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The map label for this gene is crtH [H]

Identifier: 124026174

GI number: 124026174

Start: 1175222

End: 1176784

Strand: Direct

Name: crtH [H]

Synonym: NATL1_14681

Alternate gene names: 124026174

Gene position: 1175222-1176784 (Clockwise)

Preceding gene: 124026173

Following gene: 124026176

Centisome position: 63.02

GC content: 36.98

Gene sequence:

>1563_bases
ATGACTCAATCATCAAATAAAGCCAACGATTCTTGCAAGTGGGATTCAATAGTTATTGGTTCCGGTCTGGGTGGATTAGT
AACTGCAAGTCAACTAGCAAGCAAAGGTGCAAAGGTGCTTGTTCTAGAACAGTATAAGATTCCGGGTGGAAGTGGTGGAT
CATTTAAAAGAAAAGGATTTACTTTTGATGTTGGAGCATCAATGATCTTTGGGTTTGGTGATAAGGGATACACAAATTTA
CTAACGAGAGCTCTTAAAGATGTTGGACAAAAATGTGAAACGATTCCTGACCCAACACAATTGGCATATCATCTACCCAA
TCAATTAGAAATTTCAGTTGATAGAGATTATCAAAAATTTATTACCAAGCTAATAAATTTATTTCCGCATGAAGAGAAAG
GAATAAAACATTTTTACGAAACATGTTGGGATGTATTTAATTGTCTAGATTCAATGCCTTTACTTTCAATAGAGGATCCT
GCGTATCTAATGAAAGTTTTTTTTAAATCACCTTTATCATGTCTTGGACTGGCTAGGTGGTTGCCAGTTAATGCTGGTGA
TGTTGCTAGGCGATATATTAAAGATCCTGATCTTTTAAGGTTTATAGATATTGAATGTTTCTGCTGGTCAGTTATGCCTG
CCAACTTGACTCCTATGATAAATGCAGGAATGGTCTTTTCTGATAGACATTATGGAGGTATTAACTACCCCAAAGGAGGT
GTAGGAATTATTGCAGAAAAGCTAGTGAAGGGAATTAAAAATCTGGGGGGGGAAGTTAGATATAAATCCAGAGTAAAAAA
AATAATTTTGGAAAACGGAAATGCCATAGGTGTTTCACTTGAAAATGATGAAGAAATTTTCAGTAAAACAGTGGTCTCTA
ATGCTACAAGATGGGATACTTTTGGTGGTCAAGGGATTAAGAGTCCACTTATACCAACAGAGAACAAACCAACGTCTGAG
AAAAAATGGGAAAACAGATATATACCTTCCCCTTCATTCTTATCTCTACATTTGGGAGTGAATGAAGACTCTATACATGC
TAACACTCATTGCCATCATCTACTTCTCGACAAATGGGAAGAAATGGAGAAAGAACAGGGAGTTACTTTCGTATCAATAC
CAACTCTCTTAGATCCCACATTGGCACCTTCAGGTAGCCATATTGTTCATGCTTTTACTCCTTCTTCAATAGATAACTGG
GATGGATTAAGCAATAAAGAATATCTTACAAAGAAAAAAGAAGATGGTGATAAACTTATTTCAAAGTTAGAGAGATTATT
TCCTAACCTAAGTCAAAATATTCTTCACAAAGAAATAGGAAGTCCAAGAACTCATAAAAGATTCCTTGCAAGAAACAAAG
GAAGTTATGGACCAATTCCATCAATGAGATTGCCGGGCCTTCTCCCCATGCCATTCAACACTACTAAAATTAATGGACTT
TATTGTGTTGGGGACTCGTGCTTCCCCGGTCAAGGTTTGAATGCCGTGGCTTTCAGTGGTTATGCCTGTGCTCACAAGAT
AGGCACAAAGCTTGGTATGAACAAATGGGAGCTACCAGAATAA

Upstream 100 bases:

>100_bases
AGAATATCGAGATAGAGCCTTGGGCCAAATAAAGAAGCTACGGGAAACTTTATTGGATAAAAGCTCTTATCCCACGACCA
TTTAAAATCTTTTGAAAATT

Downstream 100 bases:

>100_bases
TTAAAAAATAATTCTAGAAATTATGACGGCAAATTATCAAGACTAAACCTATAGCCCTGCTGGCGAACAGTTGTAATTCC
TCCGCCATCACCTAGACCTG

Product: putative carotenoid isomerase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MTQSSNKANDSCKWDSIVIGSGLGGLVTASQLASKGAKVLVLEQYKIPGGSGGSFKRKGFTFDVGASMIFGFGDKGYTNL
LTRALKDVGQKCETIPDPTQLAYHLPNQLEISVDRDYQKFITKLINLFPHEEKGIKHFYETCWDVFNCLDSMPLLSIEDP
AYLMKVFFKSPLSCLGLARWLPVNAGDVARRYIKDPDLLRFIDIECFCWSVMPANLTPMINAGMVFSDRHYGGINYPKGG
VGIIAEKLVKGIKNLGGEVRYKSRVKKIILENGNAIGVSLENDEEIFSKTVVSNATRWDTFGGQGIKSPLIPTENKPTSE
KKWENRYIPSPSFLSLHLGVNEDSIHANTHCHHLLLDKWEEMEKEQGVTFVSIPTLLDPTLAPSGSHIVHAFTPSSIDNW
DGLSNKEYLTKKKEDGDKLISKLERLFPNLSQNILHKEIGSPRTHKRFLARNKGSYGPIPSMRLPGLLPMPFNTTKINGL
YCVGDSCFPGQGLNAVAFSGYACAHKIGTKLGMNKWELPE

Sequences:

>Translated_520_residues
MTQSSNKANDSCKWDSIVIGSGLGGLVTASQLASKGAKVLVLEQYKIPGGSGGSFKRKGFTFDVGASMIFGFGDKGYTNL
LTRALKDVGQKCETIPDPTQLAYHLPNQLEISVDRDYQKFITKLINLFPHEEKGIKHFYETCWDVFNCLDSMPLLSIEDP
AYLMKVFFKSPLSCLGLARWLPVNAGDVARRYIKDPDLLRFIDIECFCWSVMPANLTPMINAGMVFSDRHYGGINYPKGG
VGIIAEKLVKGIKNLGGEVRYKSRVKKIILENGNAIGVSLENDEEIFSKTVVSNATRWDTFGGQGIKSPLIPTENKPTSE
KKWENRYIPSPSFLSLHLGVNEDSIHANTHCHHLLLDKWEEMEKEQGVTFVSIPTLLDPTLAPSGSHIVHAFTPSSIDNW
DGLSNKEYLTKKKEDGDKLISKLERLFPNLSQNILHKEIGSPRTHKRFLARNKGSYGPIPSMRLPGLLPMPFNTTKINGL
YCVGDSCFPGQGLNAVAFSGYACAHKIGTKLGMNKWELPE
>Mature_519_residues
TQSSNKANDSCKWDSIVIGSGLGGLVTASQLASKGAKVLVLEQYKIPGGSGGSFKRKGFTFDVGASMIFGFGDKGYTNLL
TRALKDVGQKCETIPDPTQLAYHLPNQLEISVDRDYQKFITKLINLFPHEEKGIKHFYETCWDVFNCLDSMPLLSIEDPA
YLMKVFFKSPLSCLGLARWLPVNAGDVARRYIKDPDLLRFIDIECFCWSVMPANLTPMINAGMVFSDRHYGGINYPKGGV
GIIAEKLVKGIKNLGGEVRYKSRVKKIILENGNAIGVSLENDEEIFSKTVVSNATRWDTFGGQGIKSPLIPTENKPTSEK
KWENRYIPSPSFLSLHLGVNEDSIHANTHCHHLLLDKWEEMEKEQGVTFVSIPTLLDPTLAPSGSHIVHAFTPSSIDNWD
GLSNKEYLTKKKEDGDKLISKLERLFPNLSQNILHKEIGSPRTHKRFLARNKGSYGPIPSMRLPGLLPMPFNTTKINGLY
CVGDSCFPGQGLNAVAFSGYACAHKIGTKLGMNKWELPE

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540238, Length=534, Percent_Identity=23.4082397003745, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 57680; Mature: 57549

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSSNKANDSCKWDSIVIGSGLGGLVTASQLASKGAKVLVLEQYKIPGGSGGSFKRKGF
CCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCE
TFDVGASMIFGFGDKGYTNLLTRALKDVGQKCETIPDPTQLAYHLPNQLEISVDRDYQKF
EEECCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEECCCHHHH
ITKLINLFPHEEKGIKHFYETCWDVFNCLDSMPLLSIEDPAYLMKVFFKSPLSCLGLARW
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCHHHHHHHHH
LPVNAGDVARRYIKDPDLLRFIDIECFCWSVMPANLTPMINAGMVFSDRHYGGINYPKGG
CCCCHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCCCEECCCEEEECCCCCCCCCCCCC
VGIIAEKLVKGIKNLGGEVRYKSRVKKIILENGNAIGVSLENDEEIFSKTVVSNATRWDT
HHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCCCC
FGGQGIKSPLIPTENKPTSEKKWENRYIPSPSFLSLHLGVNEDSIHANTHCHHLLLDKWE
CCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
EMEKEQGVTFVSIPTLLDPTLAPSGSHIVHAFTPSSIDNWDGLSNKEYLTKKKEDGDKLI
HHHHHCCCEEEECCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCCHHHHH
SKLERLFPNLSQNILHKEIGSPRTHKRFLARNKGSYGPIPSMRLPGLLPMPFNTTKINGL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECEE
YCVGDSCFPGQGLNAVAFSGYACAHKIGTKLGMNKWELPE
EEECCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TQSSNKANDSCKWDSIVIGSGLGGLVTASQLASKGAKVLVLEQYKIPGGSGGSFKRKGF
CCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCE
TFDVGASMIFGFGDKGYTNLLTRALKDVGQKCETIPDPTQLAYHLPNQLEISVDRDYQKF
EEECCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEECCCHHHH
ITKLINLFPHEEKGIKHFYETCWDVFNCLDSMPLLSIEDPAYLMKVFFKSPLSCLGLARW
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCHHHHHHHHH
LPVNAGDVARRYIKDPDLLRFIDIECFCWSVMPANLTPMINAGMVFSDRHYGGINYPKGG
CCCCHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCCCEECCCEEEECCCCCCCCCCCCC
VGIIAEKLVKGIKNLGGEVRYKSRVKKIILENGNAIGVSLENDEEIFSKTVVSNATRWDT
HHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCCCC
FGGQGIKSPLIPTENKPTSEKKWENRYIPSPSFLSLHLGVNEDSIHANTHCHHLLLDKWE
CCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
EMEKEQGVTFVSIPTLLDPTLAPSGSHIVHAFTPSSIDNWDGLSNKEYLTKKKEDGDKLI
HHHHHCCCEEEECCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCCHHHHH
SKLERLFPNLSQNILHKEIGSPRTHKRFLARNKGSYGPIPSMRLPGLLPMPFNTTKINGL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECEE
YCVGDSCFPGQGLNAVAFSGYACAHKIGTKLGMNKWELPE
EEECCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2254247 [H]