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The map label for this gene is gid

Identifier: 124026173

GI number: 124026173

Start: 1173803

End: 1175206

Strand: Direct

Name: gid

Synonym: NATL1_14671

Alternate gene names: 124026173

Gene position: 1173803-1175206 (Clockwise)

Preceding gene: 124026167

Following gene: 124026174

Centisome position: 62.95

GC content: 39.6

Gene sequence:

>1404_bases
TTGAAAGAATATCCATCGGTAACGGTAATAGGCGCTGGCCTGGCAGGATCAGAGGCAGCATGGCAAATAGCAAGCGCAGG
CATAAAAGTAACTCTCTTCGAAATGCGCCCAAAGAAGAAGTCCCCTGCGCACCACTCATCAGAATTTGCAGAATTAGTTT
GCAGTAACAGCTTTGGAGCCCTTAGTAGTGACAGAGCAGCAGGGCTTTTACAAGAAGAGTTAAGAACTTTAAAGTCCATT
GTTATCAACAAGGCTGATAAACACTCTGTCCCGGCAGGAGGGGCACTTGCAGTGGATAGAAGTCAATTCAGTCTGTCAAT
CACAAATGAACTATCTTCTCACCCCCTAATAACAATCATTAGAGATGAGTGTCCATCTTTACCGAAGACTCAACAGATAA
CAATTTTAGCCACAGGTCCTTTAACAAGCGAGTTGCTTGCAGAAGACATCAAAGAATTTACAGGTGAAAAAGAATGTCAT
TTTTTTGATGCTGCCAGTCCGATAATTACTGGAGAAAGTATTGATTTTTCAACAGCATTTCGGGCAAGTAGATACGACAA
AGGCGATGCTGATTACGTTAATTGTCCGATGAATGAAGATTCATACATTAAATTTCACTCTGAATTAATTAAAGCTGAAC
AAGCTAAATTAAAGGACTTTGAAAAAGAATCAGCTCATTTTTTTGAAGGTTGCCTTCCGATAGAACAACTTGCAAAAAGA
GGAATAGATACTATGCGTTATGGGCCATTAAAGCCAATAGGGCTATGGGATCCAAGATGGGGTGATGTGAATGACAAAAA
TATCCGGAGGCTTAAAAGAGCTCATGCGGTCGTTCAATTAAGACAAGAAGACAAGGCTGGTCAATTATGGAATCTCGTTG
GATTTCAAACAAATTTAAAATGGGGGGAACAAAAACGTATATTCAGGATGATTCCAGGCTTATCGAAAGCAGAATTTATT
CGTTTTGGAGTTATGCATAGAAATACTTACCTTGAATCTCCAAAGCTCATAGAACCAACGCTGCAGTTCATAAATAGAAA
AACTTTGTTTGCTGCTGGACAACTCACTGGCACAGAAGGTTATGCTGCTGCTATTGCGGGAGGTTGGCTAGCTGGAACCA
ATGCAGCATTGTTAGCCAAGGGATTAGATACGATTACTTTGCCATCGTCTACAATGATTGGAGCATTAACAAATTTTGTA
AGCAATAGTCAAGCAAGTTTACGAGTTAAAAATAAAAAAAACTTTCAACCAATGCCAGCTAATTTCGGATTACTACCTGA
ACTCGATAATAGAGTTCACAACAAACGTGAAAGGTATAAAGAATATCGAGATAGAGCCTTGGGCCAAATAAAGAAGCTAC
GGGAAACTTTATTGGATAAAAGCTCTTATCCCACGACCATTTAA

Upstream 100 bases:

>100_bases
TTCCTCATTGATTTTTTAGATATTTCCGAAGTCTTAATAAATAGTTGAGGGACATGAGAATATTATTTAATTAAGCTTCT
AAAAAGGAAAACACCACAGC

Downstream 100 bases:

>100_bases
AATCTTTTGAAAATTATGACTCAATCATCAAATAAAGCCAACGATTCTTGCAAGTGGGATTCAATAGTTATTGGTTCCGG
TCTGGGTGGATTAGTAACTG

Product: tRNA (uracil-5-)-methyltransferase Gid

Products: NA

Alternate protein names: Folate-dependent tRNA (uracil-5-)-methyltransferase; Folate-dependent tRNA(M-5-U54)-methyltransferase

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKEYPSVTVIGAGLAGSEAAWQIASAGIKVTLFEMRPKKKSPAHHSSEFAELVCSNSFGALSSDRAAGLLQEELRTLKSI
VINKADKHSVPAGGALAVDRSQFSLSITNELSSHPLITIIRDECPSLPKTQQITILATGPLTSELLAEDIKEFTGEKECH
FFDAASPIITGESIDFSTAFRASRYDKGDADYVNCPMNEDSYIKFHSELIKAEQAKLKDFEKESAHFFEGCLPIEQLAKR
GIDTMRYGPLKPIGLWDPRWGDVNDKNIRRLKRAHAVVQLRQEDKAGQLWNLVGFQTNLKWGEQKRIFRMIPGLSKAEFI
RFGVMHRNTYLESPKLIEPTLQFINRKTLFAAGQLTGTEGYAAAIAGGWLAGTNAALLAKGLDTITLPSSTMIGALTNFV
SNSQASLRVKNKKNFQPMPANFGLLPELDNRVHNKRERYKEYRDRALGQIKKLRETLLDKSSYPTTI

Sequences:

>Translated_467_residues
MKEYPSVTVIGAGLAGSEAAWQIASAGIKVTLFEMRPKKKSPAHHSSEFAELVCSNSFGALSSDRAAGLLQEELRTLKSI
VINKADKHSVPAGGALAVDRSQFSLSITNELSSHPLITIIRDECPSLPKTQQITILATGPLTSELLAEDIKEFTGEKECH
FFDAASPIITGESIDFSTAFRASRYDKGDADYVNCPMNEDSYIKFHSELIKAEQAKLKDFEKESAHFFEGCLPIEQLAKR
GIDTMRYGPLKPIGLWDPRWGDVNDKNIRRLKRAHAVVQLRQEDKAGQLWNLVGFQTNLKWGEQKRIFRMIPGLSKAEFI
RFGVMHRNTYLESPKLIEPTLQFINRKTLFAAGQLTGTEGYAAAIAGGWLAGTNAALLAKGLDTITLPSSTMIGALTNFV
SNSQASLRVKNKKNFQPMPANFGLLPELDNRVHNKRERYKEYRDRALGQIKKLRETLLDKSSYPTTI
>Mature_467_residues
MKEYPSVTVIGAGLAGSEAAWQIASAGIKVTLFEMRPKKKSPAHHSSEFAELVCSNSFGALSSDRAAGLLQEELRTLKSI
VINKADKHSVPAGGALAVDRSQFSLSITNELSSHPLITIIRDECPSLPKTQQITILATGPLTSELLAEDIKEFTGEKECH
FFDAASPIITGESIDFSTAFRASRYDKGDADYVNCPMNEDSYIKFHSELIKAEQAKLKDFEKESAHFFEGCLPIEQLAKR
GIDTMRYGPLKPIGLWDPRWGDVNDKNIRRLKRAHAVVQLRQEDKAGQLWNLVGFQTNLKWGEQKRIFRMIPGLSKAEFI
RFGVMHRNTYLESPKLIEPTLQFINRKTLFAAGQLTGTEGYAAAIAGGWLAGTNAALLAKGLDTITLPSSTMIGALTNFV
SNSQASLRVKNKKNFQPMPANFGLLPELDNRVHNKRERYKEYRDRALGQIKKLRETLLDKSSYPTTI

Specific function: Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs

COG id: COG1206

COG function: function code J; NAD(FAD)-utilizing enzyme possibly involved in translation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family. TrmFO subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRMFO_PROM1 (A2C3G4)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015289.1
- ProteinModelPortal:   A2C3G4
- SMR:   A2C3G4
- STRING:   A2C3G4
- GeneID:   4780984
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_14671
- eggNOG:   COG1206
- HOGENOM:   HBG285041
- OMA:   FEGCLPI
- ProtClustDB:   PRK05335
- BioCyc:   PMAR167555:NATL1_14671-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01037
- InterPro:   IPR004417
- InterPro:   IPR002218
- TIGRFAMs:   TIGR00137

Pfam domain/function: PF01134 GIDA

EC number: =2.1.1.74

Molecular weight: Translated: 51905; Mature: 51905

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEYPSVTVIGAGLAGSEAAWQIASAGIKVTLFEMRPKKKSPAHHSSEFAELVCSNSFGA
CCCCCCEEEEECCCCCCHHHHHHHHCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCC
LSSDRAAGLLQEELRTLKSIVINKADKHSVPAGGALAVDRSQFSLSITNELSSHPLITII
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCEEEEE
RDECPSLPKTQQITILATGPLTSELLAEDIKEFTGEKECHFFDAASPIITGESIDFSTAF
ECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCCHHHHH
RASRYDKGDADYVNCPMNEDSYIKFHSELIKAEQAKLKDFEKESAHFFEGCLPIEQLAKR
HHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
GIDTMRYGPLKPIGLWDPRWGDVNDKNIRRLKRAHAVVQLRQEDKAGQLWNLVGFQTNLK
CCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHCEECCCC
WGEQKRIFRMIPGLSKAEFIRFGVMHRNTYLESPKLIEPTLQFINRKTLFAAGQLTGTEG
CCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHEEEECCCCCCCC
YAAAIAGGWLAGTNAALLAKGLDTITLPSSTMIGALTNFVSNSQASLRVKNKKNFQPMPA
HHHHHHCCCCCCCCHHHHHCCCCEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
NFGLLPELDNRVHNKRERYKEYRDRALGQIKKLRETLLDKSSYPTTI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKEYPSVTVIGAGLAGSEAAWQIASAGIKVTLFEMRPKKKSPAHHSSEFAELVCSNSFGA
CCCCCCEEEEECCCCCCHHHHHHHHCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCC
LSSDRAAGLLQEELRTLKSIVINKADKHSVPAGGALAVDRSQFSLSITNELSSHPLITII
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCEEEEE
RDECPSLPKTQQITILATGPLTSELLAEDIKEFTGEKECHFFDAASPIITGESIDFSTAF
ECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCCHHHHH
RASRYDKGDADYVNCPMNEDSYIKFHSELIKAEQAKLKDFEKESAHFFEGCLPIEQLAKR
HHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
GIDTMRYGPLKPIGLWDPRWGDVNDKNIRRLKRAHAVVQLRQEDKAGQLWNLVGFQTNLK
CCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHCEECCCC
WGEQKRIFRMIPGLSKAEFIRFGVMHRNTYLESPKLIEPTLQFINRKTLFAAGQLTGTEG
CCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHEEEECCCCCCCC
YAAAIAGGWLAGTNAALLAKGLDTITLPSSTMIGALTNFVSNSQASLRVKNKKNFQPMPA
HHHHHHCCCCCCCCHHHHHCCCCEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
NFGLLPELDNRVHNKRERYKEYRDRALGQIKKLRETLLDKSSYPTTI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA