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The map label for this gene is yycF [H]

Identifier: 124024919

GI number: 124024919

Start: 192311

End: 193057

Strand: Direct

Name: yycF [H]

Synonym: NATL1_02061

Alternate gene names: 124024919

Gene position: 192311-193057 (Clockwise)

Preceding gene: 124024917

Following gene: 124024920

Centisome position: 10.31

GC content: 39.09

Gene sequence:

>747_bases
ATGACGGCCACAAGTCCCTCAAAGGAAACCATCCTCGTAGCTGATGATGAGGCAAGCATTAGGAGGATTCTAGAAACTCG
CCTATCCATGATTGGCTATCAGGTAGTTACTGCTTGTGATGGAAATGAGGCTTTGGATCTTTTCAGGAATTGTGAGCCTG
ATTTGGTGGTACTCGATGTCATGATGCCTAAATTAGATGGATATGGAGTTTGCCAGGAACTAAGAAAGGAATCAGATGTT
CCAATAGTTATGCTGACAGCCTTGGGAGATGTTGCAGATAGAATTACAGGACTAGAGCTAGGTGCTGATGATTATGTTGT
TAAACCATTTAGCCCAAAAGAATTAGAAGCTAGGATCAGATGTTTATTAAGAAGGGTAGAGAAAGAACAAATAGCAGGAC
TGCCTAATTCAGGTGTCATTGCGGTTATGAATTTAAAGATTGATACAAATAAGCGTCAGGTTTATAGAAACGATGAACGA
ATTCGATTAACAGGTATGGAATTTAGTCTTTTAGAACTGTTGGTTAGTCGTTCAGGAGAACCTTTTAGTCGAGGTGAGAT
TCTTAAAGAAGTTTGGGGATATACACCTGAAAGACATGTTGATACGAGAGTAGTGGATGTTCATATTTCTAGACTTAGAT
CAAAACTTGAGGATGATCCTGCAAATCCAGAACTAATACTGACTGCAAGAGGAACAGGTTATCTTTTTCAAAGAATTGTT
GACTCTATGATTCCTGAAGGATCATAA

Upstream 100 bases:

>100_bases
TAAAAAGGAAGTTGGCTGTAGTTGAATAAAGATAGTGATCTTTAAATGTTAGTGAACCTTCGCTTAAGATCTTGTCGAAG
CCGCCAAAGCTAAGGAACAA

Downstream 100 bases:

>100_bases
ATAAGTGGAAAAAAATCACCTAAATAATAAAACTAATCGCTCTAAAGCAATTAGAAGATTGGTCATTTGGTATCGCCGAA
ACTCAGCTGTAACAAGTCTT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTATSPSKETILVADDEASIRRILETRLSMIGYQVVTACDGNEALDLFRNCEPDLVVLDVMMPKLDGYGVCQELRKESDV
PIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCLLRRVEKEQIAGLPNSGVIAVMNLKIDTNKRQVYRNDER
IRLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEDDPANPELILTARGTGYLFQRIV
DSMIPEGS

Sequences:

>Translated_248_residues
MTATSPSKETILVADDEASIRRILETRLSMIGYQVVTACDGNEALDLFRNCEPDLVVLDVMMPKLDGYGVCQELRKESDV
PIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCLLRRVEKEQIAGLPNSGVIAVMNLKIDTNKRQVYRNDER
IRLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEDDPANPELILTARGTGYLFQRIV
DSMIPEGS
>Mature_247_residues
TATSPSKETILVADDEASIRRILETRLSMIGYQVVTACDGNEALDLFRNCEPDLVVLDVMMPKLDGYGVCQELRKESDVP
IVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCLLRRVEKEQIAGLPNSGVIAVMNLKIDTNKRQVYRNDERI
RLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEDDPANPELILTARGTGYLFQRIVD
SMIPEGS

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=241, Percent_Identity=41.9087136929461, Blast_Score=174, Evalue=4e-45,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=40.6113537117904, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786784, Length=239, Percent_Identity=37.6569037656904, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=40.2654867256637, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=34.8017621145374, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=37.0044052863436, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=38.6266094420601, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=40.8695652173913, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=34.0425531914894, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=32.5991189427313, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=33.7777777777778, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=36.0515021459227, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=32.5991189427313, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=39.622641509434, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790299, Length=121, Percent_Identity=28.9256198347107, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI145693157, Length=121, Percent_Identity=33.8842975206612, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=35.4545454545455, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=120, Percent_Identity=35.8333333333333, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788192, Length=107, Percent_Identity=36.4485981308411, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27835; Mature: 27704

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATSPSKETILVADDEASIRRILETRLSMIGYQVVTACDGNEALDLFRNCEPDLVVLDV
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCEEEEEE
MMPKLDGYGVCQELRKESDVPIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIR
HHCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCEECCCCEEECCCCCHHHHHHHH
CLLRRVEKEQIAGLPNSGVIAVMNLKIDTNKRQVYRNDERIRLTGMEFSLLELLVSRSGE
HHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHCCCCCEEEEECCHHHHHHHHHHCCCC
PFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEDDPANPELILTARGTGYLFQRIV
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
DSMIPEGS
HHHCCCCC
>Mature Secondary Structure 
TATSPSKETILVADDEASIRRILETRLSMIGYQVVTACDGNEALDLFRNCEPDLVVLDV
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCEEEEEE
MMPKLDGYGVCQELRKESDVPIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIR
HHCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCEECCCCEEECCCCCHHHHHHHH
CLLRRVEKEQIAGLPNSGVIAVMNLKIDTNKRQVYRNDERIRLTGMEFSLLELLVSRSGE
HHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHCCCCCEEEEECCHHHHHHHHHHCCCC
PFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEDDPANPELILTARGTGYLFQRIV
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
DSMIPEGS
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]