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The map label for this gene is murB [H]

Identifier: 124024733

GI number: 124024733

Start: 22213

End: 23088

Strand: Reverse

Name: murB [H]

Synonym: NATL1_00201

Alternate gene names: 124024733

Gene position: 23088-22213 (Counterclockwise)

Preceding gene: 124024734

Following gene: 124024732

Centisome position: 1.24

GC content: 34.36

Gene sequence:

>876_bases
ATGAATTCCATTAAATTACAGAAAAATATTTCCTTATCAAATTTCACTACTTGGGGAATAGGTGGTCCTGCAGAATGGAT
TGCTCAACCAAAAAATATTGAAGAACTTAAATATGTAATTAATTGGACAAATAAGAAAAAAATTCCTTGCAGTGTTATTG
GTGCTGGATCAAATCTTTTAATCAATGACAAAGGAATTAAAGGTTTAAGTCTATGTATGCGTAATCTCAAAGGAATTGAA
ATTGATAAAAACAATGGAATTATCGAAGTCCTTAGCGGTGAAATGCTTCCTACTTTGGCCAGAAAAGCTGCTGCAAGTGG
ACTTCATGGCTTCGAATGGGCTGTAGGAATACCAGGAACAATTGGCGGGGCAGTAGTTATGAATGCAGGAGCACAAGAAC
ATTGCATATCTAGCTATCTCGAAAGTATTACAACGCTATCTTTGACAGGTGAATACCAAAGGATCAAAGGAAAAGATCTA
AACTTTGGATACCGACACAGTCTGCTTCAAAATGAAAAATTAATTGTCGTATCTGCTCGACTCAAGCTGGCATCTGGTCA
TGCAAAAGAAATTCGACAGGTTACAAATGAAAACTTAAATCATCGATTAAAAACTCAACCTTATCAAGCTCAAACCTGCG
GCAGTGTTTTTCGTAATCCAGAACCTTTGAAAGCTGCAAAATTAATTGAAGAACTTGGTTTAAAAGGATTTCGTTTTGGT
GGAGCTGAAATATCCAAAATACATTCAAATTTTATAATTAACGTAAACAAAGCTTCCTCTTATGACGTCAGAGAATTGAT
TAAATATGTCAAAAAAAGAGTTTTTGATTCTTATGGAATCTTGTTAGAAACAGAAGTTAAACAATGTGGCTTTTAA

Upstream 100 bases:

>100_bases
TTTAATTATGGGAGCAGGAGATATTAATCTAATAAGTGAAAATCTATTTTTAGAGTTACTCAATAATAAATTAATCAGCA
ATGATATAGCCGCTTAATAA

Downstream 100 bases:

>100_bases
ATTTAAACCCTAAACTCAATAACAATAGGAAATTCTCATGGCTGGATTCGGACTACCAAATTTTGGACAACTCACTGAAG
CTTTCAAAAAAGCACAACAA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNSIKLQKNISLSNFTTWGIGGPAEWIAQPKNIEELKYVINWTNKKKIPCSVIGAGSNLLINDKGIKGLSLCMRNLKGIE
IDKNNGIIEVLSGEMLPTLARKAAASGLHGFEWAVGIPGTIGGAVVMNAGAQEHCISSYLESITTLSLTGEYQRIKGKDL
NFGYRHSLLQNEKLIVVSARLKLASGHAKEIRQVTNENLNHRLKTQPYQAQTCGSVFRNPEPLKAAKLIEELGLKGFRFG
GAEISKIHSNFIINVNKASSYDVRELIKYVKKRVFDSYGILLETEVKQCGF

Sequences:

>Translated_291_residues
MNSIKLQKNISLSNFTTWGIGGPAEWIAQPKNIEELKYVINWTNKKKIPCSVIGAGSNLLINDKGIKGLSLCMRNLKGIE
IDKNNGIIEVLSGEMLPTLARKAAASGLHGFEWAVGIPGTIGGAVVMNAGAQEHCISSYLESITTLSLTGEYQRIKGKDL
NFGYRHSLLQNEKLIVVSARLKLASGHAKEIRQVTNENLNHRLKTQPYQAQTCGSVFRNPEPLKAAKLIEELGLKGFRFG
GAEISKIHSNFIINVNKASSYDVRELIKYVKKRVFDSYGILLETEVKQCGF
>Mature_291_residues
MNSIKLQKNISLSNFTTWGIGGPAEWIAQPKNIEELKYVINWTNKKKIPCSVIGAGSNLLINDKGIKGLSLCMRNLKGIE
IDKNNGIIEVLSGEMLPTLARKAAASGLHGFEWAVGIPGTIGGAVVMNAGAQEHCISSYLESITTLSLTGEYQRIKGKDL
NFGYRHSLLQNEKLIVVSARLKLASGHAKEIRQVTNENLNHRLKTQPYQAQTCGSVFRNPEPLKAAKLIEELGLKGFRFG
GAEISKIHSNFIINVNKASSYDVRELIKYVKKRVFDSYGILLETEVKQCGF

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=333, Percent_Identity=26.1261261261261, Blast_Score=88, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32088; Mature: 32088

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSIKLQKNISLSNFTTWGIGGPAEWIAQPKNIEELKYVINWTNKKKIPCSVIGAGSNLL
CCCEEEECCCCCCCEEECCCCCCHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCEEE
INDKGIKGLSLCMRNLKGIEIDKNNGIIEVLSGEMLPTLARKAAASGLHGFEWAVGIPGT
EECCCCCHHHHHHHHCCCEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCC
IGGAVVMNAGAQEHCISSYLESITTLSLTGEYQRIKGKDLNFGYRHSLLQNEKLIVVSAR
CCCCEEECCCCHHHHHHHHHHHHHEEEECCCHHHCCCCCCCCHHHHHHHCCCCEEEEEEE
LKLASGHAKEIRQVTNENLNHRLKTQPYQAQTCGSVFRNPEPLKAAKLIEELGLKGFRFG
EEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEC
GAEISKIHSNFIINVNKASSYDVRELIKYVKKRVFDSYGILLETEVKQCGF
CHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEECHHHCCC
>Mature Secondary Structure
MNSIKLQKNISLSNFTTWGIGGPAEWIAQPKNIEELKYVINWTNKKKIPCSVIGAGSNLL
CCCEEEECCCCCCCEEECCCCCCHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCEEE
INDKGIKGLSLCMRNLKGIEIDKNNGIIEVLSGEMLPTLARKAAASGLHGFEWAVGIPGT
EECCCCCHHHHHHHHCCCEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCC
IGGAVVMNAGAQEHCISSYLESITTLSLTGEYQRIKGKDLNFGYRHSLLQNEKLIVVSAR
CCCCEEECCCCHHHHHHHHHHHHHEEEECCCHHHCCCCCCCCHHHHHHHCCCCEEEEEEE
LKLASGHAKEIRQVTNENLNHRLKTQPYQAQTCGSVFRNPEPLKAAKLIEELGLKGFRFG
EEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEC
GAEISKIHSNFIINVNKASSYDVRELIKYVKKRVFDSYGILLETEVKQCGF
CHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA