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The map label for this gene is recD [H]

Identifier: 124026184

GI number: 124026184

Start: 1187910

End: 1189631

Strand: Direct

Name: recD [H]

Synonym: NATL1_14781

Alternate gene names: 124026184

Gene position: 1187910-1189631 (Clockwise)

Preceding gene: 124026183

Following gene: 124026185

Centisome position: 63.7

GC content: 34.26

Gene sequence:

>1722_bases
ATGAGATATTCCTTGGAAAAACTTTTTTCAACTGATTTAAATAAATCATTATTGGCTACTCTAATTCGCTATTACCCACC
GATAGATTCTAATGAAGCTTTAATAGATATTGTAAATGTATTAATGGATGGATTATCAAGAGGCGATGTTTACATAGACA
TGAAGAAAATCCCTGAAAATCTTGAACTTAAATATAAAAATTGGCCCAGCTATCATATGAAAGCATTACTAGATAGTGGC
TGGACTAAAGGAGATAACTCCCCAATAGTTTTAGATGGAGATTTGATTAGTTGGCGTCGTACACATAATGAGATAGTTGA
GACCATTCAAAAAATACTATTAAGGAATCAACCTATTAATAACCTTTCTAAAGAATTACCTGTTCGAATTGATGATAAGA
ATCTAGCGCATCTAAATATTCAACAAAAAGAAGCTGTTAACCTTGTTAAAAGTGAACAAATCATATTATTAAGTGGTGGC
CCAGGCACAGGCAAAACAAGTACCATTCTTCAAATGCTTTTACAAGCACTAACAAGAAATCCGACTCTTGATATTGCAAT
GGCTGCTCCAACAGGGAAAGCCGCAAAAAAACTAAAAGATACTATTCAGGCGGGTATTGAAGATTTTGATGATCCTGTAA
AGGATAAGCTTTCTAACATTCCTTCGAAAACATTACATAAATGGTTAGAAGCAAGTCCAAATGGCTTCAGAAGGAACTCT
CAACGTCTATTAAAATTAGACCTCATCGTCATAGATGAGATGTCAATGGTTGACTTGCCAACCATAAATGGATTACTCGA
TGCATTAACAAAATCATGTCAAATAATCTTAGTAGGTGATCCTGACCAATTATTGCCAATAGGAAGTGGTGGTATATGGC
AAATTTTGCAAGAGAAAAAAACGAAAACACACTTTCATGCAAACTCAGTCAAGCTAACAAAGTCATACCGAAACAAAGGT
GATATCGCGTTATTAAGAAATACATTAAAAGATAAAGGAGTAGATGCGTTTTGGCACCTGCTTTCAACAAAAGAAGATTC
AACAAATACACTTAAGTACCTTTCATCCCTAAAAAGTGTTCCAGATCCAGTGGCTAGAACTCTTGTCAGCTATAGAAAGA
AGCTTAAAAAGTTAACAGAAAATTGTATTAATTATATTCCAGATGAAGCATGGCAATCGAGCATGGTTGAGGTAGAACAA
TCAGTTGAGATACTAAAACTCTTTAAATTTATAGATAATCTTCTTATACTTTGTCCGCAAAGGTATGGACCCTGGGGTGT
AAATAAAATCCACGAGTTTCTTTTAGGAAAGAGATTTGAGAAGGAAGTACACAAGTGGGTAGAGGGAACACCAATCATGG
CAAAAAGTAATCAACCTGAAATAGGTTTAGCGAATGGAGACGTTGGGATAATTATTGGCAACGGCGAAAAAAGACGTTTT
TTATTTAATGTTTTTTCTGAGGAACAAAGACTAGTAACTCGATTAATAAACCCATCAAGGTTAAATAGATATGATGCGGC
ATATGCAATGACAATTCATAAAGCACAGGGGAGTGAAGCTGATCAAGTTCTTTTACTTTGGCCAACAACCTCAAAAGTTC
CAGAAGAGAAGACTTTCAATAAATTTTATTCTGATGATTATGAAAAAAGAATGCTTTACACAGCAATAACTCGTGCAAAA
AAACAATTACTGGTAATTACCAATAAAGAAGAAGACTTTTAA

Upstream 100 bases:

>100_bases
AAGAAAAGAATTTTCCTCAAAGGACTCCAGGCTTAATTGTCGAACCTGCTCCTATTGAAAGAATAAAAAAATTAGATTTG
TTGATTAAAAGACAACAGAA

Downstream 100 bases:

>100_bases
ATATGTACTCAACTTTTTCCTAAAAGGATTTTTGAAATGATAAAGTGAGATTATATCCCTTTAACAAGGCGAGTCAGCAA
AGCACGGTTATACACCGATC

Product: exodeoxyribonuclease V 67 kD polypeptide

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MRYSLEKLFSTDLNKSLLATLIRYYPPIDSNEALIDIVNVLMDGLSRGDVYIDMKKIPENLELKYKNWPSYHMKALLDSG
WTKGDNSPIVLDGDLISWRRTHNEIVETIQKILLRNQPINNLSKELPVRIDDKNLAHLNIQQKEAVNLVKSEQIILLSGG
PGTGKTSTILQMLLQALTRNPTLDIAMAAPTGKAAKKLKDTIQAGIEDFDDPVKDKLSNIPSKTLHKWLEASPNGFRRNS
QRLLKLDLIVIDEMSMVDLPTINGLLDALTKSCQIILVGDPDQLLPIGSGGIWQILQEKKTKTHFHANSVKLTKSYRNKG
DIALLRNTLKDKGVDAFWHLLSTKEDSTNTLKYLSSLKSVPDPVARTLVSYRKKLKKLTENCINYIPDEAWQSSMVEVEQ
SVEILKLFKFIDNLLILCPQRYGPWGVNKIHEFLLGKRFEKEVHKWVEGTPIMAKSNQPEIGLANGDVGIIIGNGEKRRF
LFNVFSEEQRLVTRLINPSRLNRYDAAYAMTIHKAQGSEADQVLLLWPTTSKVPEEKTFNKFYSDDYEKRMLYTAITRAK
KQLLVITNKEEDF

Sequences:

>Translated_573_residues
MRYSLEKLFSTDLNKSLLATLIRYYPPIDSNEALIDIVNVLMDGLSRGDVYIDMKKIPENLELKYKNWPSYHMKALLDSG
WTKGDNSPIVLDGDLISWRRTHNEIVETIQKILLRNQPINNLSKELPVRIDDKNLAHLNIQQKEAVNLVKSEQIILLSGG
PGTGKTSTILQMLLQALTRNPTLDIAMAAPTGKAAKKLKDTIQAGIEDFDDPVKDKLSNIPSKTLHKWLEASPNGFRRNS
QRLLKLDLIVIDEMSMVDLPTINGLLDALTKSCQIILVGDPDQLLPIGSGGIWQILQEKKTKTHFHANSVKLTKSYRNKG
DIALLRNTLKDKGVDAFWHLLSTKEDSTNTLKYLSSLKSVPDPVARTLVSYRKKLKKLTENCINYIPDEAWQSSMVEVEQ
SVEILKLFKFIDNLLILCPQRYGPWGVNKIHEFLLGKRFEKEVHKWVEGTPIMAKSNQPEIGLANGDVGIIIGNGEKRRF
LFNVFSEEQRLVTRLINPSRLNRYDAAYAMTIHKAQGSEADQVLLLWPTTSKVPEEKTFNKFYSDDYEKRMLYTAITRAK
KQLLVITNKEEDF
>Mature_573_residues
MRYSLEKLFSTDLNKSLLATLIRYYPPIDSNEALIDIVNVLMDGLSRGDVYIDMKKIPENLELKYKNWPSYHMKALLDSG
WTKGDNSPIVLDGDLISWRRTHNEIVETIQKILLRNQPINNLSKELPVRIDDKNLAHLNIQQKEAVNLVKSEQIILLSGG
PGTGKTSTILQMLLQALTRNPTLDIAMAAPTGKAAKKLKDTIQAGIEDFDDPVKDKLSNIPSKTLHKWLEASPNGFRRNS
QRLLKLDLIVIDEMSMVDLPTINGLLDALTKSCQIILVGDPDQLLPIGSGGIWQILQEKKTKTHFHANSVKLTKSYRNKG
DIALLRNTLKDKGVDAFWHLLSTKEDSTNTLKYLSSLKSVPDPVARTLVSYRKKLKKLTENCINYIPDEAWQSSMVEVEQ
SVEILKLFKFIDNLLILCPQRYGPWGVNKIHEFLLGKRFEKEVHKWVEGTPIMAKSNQPEIGLANGDVGIIIGNGEKRRF
LFNVFSEEQRLVTRLINPSRLNRYDAAYAMTIHKAQGSEADQVLLLWPTTSKVPEEKTFNKFYSDDYEKRMLYTAITRAK
KQLLVITNKEEDF

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=430, Percent_Identity=27.6744186046512, Blast_Score=143, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 65180; Mature: 65180

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYSLEKLFSTDLNKSLLATLIRYYPPIDSNEALIDIVNVLMDGLSRGDVYIDMKKIPEN
CCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHCCCC
LELKYKNWPSYHMKALLDSGWTKGDNSPIVLDGDLISWRRTHNEIVETIQKILLRNQPIN
CEEEECCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHH
NLSKELPVRIDDKNLAHLNIQQKEAVNLVKSEQIILLSGGPGTGKTSTILQMLLQALTRN
HHHHHCCEEECCCCCEEEECCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCC
PTLDIAMAAPTGKAAKKLKDTIQAGIEDFDDPVKDKLSNIPSKTLHKWLEASPNGFRRNS
CCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
QRLLKLDLIVIDEMSMVDLPTINGLLDALTKSCQIILVGDPDQLLPIGSGGIWQILQEKK
CCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEECCCCHHHHHHHHHH
TKTHFHANSVKLTKSYRNKGDIALLRNTLKDKGVDAFWHLLSTKEDSTNTLKYLSSLKSV
HHHEEECCCEEEEHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCC
PDPVARTLVSYRKKLKKLTENCINYIPDEAWQSSMVEVEQSVEILKLFKFIDNLLILCPQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
RYGPWGVNKIHEFLLGKRFEKEVHKWVEGTPIMAKSNQPEIGLANGDVGIIIGNGEKRRF
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCEEEEEECCCCCCH
LFNVFSEEQRLVTRLINPSRLNRYDAAYAMTIHKAQGSEADQVLLLWPTTSKVPEEKTFN
HHHHHHHHHHHHHHHCCHHHCCHHHHHEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHH
KFYSDDYEKRMLYTAITRAKKQLLVITNKEEDF
HHHCCCHHHHHHHHHHHHHCCEEEEEECCCCCC
>Mature Secondary Structure
MRYSLEKLFSTDLNKSLLATLIRYYPPIDSNEALIDIVNVLMDGLSRGDVYIDMKKIPEN
CCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHCCCC
LELKYKNWPSYHMKALLDSGWTKGDNSPIVLDGDLISWRRTHNEIVETIQKILLRNQPIN
CEEEECCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHH
NLSKELPVRIDDKNLAHLNIQQKEAVNLVKSEQIILLSGGPGTGKTSTILQMLLQALTRN
HHHHHCCEEECCCCCEEEECCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCC
PTLDIAMAAPTGKAAKKLKDTIQAGIEDFDDPVKDKLSNIPSKTLHKWLEASPNGFRRNS
CCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
QRLLKLDLIVIDEMSMVDLPTINGLLDALTKSCQIILVGDPDQLLPIGSGGIWQILQEKK
CCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEECCCCHHHHHHHHHH
TKTHFHANSVKLTKSYRNKGDIALLRNTLKDKGVDAFWHLLSTKEDSTNTLKYLSSLKSV
HHHEEECCCEEEEHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCC
PDPVARTLVSYRKKLKKLTENCINYIPDEAWQSSMVEVEQSVEILKLFKFIDNLLILCPQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
RYGPWGVNKIHEFLLGKRFEKEVHKWVEGTPIMAKSNQPEIGLANGDVGIIIGNGEKRRF
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCEEEEEECCCCCCH
LFNVFSEEQRLVTRLINPSRLNRYDAAYAMTIHKAQGSEADQVLLLWPTTSKVPEEKTFN
HHHHHHHHHHHHHHHCCHHHCCHHHHHEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHH
KFYSDDYEKRMLYTAITRAKKQLLVITNKEEDF
HHHCCCHHHHHHHHHHHHHCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]