Click here to switch to the map view.

The map label for this gene is rpaA [H]

Identifier: 124024913

GI number: 124024913

Start: 185406

End: 186203

Strand: Direct

Name: rpaA [H]

Synonym: NATL1_02001

Alternate gene names: 124024913

Gene position: 185406-186203 (Clockwise)

Preceding gene: 124024912

Following gene: 124024917

Centisome position: 9.94

GC content: 39.22

Gene sequence:

>798_bases
ATGAAGCCTTGCATTTTACTCATTGAAGACGACCAAGACATGAGAGATCTGGTTGCAGGGCATCTTGAGCACACTGGTTT
TGATGTCCAAAAAGCTGAGGACGGCATCAAGGGCCAAGCTTTAGCTCTGCAATATGCGCCAGATCTAATTCTTCTTGATT
TAATGCTTCCTAAAGTTGATGGTTTAACTCTTTGTCAGCGTTTAAGAAGAGATGAGAGAACATCAGCAATACCTATTCTT
ATGATTACTGCTTTAGGTGGAATTAAAGACAAAGTTACGGGTTTTAATTCTGGTGCAGATGATTACATCACAAAACCATT
TGACCTTGAGGAATTACAAGTCAGGATCAAGGCGTTGTTAAGAAGAACTAATCGTGCACCACTAGGAAGTAATAATCAGC
AAGAAATACTCGATTATGGCCCTCTTACACTGGTTCCTGAAAGATTTGAGGCGATATGGTTCGAATCTCCAGTTCGTTTG
ACTCATTTAGAATTTGAATTACTCCATTGTTTGATGCAAAGGCATGGTCAGACCGTTGCACCCTCTTTAATTCTTAAAGA
AGTATGGGGTTACGAGCCTGATGATGATATTGAGACTATTAGGGTGCATGTAAGACATTTAAGAACCAAGCTTGAACCTG
ACCCAAGGAAACCAAGATTCATCAAAACTGTTTACGGTGCAGGATATTGCTTGGAATTACCAACAGGGGACAAAATAAGT
GAGATTCAACCATCAATGATTCAAGCTAGAGAAACCAACTCTTTCAAAAATAATACAGATGAAAGAGTGATTGCTTAA

Upstream 100 bases:

>100_bases
AAATTCTTCGAATTCTGCAATAAAAACAAAATTTTGAGAGAATCATATAAATCTTTAGTAGTCGCTCTGTTGCGGGTACT
TTTTAATTTGGCAATTATTA

Downstream 100 bases:

>100_bases
TTAAGAAAGTTTATTTCTAATAAAGTTACTTCCCAAGCAAGTCTAGGCTGCACAAATTTCAATAATTGTTTTCTAAGCTC
TTCAAGTTGTACAACAATAT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKPCILLIEDDQDMRDLVAGHLEHTGFDVQKAEDGIKGQALALQYAPDLILLDLMLPKVDGLTLCQRLRRDERTSAIPIL
MITALGGIKDKVTGFNSGADDYITKPFDLEELQVRIKALLRRTNRAPLGSNNQQEILDYGPLTLVPERFEAIWFESPVRL
THLEFELLHCLMQRHGQTVAPSLILKEVWGYEPDDDIETIRVHVRHLRTKLEPDPRKPRFIKTVYGAGYCLELPTGDKIS
EIQPSMIQARETNSFKNNTDERVIA

Sequences:

>Translated_265_residues
MKPCILLIEDDQDMRDLVAGHLEHTGFDVQKAEDGIKGQALALQYAPDLILLDLMLPKVDGLTLCQRLRRDERTSAIPIL
MITALGGIKDKVTGFNSGADDYITKPFDLEELQVRIKALLRRTNRAPLGSNNQQEILDYGPLTLVPERFEAIWFESPVRL
THLEFELLHCLMQRHGQTVAPSLILKEVWGYEPDDDIETIRVHVRHLRTKLEPDPRKPRFIKTVYGAGYCLELPTGDKIS
EIQPSMIQARETNSFKNNTDERVIA
>Mature_265_residues
MKPCILLIEDDQDMRDLVAGHLEHTGFDVQKAEDGIKGQALALQYAPDLILLDLMLPKVDGLTLCQRLRRDERTSAIPIL
MITALGGIKDKVTGFNSGADDYITKPFDLEELQVRIKALLRRTNRAPLGSNNQQEILDYGPLTLVPERFEAIWFESPVRL
THLEFELLHCLMQRHGQTVAPSLILKEVWGYEPDDDIETIRVHVRHLRTKLEPDPRKPRFIKTVYGAGYCLELPTGDKIS
EIQPSMIQARETNSFKNNTDERVIA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=38.2222222222222, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=37.0689655172414, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=34.8936170212766, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=35.6828193832599, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=34.061135371179, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=37.6623376623377, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=37.280701754386, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=30.8695652173913, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=36.5217391304348, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=30.9012875536481, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790552, Length=183, Percent_Identity=38.2513661202186, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=29.2372881355932, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=30.1310043668122, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=30.7359307359307, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=29.0598290598291, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=27.2727272727273, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 30164; Mature: 30164

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPCILLIEDDQDMRDLVAGHLEHTGFDVQKAEDGIKGQALALQYAPDLILLDLMLPKVD
CCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCC
GLTLCQRLRRDERTSAIPILMITALGGIKDKVTGFNSGADDYITKPFDLEELQVRIKALL
HHHHHHHHHHHHCCCCCHHHHEEHHCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RRTNRAPLGSNNQQEILDYGPLTLVPERFEAIWFESPVRLTHLEFELLHCLMQRHGQTVA
HHHCCCCCCCCCHHHHHHCCCEEECHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCH
PSLILKEVWGYEPDDDIETIRVHVRHLRTKLEPDPRKPRFIKTVYGAGYCLELPTGDKIS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCCCHH
EIQPSMIQARETNSFKNNTDERVIA
HCCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKPCILLIEDDQDMRDLVAGHLEHTGFDVQKAEDGIKGQALALQYAPDLILLDLMLPKVD
CCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCC
GLTLCQRLRRDERTSAIPILMITALGGIKDKVTGFNSGADDYITKPFDLEELQVRIKALL
HHHHHHHHHHHHCCCCCHHHHEEHHCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RRTNRAPLGSNNQQEILDYGPLTLVPERFEAIWFESPVRLTHLEFELLHCLMQRHGQTVA
HHHCCCCCCCCCHHHHHHCCCEEECHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCH
PSLILKEVWGYEPDDDIETIRVHVRHLRTKLEPDPRKPRFIKTVYGAGYCLELPTGDKIS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCCCHH
EIQPSMIQARETNSFKNNTDERVIA
HCCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]