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The map label for this gene is argS

Identifier: 124024975

GI number: 124024975

Start: 239624

End: 241447

Strand: Reverse

Name: argS

Synonym: NATL1_02621

Alternate gene names: 124024975

Gene position: 241447-239624 (Counterclockwise)

Preceding gene: 124024976

Following gene: 124024974

Centisome position: 12.95

GC content: 35.69

Gene sequence:

>1824_bases
ATGCTTGAAATATCCGCCAGATTAGAAGAAGCACTTAATAGAGCTTTCACCAAAGTATTCCCACAAGAGGATCGAAGTTC
AAAAACTTCTTCAATACTTACAGGTTCTAATTTAGTCCCCGCATCCAAGCCTGAATTTGGAGATTTTCAAATAAATTGTG
CTTTATCACTAGCAAAAGAAATCAATCGACCTCCACGGGATATTGCACAACAAATAGCGAAACAACTACAACAAGATAAC
GATTTCGTTAGAATATGTAATCCGCCACTAATTGCAGGTCCAGGTTTCATAAACCTATCTATAAATTCAAAAACACTTAT
ATCTGAAATCCATTTTCGTTTAAATGATAAAAGATTGGGAGTGCCTCTAAAAAAATTCAATACTGACAAAATAGAAGAGG
AGAAAAGTAATAACCGCGTGATTATTGATTTTTCCAGTCCAAATATTGCTAAAGAAATGCATGTTGGGCACTTACGATCA
ACAATTATTGGAGACTCTCTCGCACGGGTTCTTGAATTCTGCGGTTATGAAGTCTTACGACTCAATCATGTAGGGGATTG
GGGTACACAATTTGGCATGCTTATTACTCATCTAAAAGAGGTTGTACCAGAGGTACTCCATACAAAAGATGTAGTAGAAA
TAAGCGATCTCGTGAATTTCTATCGTCAAGCAAAGAAAAGATTTGATGAAGATCAAATCTTTCAAAATAAATCTAGAAGT
GAAGTTGTTAATTTACAAGCAGGTGACAAAGAAAGTCTGATTGCGTGGCAATTACTCTGCAATCAATCCAGAAAAGAGTT
TCAAAAGATCTATGATCGACTTGATATCAAGCTGACTGAAAGAGGGGAATCCTTTTATAACAAATTTTTAGTAGATGTTA
TTAATGATTTAAAAAATAAAAAATTACTAATAAATGATCAAGGAGCTCAATGTATTTTCCTTGATGGCTTAGTTGGAAAA
GATGGTAAACCTCAACCAATAATTATTCAAAAAAGTGACGGAGGTTTTAATTATGCAACCACTGATTTGGCAGCGATTAA
ATACAGATTAACTATTCCTCCGCATGGAGATGGAGCATGCCGTTTAATTTACGTCACAGATGCCGGGCAAGCATCACATT
TCTCTGGAGTTTTTCAAATTGCAAAGCTTGCAAATTGGATTCCCACAGATTGTCAAATCGAGCATGTTCCATTTGGTCTC
GTTCAAGGAGAAGATGGTAAGAAGTTAAAAACTCGTTCTGGTGAGACAATTAGACTAGTAGATCTTCTTGATGAAGCAAT
TCAACGAGCAAGAGACGATCTTAAAAATCGTCTCAATACTGAAAGCAGATCCGAAAATGAAAATTTTATAGATAAAGTTT
CTACTACTGTCGGGATTGCATCAATCAAGTATGCGGATCTAAGTCAAAATAGAATTTCTAATTACCAATTTAGTTTTGAC
AAGATGCTTTCTTTGCAGGGTAATACAGCACCATATTTACTTTATGCATTGGTACGAATTGCCGGAATATCTCGCAAAGG
TGGGGATTTAAATGTATCAAGTCAGAATATTCAGTTTAATGAATCACAAGAATGGGACTTAATTCGCAAGCTATTGCAGC
TTGATTCTATTATCGCTGAAGTAGAAAAAGAACTGCTTCCTAATCGTCTATGCGGGTATTTATTTGAATTAAGTCAGACC
TTTAACAGATTCTATGATCAAGTTCCTATTTTAAAAGCAAGTGAACCTTCAAGAGCCAGTAGACTTGTTTTATGCTCTAT
CACTGCAGATACACTTAAACTGGGGATGAGTTTGCTAGGCATCCCCACTCTGGAGAGAATGTAA

Upstream 100 bases:

>100_bases
AAATGGATAGATTTCAGTATGCGCTTTGACTAAAAAATGAATAAACAGTTTTCTAACAACTTCTAAAAATCCTAAAAGTA
ACTACTTAACCATAAACATC

Downstream 100 bases:

