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The map label for this gene is 124024756

Identifier: 124024756

GI number: 124024756

Start: 45128

End: 46435

Strand: Reverse

Name: 124024756

Synonym: NATL1_00431

Alternate gene names: NA

Gene position: 46435-45128 (Counterclockwise)

Preceding gene: 124024757

Following gene: 124024755

Centisome position: 2.49

GC content: 32.11

Gene sequence:

>1308_bases
ATGGAGGAGTCGCAAAAAGAAGAGCAAAGAAAAAAGAATATACCTCAAGTCCAAACATTTACTGTTCCATTTACCTCAGT
AGAAGTCAAAGAAAACATCACTATTACTACTAATAATCCTTCTAAACCTTCTAAAGAACAAATAATTAATCAAGCAATTC
AGTTTCATCTAAAAGGAAATATTCCAAAAGCAACAAAATATTATCAGCAGTTAATAAATCAAGAATGTAATGATTACAGA
GTTTTTTCTAATTATGGAGCAATTTTACAAGGTCTAGGTAAATCAAAAGAAGCAGAAGCCTCTCTTCGCAAAGCAGTTGA
ACTCAATCCTGATTTAGCCGAGTCGCATTCTTATCTGGGAAACCTATTGAATGATCTTGGAAAATTCAAAGAAGCAGAAG
CCTCTCTTCGTAAAGCCGTTGAACTCAATCCTAATTTAGCCTTGGCGCATGCTTATCTGGGAATCCTATTGAATGATCTT
GGACAATTGAAAGAAGCAGAGGCTAGCCTAAAAAAAGCAATAAAATTAAAATTTGGCTCTGTGAAAGCATATGATGCTTT
ATCAAATGTTCTAAACAAATTAGGGCGCAAAAAAGAAGCAGAGGAAAGTTCTAAGAAGATTTTATATTTAACACCAGTCA
GCGATTCAAAGTTAGAAGATAAAAGAAAAGGCCAAAATAATATGTTTACGAAACCAAGTCCTATAGAGTATCCAATTTTT
TACAGACCAGGTATGGGCACAGAGAATGTTGGGAGTTTTCTTAGATCTATGGTAATGATGTTAAGACCAAAGAGAGTTTT
AGAAATTGGAGCAGGTTATACAACGCCTTTTTTACTAGAAGCATTAATAAATAATGAAAGAGTCTTTGATGATGGGAATC
TAAGTGAGTCTTATTTTCAAAATTATAATTATGAAGCAAAATTAGTCGTTATAGATAATCAATCTTTAGGTAACTTGACA
AAAGTTCCGGGAATGAAAGATATAGTAAATTCAAAGTATACAGAATTTATTGAAGGTACTTTCGAAGGAAAGGCAAAAGA
GTTATCTACAAAATATAGTCATTTTGATTTCGTTTGGTTTGACTGTGGAGGACCCAAGGAATATCTAAGCTTTATTCAAG
AATACTGGGAATATTGTTCAAACTACATTTTATTTCATTTTACTTATCGAGATGGAAAGCCAAATGTGAATCACAAAATC
ATTCACGATAATATAAAAGGAAATCCAGTTATTATAGATATTGTTGAACCACACAAGAAACGACAAGGGAGTATAACAAT
GGTGAAGAAAGAAAATTTTAAAAAATAA

Upstream 100 bases:

>100_bases
TCTCTACCTCAATAAGAGCAGAAAGTTATTTCAAACAGACTGAAATAGAGCTAAGTGTATAGATGTACAATGCGTAAAAT
GAAAGTGTAAAAAAGAGAAA

Downstream 100 bases:

>100_bases
ATCTAAATTATCTCTACAATATAGACATTAGAATTATTCCCACTCAATAGAATTTCGCAAAAGAGCGCCCCTAAACCCCA
GTCATACCAACGGATTTCAT

Product: hypothetical protein

Products: NA

Alternate protein names: Tetratricopeptide TPR_2 Repeat Protein; Tetratricopeptide Repeat Domain Protein; Tetratricopeptide TPR_1 Repeat-Containing Protein; TPR Domain-Containing Protein; Tetratricopeptide Repeat Family; TPR Repeat Protein; O-GlcNAc Transferase; TPR Domain Protein; Methyltransferase Type; Tetratricopeptide Repeat-Containing Protein; Sulfotransferase; Glycosyl Transferase Family Protein; SPY Protein; Tetratricopeptide Tpr_2 Repeat Protein; TPR Domain Containing Protein; Porphyrin Biosynthesis Protein; Peptidase S1 And S6 Chymotrypsin/Hap; O-Linked GlcNAc Transferase; O-Linked N-Acetylglucosamine Transferase; Protein Prenyltransferase Subunit Alpha; Peptidase S; Flp Pilus Assembly Protein TadD; Tetratricopeptide Repeat Domain-Containing Protein; TPR Repeat

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MEESQKEEQRKKNIPQVQTFTVPFTSVEVKENITITTNNPSKPSKEQIINQAIQFHLKGNIPKATKYYQQLINQECNDYR
VFSNYGAILQGLGKSKEAEASLRKAVELNPDLAESHSYLGNLLNDLGKFKEAEASLRKAVELNPNLALAHAYLGILLNDL
GQLKEAEASLKKAIKLKFGSVKAYDALSNVLNKLGRKKEAEESSKKILYLTPVSDSKLEDKRKGQNNMFTKPSPIEYPIF
YRPGMGTENVGSFLRSMVMMLRPKRVLEIGAGYTTPFLLEALINNERVFDDGNLSESYFQNYNYEAKLVVIDNQSLGNLT
KVPGMKDIVNSKYTEFIEGTFEGKAKELSTKYSHFDFVWFDCGGPKEYLSFIQEYWEYCSNYILFHFTYRDGKPNVNHKI
IHDNIKGNPVIIDIVEPHKKRQGSITMVKKENFKK

Sequences:

>Translated_435_residues
MEESQKEEQRKKNIPQVQTFTVPFTSVEVKENITITTNNPSKPSKEQIINQAIQFHLKGNIPKATKYYQQLINQECNDYR
VFSNYGAILQGLGKSKEAEASLRKAVELNPDLAESHSYLGNLLNDLGKFKEAEASLRKAVELNPNLALAHAYLGILLNDL
GQLKEAEASLKKAIKLKFGSVKAYDALSNVLNKLGRKKEAEESSKKILYLTPVSDSKLEDKRKGQNNMFTKPSPIEYPIF
YRPGMGTENVGSFLRSMVMMLRPKRVLEIGAGYTTPFLLEALINNERVFDDGNLSESYFQNYNYEAKLVVIDNQSLGNLT
KVPGMKDIVNSKYTEFIEGTFEGKAKELSTKYSHFDFVWFDCGGPKEYLSFIQEYWEYCSNYILFHFTYRDGKPNVNHKI
IHDNIKGNPVIIDIVEPHKKRQGSITMVKKENFKK
>Mature_435_residues
MEESQKEEQRKKNIPQVQTFTVPFTSVEVKENITITTNNPSKPSKEQIINQAIQFHLKGNIPKATKYYQQLINQECNDYR
VFSNYGAILQGLGKSKEAEASLRKAVELNPDLAESHSYLGNLLNDLGKFKEAEASLRKAVELNPNLALAHAYLGILLNDL
GQLKEAEASLKKAIKLKFGSVKAYDALSNVLNKLGRKKEAEESSKKILYLTPVSDSKLEDKRKGQNNMFTKPSPIEYPIF
YRPGMGTENVGSFLRSMVMMLRPKRVLEIGAGYTTPFLLEALINNERVFDDGNLSESYFQNYNYEAKLVVIDNQSLGNLT
KVPGMKDIVNSKYTEFIEGTFEGKAKELSTKYSHFDFVWFDCGGPKEYLSFIQEYWEYCSNYILFHFTYRDGKPNVNHKI
IHDNIKGNPVIIDIVEPHKKRQGSITMVKKENFKK

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI32307148, Length=165, Percent_Identity=30.3030303030303, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI32307150, Length=165, Percent_Identity=30.3030303030303, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115532692, Length=182, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115532690, Length=182, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17647755, Length=165, Percent_Identity=29.6969696969697, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585827, Length=165, Percent_Identity=29.6969696969697, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585829, Length=165, Percent_Identity=29.6969696969697, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49620; Mature: 49620

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION ; PS00163 FUMARATE_LYASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEESQKEEQRKKNIPQVQTFTVPFTSVEVKENITITTNNPSKPSKEQIINQAIQFHLKGN
CCCHHHHHHHHHCCCCEEEEEECCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHCCCC
IPKATKYYQQLINQECNDYRVFSNYGAILQGLGKSKEAEASLRKAVELNPDLAESHSYLG
CCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
NLLNDLGKFKEAEASLRKAVELNPNLALAHAYLGILLNDLGQLKEAEASLKKAIKLKFGS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VKAYDALSNVLNKLGRKKEAEESSKKILYLTPVSDSKLEDKRKGQNNMFTKPSPIEYPIF
CHHHHHHHHHHHHHCCCHHHHHHCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCEE
YRPGMGTENVGSFLRSMVMMLRPKRVLEIGAGYTTPFLLEALINNERVFDDGNLSESYFQ
ECCCCCHHHHHHHHHHHHHHHCCHHHHEECCCCCHHHHHHHHHCCCEEECCCCCCHHHHH
NYNYEAKLVVIDNQSLGNLTKVPGMKDIVNSKYTEFIEGTFEGKAKELSTKYSHFDFVWF
CCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEE
DCGGPKEYLSFIQEYWEYCSNYILFHFTYRDGKPNVNHKIIHDNIKGNPVIIDIVEPHKK
ECCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEECCCCCCCEEEEEECCCCC
RQGSITMVKKENFKK
CCCCEEEEECCCCCC
>Mature Secondary Structure
MEESQKEEQRKKNIPQVQTFTVPFTSVEVKENITITTNNPSKPSKEQIINQAIQFHLKGN
CCCHHHHHHHHHCCCCEEEEEECCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHCCCC
IPKATKYYQQLINQECNDYRVFSNYGAILQGLGKSKEAEASLRKAVELNPDLAESHSYLG
CCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
NLLNDLGKFKEAEASLRKAVELNPNLALAHAYLGILLNDLGQLKEAEASLKKAIKLKFGS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VKAYDALSNVLNKLGRKKEAEESSKKILYLTPVSDSKLEDKRKGQNNMFTKPSPIEYPIF
CHHHHHHHHHHHHHCCCHHHHHHCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCEE
YRPGMGTENVGSFLRSMVMMLRPKRVLEIGAGYTTPFLLEALINNERVFDDGNLSESYFQ
ECCCCCHHHHHHHHHHHHHHHCCHHHHEECCCCCHHHHHHHHHCCCEEECCCCCCHHHHH
NYNYEAKLVVIDNQSLGNLTKVPGMKDIVNSKYTEFIEGTFEGKAKELSTKYSHFDFVWF
CCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEE
DCGGPKEYLSFIQEYWEYCSNYILFHFTYRDGKPNVNHKIIHDNIKGNPVIIDIVEPHKK
ECCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEECCCCCCCEEEEEECCCCC
RQGSITMVKKENFKK
CCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA