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The map label for this gene is sun [H]

Identifier: 124025193

GI number: 124025193

Start: 437072

End: 438418

Strand: Direct

Name: sun [H]

Synonym: NATL1_04801

Alternate gene names: 124025193

Gene position: 437072-438418 (Clockwise)

Preceding gene: 124025190

Following gene: 124025196

Centisome position: 23.44

GC content: 38.23

Gene sequence:

>1347_bases
TTGCTTTTGAGTGAAAACCTGTCATCCATAAAAGGCTTAGATGCCAGAAAAGCTGCTTGGGAGGTTATCCAAGCCGTAGG
TGGAGGTTCATTCGCAGATGTTGCTTTGGAAAGGATTTTTAATCTTTATTCCTTTAAGTCGATAGATAAAGCTTTGATAA
CTGAACTTTCTTATGGTGCAATTCGCCAAAGATATTACTTGGATTGTTGGATTGATCATTTAGGGAAAGTACCCGCTAAA
AAACAACCTCCTTTATTGAGATGGCTATTGCATCTTGGGCTTTATCAGGTTCTAAAAATGAAGAGAATACCTCCAGCTGC
TGCAATTAACACAACTGTAGAGCTTGCGAAAACTCATCATTTAAGAAAGCTAGCCCCCGTTGTTAATGGAATCTTGCGAT
CTGCTCTTAGAAGCAAAGAGAGAGGACTCTTGTTGCCTAAATCGAATAATCCAAGTTTGGAATTGGCAAAAAACGAGTCA
CTTCCTGTTTGGTTTGCAGAGGAATTGATTGCTTGGAAGGGAGTCGAACATGCTCAGCAGATTGCTAAAGCATTCAACAG
CGTTAGTCCTATTGATATAAGAGTGAATAAATTGCGTGCAGATTTAAAAGATGTAAAAGAACTTTTTGATACCTGCGGTA
TTCAAAATCAATTAATCCCAAACTGTCCTTCCGGATTGGAGGTACGAGCTGGTATAGGTGAACCTAGACAATGGCCTGGT
TATGAAGAAGGTAAATGGAGTGTTCAAGATAGATCTTCACAGTTAATTGCCCCATCATTAGGACCTCTACCTGGAGAAAA
GATTCTTGATGCTTGTGCTGCACCAGGCGGAAAATCAACACATATTGCTGAATTAATTAATAATGAGGGCAATCTCTGGT
CTGTTGATCGATCATCCAGAAGATCTAAAAAAATATTAGCTAACTCAGAGAGGCTTGGGACTAAATGCTTGCAAATATTG
GTTGCTGATTCTAATGAGCTATTACTCAAAAAGCCAGATTGGAAAGGTTTTTTTGATCGTATATTAATAGATGCTCCATG
CTCAGGATTGGGTACTCTTGCTCGCCACCCTGATGCAAGATGGAGGATGAATCAAGATAATATTCAGCAGCTTGTCGCTG
TTCAAAGTCAGTTGCTTAACTCGTTAGCGCCTTTATTGAAAAATGGAGGGAAGTTGGTTTATTCCACTTGTACTATTCAC
CCTGAAGAAAATTCTCATCAGATAAAAAATTTTCTTCAATCTAAGTCTGAGTTTTTATTGGAATATGAAAAACAGATCTG
GCCTGGAGAGGGAGATAATGGAGATGGTTTTTATATTGCTGTTTTAAATAAATTAAAAAATCAATAA

Upstream 100 bases:

>100_bases
CCTGCTATTCCTTGGAAAGTCACTGTAGTAAAAGACTTTTGGGCTTTTGAGCTATGATTATTTCGATAAACATTTTAATG
TGGACTGAACTTTTAAATGA

Downstream 100 bases:

>100_bases
AGGTGATGACGTGTAAACTCGATTTTTAAATAGCTTTGATCTTATTTTTGGTTTTAATGATTAATTTTATAAACTAATTA
AGGAACTATGTCCAATAGCT

Product: Sun protein (Fmu protein)

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MLLSENLSSIKGLDARKAAWEVIQAVGGGSFADVALERIFNLYSFKSIDKALITELSYGAIRQRYYLDCWIDHLGKVPAK
KQPPLLRWLLHLGLYQVLKMKRIPPAAAINTTVELAKTHHLRKLAPVVNGILRSALRSKERGLLLPKSNNPSLELAKNES
LPVWFAEELIAWKGVEHAQQIAKAFNSVSPIDIRVNKLRADLKDVKELFDTCGIQNQLIPNCPSGLEVRAGIGEPRQWPG
YEEGKWSVQDRSSQLIAPSLGPLPGEKILDACAAPGGKSTHIAELINNEGNLWSVDRSSRRSKKILANSERLGTKCLQIL
VADSNELLLKKPDWKGFFDRILIDAPCSGLGTLARHPDARWRMNQDNIQQLVAVQSQLLNSLAPLLKNGGKLVYSTCTIH
PEENSHQIKNFLQSKSEFLLEYEKQIWPGEGDNGDGFYIAVLNKLKNQ

Sequences:

>Translated_448_residues
MLLSENLSSIKGLDARKAAWEVIQAVGGGSFADVALERIFNLYSFKSIDKALITELSYGAIRQRYYLDCWIDHLGKVPAK
KQPPLLRWLLHLGLYQVLKMKRIPPAAAINTTVELAKTHHLRKLAPVVNGILRSALRSKERGLLLPKSNNPSLELAKNES
LPVWFAEELIAWKGVEHAQQIAKAFNSVSPIDIRVNKLRADLKDVKELFDTCGIQNQLIPNCPSGLEVRAGIGEPRQWPG
YEEGKWSVQDRSSQLIAPSLGPLPGEKILDACAAPGGKSTHIAELINNEGNLWSVDRSSRRSKKILANSERLGTKCLQIL
VADSNELLLKKPDWKGFFDRILIDAPCSGLGTLARHPDARWRMNQDNIQQLVAVQSQLLNSLAPLLKNGGKLVYSTCTIH
PEENSHQIKNFLQSKSEFLLEYEKQIWPGEGDNGDGFYIAVLNKLKNQ
>Mature_448_residues
MLLSENLSSIKGLDARKAAWEVIQAVGGGSFADVALERIFNLYSFKSIDKALITELSYGAIRQRYYLDCWIDHLGKVPAK
KQPPLLRWLLHLGLYQVLKMKRIPPAAAINTTVELAKTHHLRKLAPVVNGILRSALRSKERGLLLPKSNNPSLELAKNES
LPVWFAEELIAWKGVEHAQQIAKAFNSVSPIDIRVNKLRADLKDVKELFDTCGIQNQLIPNCPSGLEVRAGIGEPRQWPG
YEEGKWSVQDRSSQLIAPSLGPLPGEKILDACAAPGGKSTHIAELINNEGNLWSVDRSSRRSKKILANSERLGTKCLQIL
VADSNELLLKKPDWKGFFDRILIDAPCSGLGTLARHPDARWRMNQDNIQQLVAVQSQLLNSLAPLLKNGGKLVYSTCTIH
PEENSHQIKNFLQSKSEFLLEYEKQIWPGEGDNGDGFYIAVLNKLKNQ

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=286, Percent_Identity=29.3706293706294, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI76150623, Length=286, Percent_Identity=29.3706293706294, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI32698918, Length=292, Percent_Identity=31.1643835616438, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI39995082, Length=192, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI301336155, Length=192, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI8922322, Length=296, Percent_Identity=27.7027027027027, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI270288818, Length=296, Percent_Identity=27.7027027027027, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI270288816, Length=296, Percent_Identity=27.7027027027027, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI23199998, Length=296, Percent_Identity=27.7027027027027, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI2367212, Length=406, Percent_Identity=36.9458128078818, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI87081985, Length=218, Percent_Identity=33.9449541284404, Blast_Score=108, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17536757, Length=296, Percent_Identity=30.4054054054054, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71998419, Length=171, Percent_Identity=30.4093567251462, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115534021, Length=171, Percent_Identity=30.4093567251462, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25143471, Length=182, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324268, Length=257, Percent_Identity=31.9066147859922, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319447, Length=173, Percent_Identity=34.1040462427746, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI22024126, Length=236, Percent_Identity=31.7796610169492, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24668781, Length=204, Percent_Identity=33.8235294117647, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356513, Length=204, Percent_Identity=33.8235294117647, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355201, Length=184, Percent_Identity=32.0652173913043, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21356579, Length=221, Percent_Identity=26.6968325791855, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920494, Length=179, Percent_Identity=31.2849162011173, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 49949; Mature: 49949

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSENLSSIKGLDARKAAWEVIQAVGGGSFADVALERIFNLYSFKSIDKALITELSYGA
CCCCCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRQRYYLDCWIDHLGKVPAKKQPPLLRWLLHLGLYQVLKMKRIPPAAAINTTVELAKTHH
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LRKLAPVVNGILRSALRSKERGLLLPKSNNPSLELAKNESLPVWFAEELIAWKGVEHAQQ
HHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHH
IAKAFNSVSPIDIRVNKLRADLKDVKELFDTCGIQNQLIPNCPSGLEVRAGIGEPRQWPG
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCC
YEEGKWSVQDRSSQLIAPSLGPLPGEKILDACAAPGGKSTHIAELINNEGNLWSVDRSSR
CCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECCCHHH
RSKKILANSERLGTKCLQILVADSNELLLKKPDWKGFFDRILIDAPCSGLGTLARHPDAR
HHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCHHHHHHCCCCC
WRMNQDNIQQLVAVQSQLLNSLAPLLKNGGKLVYSTCTIHPEENSHQIKNFLQSKSEFLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
EYEKQIWPGEGDNGDGFYIAVLNKLKNQ
HHHHHCCCCCCCCCCEEEEEEHHHHCCC
>Mature Secondary Structure
MLLSENLSSIKGLDARKAAWEVIQAVGGGSFADVALERIFNLYSFKSIDKALITELSYGA
CCCCCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRQRYYLDCWIDHLGKVPAKKQPPLLRWLLHLGLYQVLKMKRIPPAAAINTTVELAKTHH
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LRKLAPVVNGILRSALRSKERGLLLPKSNNPSLELAKNESLPVWFAEELIAWKGVEHAQQ
HHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHH
IAKAFNSVSPIDIRVNKLRADLKDVKELFDTCGIQNQLIPNCPSGLEVRAGIGEPRQWPG
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCC
YEEGKWSVQDRSSQLIAPSLGPLPGEKILDACAAPGGKSTHIAELINNEGNLWSVDRSSR
CCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECCCHHH
RSKKILANSERLGTKCLQILVADSNELLLKKPDWKGFFDRILIDAPCSGLGTLARHPDAR
HHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCHHHHHHCCCCC
WRMNQDNIQQLVAVQSQLLNSLAPLLKNGGKLVYSTCTIHPEENSHQIKNFLQSKSEFLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
EYEKQIWPGEGDNGDGFYIAVLNKLKNQ
HHHHHCCCCCCCCCCEEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]