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The map label for this gene is 124024890

Identifier: 124024890

GI number: 124024890

Start: 169177

End: 169854

Strand: Reverse

Name: 124024890

Synonym: NATL1_01771

Alternate gene names: NA

Gene position: 169854-169177 (Counterclockwise)

Preceding gene: 124024891

Following gene: 124024889

Centisome position: 9.11

GC content: 31.86

Gene sequence:

>678_bases
TTGAAAAAAAAATGGGTTAAATTAGTTTTAGCTTCTAGTATTGATGGACGTATCGCATATCCAGAAGGAGGGAAAACACA
ATTAGGTCAATCTGGTGATCGTTTAGTTTTAGAAGAATCACTGGCTTGGTCAGATGGGATTTTAATGGGAGGGCAAACAC
TGAGGGACCATCAATCAATTTGTTTAATTAAAAATAAAAGCTTACTAAAAAAAAGAACTTCAAAAGGCAAGAACGAACAG
CCAATTGCTCTTATAGCAAGCAATCAAATAGATTTTCCAGAAAATTGGCTTTTTTTTCAACAACCTCTTCAAAGATGGTT
GCTCCAAATGCAAGATAAGAAAAATGAGATTATGCTTCCTGATGGATTCGATAAAAGAATAAATTTAAGAATCACGTGGC
GTGATTCTCTTGATGATTTGTATCAGAAAGGAATTGCGAAAATTGTATTACTTGGAGGTGCAAATCTTATTTCAGCTTTT
CTTTTAGAGAATCTAATAGATGAATTACAAATCACGATTACACCTCATCTTATAGGAGGAGATTACTGCTGGGTTTCATC
TGAATTAAAGAACTTAAATACAATCATGAATAAAAAGAATAACTGGATTCTAAAAGAAAGTAAAAAGCTAGGTAATAACG
AATTACTTATAAGATATTTTAGAAATCATTTATCCTGA

Upstream 100 bases:

>100_bases
ACAGGAAAGTCCTAATAATGCTGCAGAAGTTTATGCAAACCTACCTGAATCAACAATCGATACCAAAGACTCTAAGAATC
AGGTTGGTTTGCTGAGATAA

Downstream 100 bases:

>100_bases
ATATAGATTTAGTATAAAATAAATGAACAATATAAAAATCAAATGGCATGCCACAATCCAAGAAATTCCAAAAATTATTT
GGAATAATTTCTTAAAAGGA

Product: RibD/RibG domain-containing protein

Products: 5-amino-6-(5-phosphoribosylamino)uracil; NADPH; H+

Alternate protein names: RibD/RibG Domain-Containing Protein; Bifunctional Deaminase-Reductase Domain Protein; Pyrimidine Reductase Riboflavin Biosynthesis; Bifunctional Deaminase-Reductase Domain-Containing Protein; Deaminase-Reductase Domain-Containing Protein; Pyrimidine Reductase; Bifunctional Deaminase-Reductase-Like

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKKKWVKLVLASSIDGRIAYPEGGKTQLGQSGDRLVLEESLAWSDGILMGGQTLRDHQSICLIKNKSLLKKRTSKGKNEQ
PIALIASNQIDFPENWLFFQQPLQRWLLQMQDKKNEIMLPDGFDKRINLRITWRDSLDDLYQKGIAKIVLLGGANLISAF
LLENLIDELQITITPHLIGGDYCWVSSELKNLNTIMNKKNNWILKESKKLGNNELLIRYFRNHLS

Sequences:

>Translated_225_residues
MKKKWVKLVLASSIDGRIAYPEGGKTQLGQSGDRLVLEESLAWSDGILMGGQTLRDHQSICLIKNKSLLKKRTSKGKNEQ
PIALIASNQIDFPENWLFFQQPLQRWLLQMQDKKNEIMLPDGFDKRINLRITWRDSLDDLYQKGIAKIVLLGGANLISAF
LLENLIDELQITITPHLIGGDYCWVSSELKNLNTIMNKKNNWILKESKKLGNNELLIRYFRNHLS
>Mature_225_residues
MKKKWVKLVLASSIDGRIAYPEGGKTQLGQSGDRLVLEESLAWSDGILMGGQTLRDHQSICLIKNKSLLKKRTSKGKNEQ
PIALIASNQIDFPENWLFFQQPLQRWLLQMQDKKNEIMLPDGFDKRINLRITWRDSLDDLYQKGIAKIVLLGGANLISAF
LLENLIDELQITITPHLIGGDYCWVSSELKNLNTIMNKKNNWILKESKKLGNNELLIRYFRNHLS

Specific function: Unknown

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.193

Molecular weight: Translated: 25831; Mature: 25831

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKWVKLVLASSIDGRIAYPEGGKTQLGQSGDRLVLEESLAWSDGILMGGQTLRDHQSI
CCCHHEEHEEECCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCCE
CLIKNKSLLKKRTSKGKNEQPIALIASNQIDFPENWLFFQQPLQRWLLQMQDKKNEIMLP
EEEECHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECC
DGFDKRINLRITWRDSLDDLYQKGIAKIVLLGGANLISAFLLENLIDELQITITPHLIGG
CCCCCEEEEEEEECCCHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHEEEEEEEEEECC
DYCWVSSELKNLNTIMNKKNNWILKESKKLGNNELLIRYFRNHLS
CEEEECHHHHHHHHHHCCCCCEEEEHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKKKWVKLVLASSIDGRIAYPEGGKTQLGQSGDRLVLEESLAWSDGILMGGQTLRDHQSI
CCCHHEEHEEECCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCCE
CLIKNKSLLKKRTSKGKNEQPIALIASNQIDFPENWLFFQQPLQRWLLQMQDKKNEIMLP
EEEECHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECC
DGFDKRINLRITWRDSLDDLYQKGIAKIVLLGGANLISAFLLENLIDELQITITPHLIGG
CCCCCEEEEEEEECCCHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHEEEEEEEEEECC
DYCWVSSELKNLNTIMNKKNNWILKESKKLGNNELLIRYFRNHLS
CEEEECHHHHHHHHHHCCCCCEEEEHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-amino-6-(5-phosphoribitylamino)uracil; NADP+

Specific reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP+ = 5-amino-6-(5-phosphoribosylamino)uracil + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA