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The map label for this gene is grxC [C]

Identifier: 124024967

GI number: 124024967

Start: 235154

End: 235444

Strand: Reverse

Name: grxC [C]

Synonym: NATL1_02541

Alternate gene names: 124024967

Gene position: 235444-235154 (Counterclockwise)

Preceding gene: 124024974

Following gene: 124024966

Centisome position: 12.63

GC content: 38.83

Gene sequence:

>291_bases
ATGAACAGATCAATTCCCGATTCAGGCATTACTACAGTGGAAATATACACCTGGAGATTTTGCCCGTTTTGCTTACGTGC
CAAAGCACTACTTAATGAAAAAGGAGTCCAATTCACAGAATATTCTATTGATGGAGACGATGGTGCAAGAACAAAAATGT
CTGAAAGAGCCGGAGGCCGCAGAACTGTTCCACAAATTTTTATCAATGGAAAAAGTATTGGAGGTTGCGACGAGCTCTAC
GAACTTGAGAGAAATAACGAATTAAATGAACTGATTGGAATTAGAAATTGA

Upstream 100 bases:

>100_bases
CAATAAAGAAAGGTCTCTTTTAAAATCAGTCAGGTCTTGCAAGCGAAGTAATAGAATCAATACATTAAAAGCTATCAGCA
TATCCACCCAAAAACTATAA

Downstream 100 bases:

>100_bases
TTCATGAAACAACTATTTGTTTTAGATCCAATTGAAAATATCAATCCTAAGAAGGATTCATCAGCAGCACTTATGCAAGC
CGCATCAAGAGCCAACATAG

Product: glutaredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MNRSIPDSGITTVEIYTWRFCPFCLRAKALLNEKGVQFTEYSIDGDDGARTKMSERAGGRRTVPQIFINGKSIGGCDELY
ELERNNELNELIGIRN

Sequences:

>Translated_96_residues
MNRSIPDSGITTVEIYTWRFCPFCLRAKALLNEKGVQFTEYSIDGDDGARTKMSERAGGRRTVPQIFINGKSIGGCDELY
ELERNNELNELIGIRN
>Mature_96_residues
MNRSIPDSGITTVEIYTWRFCPFCLRAKALLNEKGVQFTEYSIDGDDGARTKMSERAGGRRTVPQIFINGKSIGGCDELY
ELERNNELNELIGIRN

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=53.0120481927711, Blast_Score=92, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 10861; Mature: 10861

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSIPDSGITTVEIYTWRFCPFCLRAKALLNEKGVQFTEYSIDGDDGARTKMSERAGGR
CCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHCCCC
RTVPQIFINGKSIGGCDELYELERNNELNELIGIRN
CCCCEEEECCCCCCCHHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure
MNRSIPDSGITTVEIYTWRFCPFCLRAKALLNEKGVQFTEYSIDGDDGARTKMSERAGGR
CCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHCCCC
RTVPQIFINGKSIGGCDELYELERNNELNELIGIRN
CCCCEEEECCCCCCCHHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]