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The map label for this gene is trxB [H]

Identifier: 124025001

GI number: 124025001

Start: 266931

End: 267887

Strand: Direct

Name: trxB [H]

Synonym: NATL1_02881

Alternate gene names: 124025001

Gene position: 266931-267887 (Clockwise)

Preceding gene: 124025000

Following gene: 124025005

Centisome position: 14.31

GC content: 41.48

Gene sequence:

>957_bases
TTGGAAACCATTGAAACTGATGTTGTCATAGTTGGTGGTGGGCCTGCTGGTTGCAGTTGTGCGCTTTACACCTCCCGAGC
AGATTTAAGAACAGTAATCCTCGATAAGAATCCTGATGTAGGGGCGTTAGCAATAACCCATCAAATTGCGAATTATCCAG
GAGTTTCCAGTGAAATGAGTGGAGAGGCCTTGTTGAAATTGATGAGAGATCAGGCTACCCAATACGGGGCTGATTATCGA
AGAGCTCAAGTTTTTGGAATTGATTCTAGTGGTGACTGGAAAACTATCTACACCCCAGAAGGAACCTTTAAAGCAAAAGC
ACTTGTCGTTGCAAGTGGTGCAATGGGAAGGCCAGCATCATTTAAAGGTGAGGCTGAATTTCTTGGTAGAGGAGTTAGCT
ATTGCGCGACTTGTGATGGGGCTTTTTATAGAGATCGTGAAGTTGCTGTTGTTGGTATTAATAAAGAAGCAATCGAAGAA
GCAAATGTTCTTACAAAATTTGCTTCCAAAGTTCATTGGATAACATCTAATGATCCAAAATCAGATGACCATCATGCGCA
AGACCTCTTATCAAAACCAAATGTCAATCATTGGAGTAAGACTAGGTTAATGCAGATTGAAGGTAATGATGGTGGCGTAA
CAGGTATTAAGGTTAAAAATCGTTCAATTGATACCCTTCAAGATTTAGCTCTTGAAGGAGTTTTTGTTTATATGAGCGGG
TCAAAGCCTATTACTGACTTTCTTGGTGAACAGGTTGCTTTTAAGGAGGATGGCGGGGTTTTGGTGGATGATTTTATGTC
GACAACAGTTGAAGGCGTTTGGGCGATTGGCGACATCAGAAATACCCCTTTTAAGCAAGCTGTTGTAGCAGCATCGGATG
GATGTATAGCCGCTATGGCTATAGATAGATACTTAAATAGTAGAAAATCAATTCGTGTCGACTGGGTTCATGCTTGA

Upstream 100 bases:

>100_bases
GATTTGATTTGGGGAAAAAGTTTAATCTATTAACCCAAGTGATCTCAAAACATTACTTTCTCTTCTTGAAAGAGAGCAAA
ACCTACTAAGAGAATTTCCA

Downstream 100 bases:

>100_bases
TGTGAAAAATTGAGAATTATTTTTTAAAGAGGAGTTGCCTCTGAAACATAAGCAACTCCTCCGTAGTAACTCAGAACAGA
TTTTATATTTTCTCTTATTT

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
METIETDVVIVGGGPAGCSCALYTSRADLRTVILDKNPDVGALAITHQIANYPGVSSEMSGEALLKLMRDQATQYGADYR
RAQVFGIDSSGDWKTIYTPEGTFKAKALVVASGAMGRPASFKGEAEFLGRGVSYCATCDGAFYRDREVAVVGINKEAIEE
ANVLTKFASKVHWITSNDPKSDDHHAQDLLSKPNVNHWSKTRLMQIEGNDGGVTGIKVKNRSIDTLQDLALEGVFVYMSG
SKPITDFLGEQVAFKEDGGVLVDDFMSTTVEGVWAIGDIRNTPFKQAVVAASDGCIAAMAIDRYLNSRKSIRVDWVHA

Sequences:

>Translated_318_residues
METIETDVVIVGGGPAGCSCALYTSRADLRTVILDKNPDVGALAITHQIANYPGVSSEMSGEALLKLMRDQATQYGADYR
RAQVFGIDSSGDWKTIYTPEGTFKAKALVVASGAMGRPASFKGEAEFLGRGVSYCATCDGAFYRDREVAVVGINKEAIEE
ANVLTKFASKVHWITSNDPKSDDHHAQDLLSKPNVNHWSKTRLMQIEGNDGGVTGIKVKNRSIDTLQDLALEGVFVYMSG
SKPITDFLGEQVAFKEDGGVLVDDFMSTTVEGVWAIGDIRNTPFKQAVVAASDGCIAAMAIDRYLNSRKSIRVDWVHA
>Mature_318_residues
METIETDVVIVGGGPAGCSCALYTSRADLRTVILDKNPDVGALAITHQIANYPGVSSEMSGEALLKLMRDQATQYGADYR
RAQVFGIDSSGDWKTIYTPEGTFKAKALVVASGAMGRPASFKGEAEFLGRGVSYCATCDGAFYRDREVAVVGINKEAIEE
ANVLTKFASKVHWITSNDPKSDDHHAQDLLSKPNVNHWSKTRLMQIEGNDGGVTGIKVKNRSIDTLQDLALEGVFVYMSG
SKPITDFLGEQVAFKEDGGVLVDDFMSTTVEGVWAIGDIRNTPFKQAVVAASDGCIAAMAIDRYLNSRKSIRVDWVHA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=314, Percent_Identity=31.8471337579618, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI87081763, Length=310, Percent_Identity=29.3548387096774, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321898, Length=319, Percent_Identity=31.0344827586207, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320560, Length=321, Percent_Identity=28.6604361370716, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34369; Mature: 34369

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIETDVVIVGGGPAGCSCALYTSRADLRTVILDKNPDVGALAITHQIANYPGVSSEMS
CCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEEHHHCCCCCCCCCC
GEALLKLMRDQATQYGADYRRAQVFGIDSSGDWKTIYTPEGTFKAKALVVASGAMGRPAS
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCC
FKGEAEFLGRGVSYCATCDGAFYRDREVAVVGINKEAIEEANVLTKFASKVHWITSNDPK
CCCCHHHHHCCCCEEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCC
SDDHHAQDLLSKPNVNHWSKTRLMQIEGNDGGVTGIKVKNRSIDTLQDLALEGVFVYMSG
CCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCHHHHHHHHHCEEEEEEEC
SKPITDFLGEQVAFKEDGGVLVDDFMSTTVEGVWAIGDIRNTPFKQAVVAASDGCIAAMA
CCCHHHHCCCCEEEECCCCEEHHHHHHHHHHCEEEECCCCCCCHHHEEEECCCCCEEHHH
IDRYLNSRKSIRVDWVHA
HHHHHCCCCCEEEEEEEC
>Mature Secondary Structure
METIETDVVIVGGGPAGCSCALYTSRADLRTVILDKNPDVGALAITHQIANYPGVSSEMS
CCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEEHHHCCCCCCCCCC
GEALLKLMRDQATQYGADYRRAQVFGIDSSGDWKTIYTPEGTFKAKALVVASGAMGRPAS
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCC
FKGEAEFLGRGVSYCATCDGAFYRDREVAVVGINKEAIEEANVLTKFASKVHWITSNDPK
CCCCHHHHHCCCCEEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCC
SDDHHAQDLLSKPNVNHWSKTRLMQIEGNDGGVTGIKVKNRSIDTLQDLALEGVFVYMSG
CCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCHHHHHHHHHCEEEEEEEC
SKPITDFLGEQVAFKEDGGVLVDDFMSTTVEGVWAIGDIRNTPFKQAVVAASDGCIAAMA
CCCHHHHCCCCEEEECCCCEEHHHHHHHHHHCEEEECCCCCCCHHHEEEECCCCCEEHHH
IDRYLNSRKSIRVDWVHA
HHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]