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The map label for this gene is dhsS

Identifier: 124024746

GI number: 124024746

Start: 32708

End: 33862

Strand: Reverse

Name: dhsS

Synonym: NATL1_00331

Alternate gene names: NA

Gene position: 33862-32708 (Counterclockwise)

Preceding gene: 124024749

Following gene: 124024744

Centisome position: 1.82

GC content: 34.55

Gene sequence:

>1155_bases
ATGCAGGACAAACTCAATTTAATGATTCCTGGACCAACACCGGTCCCAGAAAATGTTTTGAGTTCTATGAGTAAACACCC
CATTGGTCATAGAAGTGGAGATTTTCAAAAAATTGTTCAAAAAACAACTGAACAACTCAAATGGCTTCACCAAACAACTG
CAGACGTCCTAACAATTACAGGAAGTGGAACAGCTGCAATGGAGGCAGGAATAATTAATACATTAAGCAAAGGTGATCAA
GTCATTTGCGGCGACAATGGAAAATTTGGTGAAAGATGGGTAAAAGTAGCAAGGGCATATGGATTAGATGTAAAAGTTGT
AAAAGCTGATTGGGGAACCCCTCTTGATCCAAATCAATTTAAGAGGATTCTTGAAGAAGACACCAATGAAAAAATTAAAG
CGGTTATTTTAACTCATTCAGAAACTTCAACAGGAGTGATTAATGATCTTAAATCGATTAATAACGAAGTAAAAAATCAT
AGTAAAGCTATTACAATTGCGGATTGTGTAACAAGTCTTGGTGCATGTAACATCCCAATGGATGAATGGGGAATTGATGT
AATAGCTTCAGGCTCTCAAAAAGGTTATATGATTCCACCTGGCCTGAGTTTTGTTGCTATGAGCAAAAGAGCATGGGAAG
CAAATAATCAATCAAATTTACCTAAGTTTTACTTAGATCTAAAACAATATTTAAAGACAGTTAATCAAAATAGTAATCCT
TTTACGCCTGCAATAAATTTATACTTTGCTTTAGAAGCTTCACTAACAATGATGCAAAAAGAAGGGTTAAATAATATATT
TGCCCGCCATGCTCGTCATCAAAAAGCAACGCAAGAAGGAATAAAAGCAATGGGTTTGAATTTATTTACAAAAGAAAATT
TTGGAAGTCCAGCAATAACAGCTGTTAAGCCTGAAAATATTGACGCTGAAAGTATAAGAAAGGCAATAAAAAATGACTTC
GACATACTCCTTGCTGGAGGTCAAGATCATTTAAAAGGAAAAATCTTTAGAATTGGACATTTAGGATTTGTCAATAATAG
AGACATTATTAGTGTCATATCAGCTTTAGAAAGCACTCTTGATAAAATGGGCAAACTAAACGTCCCCATTGGCCAAGGAA
TTGCAAAAACAATTTCAGTACTAAATAACGAATAA

Upstream 100 bases:

>100_bases
GGGAAGAGTAAATTGATTCAAATCATTGGAAGAGCTGACGATAAAGGAAATTCCCTAAATAATTTTTTAAAATAATCTTA
ATCTAGATTTGAATAAGTAA

Downstream 100 bases:

>100_bases
TATTTAAGAGCTCAACAAATAACTATATTGTTTTAATTAGATGAAGCACTTGAGGCCCTACCCCATCAGCTCTTCTCTCC
TTATCAAGTGCTTTCAAAAT

Product: soluble hydrogenase small subunit

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MQDKLNLMIPGPTPVPENVLSSMSKHPIGHRSGDFQKIVQKTTEQLKWLHQTTADVLTITGSGTAAMEAGIINTLSKGDQ
VICGDNGKFGERWVKVARAYGLDVKVVKADWGTPLDPNQFKRILEEDTNEKIKAVILTHSETSTGVINDLKSINNEVKNH
SKAITIADCVTSLGACNIPMDEWGIDVIASGSQKGYMIPPGLSFVAMSKRAWEANNQSNLPKFYLDLKQYLKTVNQNSNP
FTPAINLYFALEASLTMMQKEGLNNIFARHARHQKATQEGIKAMGLNLFTKENFGSPAITAVKPENIDAESIRKAIKNDF
DILLAGGQDHLKGKIFRIGHLGFVNNRDIISVISALESTLDKMGKLNVPIGQGIAKTISVLNNE

Sequences:

>Translated_384_residues
MQDKLNLMIPGPTPVPENVLSSMSKHPIGHRSGDFQKIVQKTTEQLKWLHQTTADVLTITGSGTAAMEAGIINTLSKGDQ
VICGDNGKFGERWVKVARAYGLDVKVVKADWGTPLDPNQFKRILEEDTNEKIKAVILTHSETSTGVINDLKSINNEVKNH
SKAITIADCVTSLGACNIPMDEWGIDVIASGSQKGYMIPPGLSFVAMSKRAWEANNQSNLPKFYLDLKQYLKTVNQNSNP
FTPAINLYFALEASLTMMQKEGLNNIFARHARHQKATQEGIKAMGLNLFTKENFGSPAITAVKPENIDAESIRKAIKNDF
DILLAGGQDHLKGKIFRIGHLGFVNNRDIISVISALESTLDKMGKLNVPIGQGIAKTISVLNNE
>Mature_384_residues
MQDKLNLMIPGPTPVPENVLSSMSKHPIGHRSGDFQKIVQKTTEQLKWLHQTTADVLTITGSGTAAMEAGIINTLSKGDQ
VICGDNGKFGERWVKVARAYGLDVKVVKADWGTPLDPNQFKRILEEDTNEKIKAVILTHSETSTGVINDLKSINNEVKNH
SKAITIADCVTSLGACNIPMDEWGIDVIASGSQKGYMIPPGLSFVAMSKRAWEANNQSNLPKFYLDLKQYLKTVNQNSNP
FTPAINLYFALEASLTMMQKEGLNNIFARHARHQKATQEGIKAMGLNLFTKENFGSPAITAVKPENIDAESIRKAIKNDF
DILLAGGQDHLKGKIFRIGHLGFVNNRDIISVISALESTLDKMGKLNVPIGQGIAKTISVLNNE

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=370, Percent_Identity=31.3513513513514, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17536281, Length=371, Percent_Identity=27.7628032345013, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6321079, Length=361, Percent_Identity=25.4847645429363, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17530823, Length=346, Percent_Identity=29.4797687861272, Blast_Score=149, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42064; Mature: 42064

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDKLNLMIPGPTPVPENVLSSMSKHPIGHRSGDFQKIVQKTTEQLKWLHQTTADVLTIT
CCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
GSGTAAMEAGIINTLSKGDQVICGDNGKFGERWVKVARAYGLDVKVVKADWGTPLDPNQF
CCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHH
KRILEEDTNEKIKAVILTHSETSTGVINDLKSINNEVKNHSKAITIADCVTSLGACNIPM
HHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEHHHHHHHCCCCCCCH
DEWGIDVIASGSQKGYMIPPGLSFVAMSKRAWEANNQSNLPKFYLDLKQYLKTVNQNSNP
HHCCCEEEECCCCCCEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCC
FTPAINLYFALEASLTMMQKEGLNNIFARHARHQKATQEGIKAMGLNLFTKENFGSPAIT
CCCEEEEEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEE
AVKPENIDAESIRKAIKNDFDILLAGGQDHLKGKIFRIGHLGFVNNRDIISVISALESTL
EECCCCCCHHHHHHHHCCCCEEEEECCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHH
DKMGKLNVPIGQGIAKTISVLNNE
HHHCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MQDKLNLMIPGPTPVPENVLSSMSKHPIGHRSGDFQKIVQKTTEQLKWLHQTTADVLTIT
CCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
GSGTAAMEAGIINTLSKGDQVICGDNGKFGERWVKVARAYGLDVKVVKADWGTPLDPNQF
CCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHH
KRILEEDTNEKIKAVILTHSETSTGVINDLKSINNEVKNHSKAITIADCVTSLGACNIPM
HHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEHHHHHHHCCCCCCCH
DEWGIDVIASGSQKGYMIPPGLSFVAMSKRAWEANNQSNLPKFYLDLKQYLKTVNQNSNP
HHCCCEEEECCCCCCEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCC
FTPAINLYFALEASLTMMQKEGLNNIFARHARHQKATQEGIKAMGLNLFTKENFGSPAIT
CCCEEEEEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEE
AVKPENIDAESIRKAIKNDFDILLAGGQDHLKGKIFRIGHLGFVNNRDIISVISALESTL
EECCCCCCHHHHHHHHCCCCEEEEECCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHH
DKMGKLNVPIGQGIAKTISVLNNE
HHHCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]