNA/rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MAINKTLKVILVEPAGPINVGSVARLCENFSVHELRLVSPKCEYLAQEAKKMAVRGLKILEKAKVYEDLNSALSDCSRII
ATCGRKEHGEIPLNSNKDALSWVLKSEREETIALVFGREDRGLSNEELLKANKVISLNTSEDYPSLNLSHAVAIVLHQFN
QLNDLDLLKKHTKTSSPANLIKLEDCINDAGSLLLDIGFLMKHTYKAKMTKIKQLLLRGEIKDDEVALIRGIISQARWKI
KNKND

Sequences:

>Translated_245_residues
MAINKTLKVILVEPAGPINVGSVARLCENFSVHELRLVSPKCEYLAQEAKKMAVRGLKILEKAKVYEDLNSALSDCSRII
ATCGRKEHGEIPLNSNKDALSWVLKSEREETIALVFGREDRGLSNEELLKANKVISLNTSEDYPSLNLSHAVAIVLHQFN
QLNDLDLLKKHTKTSSPANLIKLEDCINDAGSLLLDIGFLMKHTYKAKMTKIKQLLLRGEIKDDEVALIRGIISQARWKI
KNKND
>Mature_244_residues
AINKTLKVILVEPAGPINVGSVARLCENFSVHELRLVSPKCEYLAQEAKKMAVRGLKILEKAKVYEDLNSALSDCSRIIA
TCGRKEHGEIPLNSNKDALSWVLKSEREETIALVFGREDRGLSNEELLKANKVISLNTSEDYPSLNLSHAVAIVLHQFNQ
LNDLDLLKKHTKTSSPANLIKLEDCINDAGSLLLDIGFLMKHTYKAKMTKIKQLLLRGEIKDDEVALIRGIISQARWKIK
NKND

Specific function: Unknown

COG id: COG0565

COG function: function code J; rRNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Escherichia coli, GI1788881, Length=236, Percent_Identity=27.5423728813559, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790865, Length=197, Percent_Identity=31.4720812182741, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004384
- InterPro:   IPR001537 [H]

Pfam domain/function: PF00588 SpoU_methylase [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27397; Mature: 27266

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINKTLKVILVEPAGPINVGSVARLCENFSVHELRLVSPKCEYLAQEAKKMAVRGLKIL
CCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
EKAKVYEDLNSALSDCSRIIATCGRKEHGEIPLNSNKDALSWVLKSEREETIALVFGRED
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCC
RGLSNEELLKANKVISLNTSEDYPSLNLSHAVAIVLHQFNQLNDLDLLKKHTKTSSPANL
CCCCHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHH
IKLEDCINDAGSLLLDIGFLMKHTYKAKMTKIKQLLLRGEIKDDEVALIRGIISQARWKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
KNKND
CCCCC
>Mature Secondary Structure 
AINKTLKVILVEPAGPINVGSVARLCENFSVHELRLVSPKCEYLAQEAKKMAVRGLKIL
CCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
EKAKVYEDLNSALSDCSRIIATCGRKEHGEIPLNSNKDALSWVLKSEREETIALVFGRED
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCC
RGLSNEELLKANKVISLNTSEDYPSLNLSHAVAIVLHQFNQLNDLDLLKKHTKTSSPANL
CCCCHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHH
IKLEDCINDAGSLLLDIGFLMKHTYKAKMTKIKQLLLRGEIKDDEVALIRGIISQARWKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
KNKND
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]