>100_bases
TGGAAAACATAGAAAATTCATTTGTTGATCTACCAAACCCCAGGAAAGATATCGAGGATTTACAGCCATATTCAGCACCA
CTGGAAGGAAGACGAAATTT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MLEISARLEEALNRAFTKVFPQEDRSSKTSSILTGSNLVPASKPEFGDFQINCALSLAKEINRPPRDIAQQIAKQLQQDN
DFVRICNPPLIAGPGFINLSINSKTLISEIHFRLNDKRLGVPLKKFNTDKIEEEKSNNRVIIDFSSPNIAKEMHVGHLRS
TIIGDSLARVLEFCGYEVLRLNHVGDWGTQFGMLITHLKEVVPEVLHTKDVVEISDLVNFYRQAKKRFDEDQIFQNKSRS
EVVNLQAGDKESLIAWQLLCNQSRKEFQKIYDRLDIKLTERGESFYNKFLVDVINDLKNKKLLINDQGAQCIFLDGLVGK
DGKPQPIIIQKSDGGFNYATTDLAAIKYRLTIPPHGDGACRLIYVTDAGQASHFSGVFQIAKLANWIPTDCQIEHVPFGL
VQGEDGKKLKTRSGETIRLVDLLDEAIQRARDDLKNRLNTESRSENENFIDKVSTTVGIASIKYADLSQNRISNYQFSFD
KMLSLQGNTAPYLLYALVRIAGISRKGGDLNVSSQNIQFNESQEWDLIRKLLQLDSIIAEVEKELLPNRLCGYLFELSQT
FNRFYDQVPILKASEPSRASRLVLCSITADTLKLGMSLLGIPTLERM

Sequences:

>Translated_607_residues
MLEISARLEEALNRAFTKVFPQEDRSSKTSSILTGSNLVPASKPEFGDFQINCALSLAKEINRPPRDIAQQIAKQLQQDN
DFVRICNPPLIAGPGFINLSINSKTLISEIHFRLNDKRLGVPLKKFNTDKIEEEKSNNRVIIDFSSPNIAKEMHVGHLRS
TIIGDSLARVLEFCGYEVLRLNHVGDWGTQFGMLITHLKEVVPEVLHTKDVVEISDLVNFYRQAKKRFDEDQIFQNKSRS
EVVNLQAGDKESLIAWQLLCNQSRKEFQKIYDRLDIKLTERGESFYNKFLVDVINDLKNKKLLINDQGAQCIFLDGLVGK
DGKPQPIIIQKSDGGFNYATTDLAAIKYRLTIPPHGDGACRLIYVTDAGQASHFSGVFQIAKLANWIPTDCQIEHVPFGL
VQGEDGKKLKTRSGETIRLVDLLDEAIQRARDDLKNRLNTESRSENENFIDKVSTTVGIASIKYADLSQNRISNYQFSFD
KMLSLQGNTAPYLLYALVRIAGISRKGGDLNVSSQNIQFNESQEWDLIRKLLQLDSIIAEVEKELLPNRLCGYLFELSQT
FNRFYDQVPILKASEPSRASRLVLCSITADTLKLGMSLLGIPTLERM
>Mature_607_residues
MLEISARLEEALNRAFTKVFPQEDRSSKTSSILTGSNLVPASKPEFGDFQINCALSLAKEINRPPRDIAQQIAKQLQQDN
DFVRICNPPLIAGPGFINLSINSKTLISEIHFRLNDKRLGVPLKKFNTDKIEEEKSNNRVIIDFSSPNIAKEMHVGHLRS
TIIGDSLARVLEFCGYEVLRLNHVGDWGTQFGMLITHLKEVVPEVLHTKDVVEISDLVNFYRQAKKRFDEDQIFQNKSRS
EVVNLQAGDKESLIAWQLLCNQSRKEFQKIYDRLDIKLTERGESFYNKFLVDVINDLKNKKLLINDQGAQCIFLDGLVGK
DGKPQPIIIQKSDGGFNYATTDLAAIKYRLTIPPHGDGACRLIYVTDAGQASHFSGVFQIAKLANWIPTDCQIEHVPFGL
VQGEDGKKLKTRSGETIRLVDLLDEAIQRARDDLKNRLNTESRSENENFIDKVSTTVGIASIKYADLSQNRISNYQFSFD
KMLSLQGNTAPYLLYALVRIAGISRKGGDLNVSSQNIQFNESQEWDLIRKLLQLDSIIAEVEKELLPNRLCGYLFELSQT
FNRFYDQVPILKASEPSRASRLVLCSITADTLKLGMSLLGIPTLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=628, Percent_Identity=39.4904458598726, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI197100773, Length=591, Percent_Identity=30.6260575296108, Blast_Score=224, Evalue=2e-58,
Organism=Escherichia coli, GI1788184, Length=574, Percent_Identity=41.8118466898955, Blast_Score=450, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI71985061, Length=624, Percent_Identity=38.3012820512821, Blast_Score=404, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI71985068, Length=603, Percent_Identity=38.971807628524, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17532153, Length=501, Percent_Identity=25.9481037924152, Blast_Score=138, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6320548, Length=559, Percent_Identity=32.5581395348837, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6321883, Length=561, Percent_Identity=29.2335115864528, Blast_Score=201, Evalue=2e-52,
Organism=Drosophila melanogaster, GI18859963, Length=622, Percent_Identity=41.1575562700965, Blast_Score=432, Evalue=1e-121,
Organism=Drosophila melanogaster, GI28571570, Length=487, Percent_Identity=31.006160164271, Blast_Score=183, Evalue=2e-46,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_PROM1 (A2C016)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014091.1
- ProteinModelPortal:   A2C016
- STRING:   A2C016
- GeneID:   4780407
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_02621
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- ProtClustDB:   PRK01611
- BioCyc:   PMAR167555:NATL1_02621-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 68530; Mature: 68530

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEISARLEEALNRAFTKVFPQEDRSSKTSSILTGSNLVPASKPEFGDFQINCALSLAKE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCCCCCCCCCEEEEHHHHHHHH
INRPPRDIAQQIAKQLQQDNDFVRICNPPLIAGPGFINLSINSKTLISEIHFRLNDKRLG
CCCCHHHHHHHHHHHHHCCCCEEEECCCCEEECCCEEEEEECCHHHHHHHHHHCCCCCCC
VPLKKFNTDKIEEEKSNNRVIIDFSSPNIAKEMHVGHLRSTIIGDSLARVLEFCGYEVLR
CCHHHCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LNHVGDWGTQFGMLITHLKEVVPEVLHTKDVVEISDLVNFYRQAKKRFDEDQIFQNKSRS
EECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCH
EVVNLQAGDKESLIAWQLLCNQSRKEFQKIYDRLDIKLTERGESFYNKFLVDVINDLKNK
HEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCC
KLLINDQGAQCIFLDGLVGKDGKPQPIIIQKSDGGFNYATTDLAAIKYRLTIPPHGDGAC
EEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCCCEEHHCEEEEEEEEECCCCCCCCE
RLIYVTDAGQASHFSGVFQIAKLANWIPTDCQIEHVPFGLVQGEDGKKLKTRSGETIRLV
EEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCEEEEECCCCCEEECCCCCEEEHH
DLLDEAIQRARDDLKNRLNTESRSENENFIDKVSTTVGIASIKYADLSQNRISNYQFSFD
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCHHHCCCCEECHH
KMLSLQGNTAPYLLYALVRIAGISRKGGDLNVSSQNIQFNESQEWDLIRKLLQLDSIIAE
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHH
VEKELLPNRLCGYLFELSQTFNRFYDQVPILKASEPSRASRLVLCSITADTLKLGMSLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEECHHHHHHHHHHHC
IPTLERM
CCCCCCC
>Mature Secondary Structure
MLEISARLEEALNRAFTKVFPQEDRSSKTSSILTGSNLVPASKPEFGDFQINCALSLAKE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCCCCCCCCCEEEEHHHHHHHH
INRPPRDIAQQIAKQLQQDNDFVRICNPPLIAGPGFINLSINSKTLISEIHFRLNDKRLG
CCCCHHHHHHHHHHHHHCCCCEEEECCCCEEECCCEEEEEECCHHHHHHHHHHCCCCCCC
VPLKKFNTDKIEEEKSNNRVIIDFSSPNIAKEMHVGHLRSTIIGDSLARVLEFCGYEVLR
CCHHHCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LNHVGDWGTQFGMLITHLKEVVPEVLHTKDVVEISDLVNFYRQAKKRFDEDQIFQNKSRS
EECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCH
EVVNLQAGDKESLIAWQLLCNQSRKEFQKIYDRLDIKLTERGESFYNKFLVDVINDLKNK
HEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCC
KLLINDQGAQCIFLDGLVGKDGKPQPIIIQKSDGGFNYATTDLAAIKYRLTIPPHGDGAC
EEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCCCEEHHCEEEEEEEEECCCCCCCCE
RLIYVTDAGQASHFSGVFQIAKLANWIPTDCQIEHVPFGLVQGEDGKKLKTRSGETIRLV
EEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCEEEEECCCCCEEECCCCCEEEHH
DLLDEAIQRARDDLKNRLNTESRSENENFIDKVSTTVGIASIKYADLSQNRISNYQFSFD
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCHHHCCCCEECHH
KMLSLQGNTAPYLLYALVRIAGISRKGGDLNVSSQNIQFNESQEWDLIRKLLQLDSIIAE
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHH
VEKELLPNRLCGYLFELSQTFNRFYDQVPILKASEPSRASRLVLCSITADTLKLGMSLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEECHHHHHHHHHHHC
IPTLERM
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA