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The map label for this gene is efp

Identifier: 124024738

GI number: 124024738

Start: 27900

End: 28463

Strand: Direct

Name: efp

Synonym: NATL1_00251

Alternate gene names: 124024738

Gene position: 27900-28463 (Clockwise)

Preceding gene: 124024735

Following gene: 124024739

Centisome position: 1.5

GC content: 40.6

Gene sequence:

>564_bases
ATGATTTCAAGTAACGACTTTCGCACTGGCACTACGATCGAGTTAGACGGTGCAGTTTGGCGTGTTATTGAATTTCTACA
TGTCAAGCCTGGAAAGGGTTCTGCGTTTGTTAGGACCAAATTAAAGGCTGTTGTGAGCGGTAGTGTTGTCGAAAAAACTT
TTAGAGCTGGAGAAATGGTTCCACAAGCTCTTTTGGAGAAATCAAAGTTGCAACACACATATATGGACGGAGATGAGTTT
GTGTTTATGGATATGACTTCTTATGAAGAAACGCGTCTCACAGCTAAACAAATTGGTGAAAGCAGGAAATATTTAAAGGA
AGGGATGGAGGTTAATGTAGTGTCTTGGAATGAAAAACCTCTTGAAGTGGAATTGCCCAACTCAGTTGTTTTAGAAATAA
AAGAAACTGATCCTGGCGTCAAAGGTGACACTGCTTCTGGAGGAACAAAGCCTGCAATTTTGGAAACAGGAGCCCAAGTC
ATGGTCCCATTATTTATTTCAATTGGTGAGAAAATTCGAGTAGATACTCGAAATGACAGTTATCTAGGCCGAGAGACACA
ATGA

Upstream 100 bases:

>100_bases
TTGTTATCAGGGCAAGAATGCAAATCTTTTTCGCCATTTTAATTCTATGTTTTGCATGACTTTGGCACAGACTTATGATC
GATTGGTATCTTTTGTGTGA

Downstream 100 bases:

>100_bases
CTATGAATCTTGATCACGAAGAGCTTCATCGCTTGTTGGCAACTTTAGCTGAGAGTGACATTAAAGAGTTTCGACTTGAG
GGAGAAGACTTTTGCCTGGA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MISSNDFRTGTTIELDGAVWRVIEFLHVKPGKGSAFVRTKLKAVVSGSVVEKTFRAGEMVPQALLEKSKLQHTYMDGDEF
VFMDMTSYEETRLTAKQIGESRKYLKEGMEVNVVSWNEKPLEVELPNSVVLEIKETDPGVKGDTASGGTKPAILETGAQV
MVPLFISIGEKIRVDTRNDSYLGRETQ

Sequences:

>Translated_187_residues
MISSNDFRTGTTIELDGAVWRVIEFLHVKPGKGSAFVRTKLKAVVSGSVVEKTFRAGEMVPQALLEKSKLQHTYMDGDEF
VFMDMTSYEETRLTAKQIGESRKYLKEGMEVNVVSWNEKPLEVELPNSVVLEIKETDPGVKGDTASGGTKPAILETGAQV
MVPLFISIGEKIRVDTRNDSYLGRETQ
>Mature_187_residues
MISSNDFRTGTTIELDGAVWRVIEFLHVKPGKGSAFVRTKLKAVVSGSVVEKTFRAGEMVPQALLEKSKLQHTYMDGDEF
VFMDMTSYEETRLTAKQIGESRKYLKEGMEVNVVSWNEKPLEVELPNSVVLEIKETDPGVKGDTASGGTKPAILETGAQV
MVPLFISIGEKIRVDTRNDSYLGRETQ

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=181, Percent_Identity=47.5138121546961, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=34.5744680851064, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_PROM1 (A2BZC9)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001013854.1
- ProteinModelPortal:   A2BZC9
- SMR:   A2BZC9
- STRING:   A2BZC9
- GeneID:   4780891
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_00251
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   PMAR167555:NATL1_00251-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20761; Mature: 20761

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSNDFRTGTTIELDGAVWRVIEFLHVKPGKGSAFVRTKLKAVVSGSVVEKTFRAGEMV
CCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
PQALLEKSKLQHTYMDGDEFVFMDMTSYEETRLTAKQIGESRKYLKEGMEVNVVSWNEKP
HHHHHHHHHHHHEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
LEVELPNSVVLEIKETDPGVKGDTASGGTKPAILETGAQVMVPLFISIGEKIRVDTRNDS
EEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCHHHEEHHHHHCCCEEEEECCCCC
YLGRETQ
CCCCCCC
>Mature Secondary Structure
MISSNDFRTGTTIELDGAVWRVIEFLHVKPGKGSAFVRTKLKAVVSGSVVEKTFRAGEMV
CCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
PQALLEKSKLQHTYMDGDEFVFMDMTSYEETRLTAKQIGESRKYLKEGMEVNVVSWNEKP
HHHHHHHHHHHHEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
LEVELPNSVVLEIKETDPGVKGDTASGGTKPAILETGAQVMVPLFISIGEKIRVDTRNDS
EEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCHHHEEHHHHHCCCEEEEECCCCC
YLGRETQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA