BacMap

Definition	Hyperthermus butylicus DSM 5456 chromosome, complete genome.
Accession	NC_008818
Length	1,667,163

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The map label for this gene is fabG [H]

Identifier: 124028467

GI number: 124028467

Start: 1628395

End: 1629180

Strand: Direct

Name: fabG [H]

Synonym: Hbut_1627

Alternate gene names: 124028467

Gene position: 1628395-1629180 (Clockwise)

Preceding gene: 124028466

Following gene: 124028468

Centisome position: 97.67

GC content: 54.83

Gene sequence:

>786_bases
ATGCCCTTCAACATTACAGGTATGAAGGTGCTCGTAACAGCTTCTACCCGTGGCATAGGCCGCGGCGTCGCCGAGGTCCT
CCTCGAGGAAGGAGCTCACGTTGTAATTAATGGCCGCACCAGGGAGAGCGTGGAGAAGGCTCTTGAGGCGCTCCGTGGTA
AGGGTAGGGTTTACGGTATTGCCGCCGATCTCTCGGTCAGAGAGGACGTTGAGAGGCTTGTAAAGGAGGCTGCAAGGCTG
ATGGGTGGCCTAGATGCTGTTGTGTACATTGCTGGGCCGCCACGGCCCGGGAAGTTTGAACAGCTAGGTCTAGAGGATTG
GGAGCTTGCTGCTAGGCTACTTGCCCTAAGCGCTGTCTGGATAGCCTACTACTCTCTACCCTACCTCAAGGAGAGCAAAA
ACCCATCGATGGTCTACTTGACCAGTGTTGCCACGAGGGAGCCCCTGGAGGACCTTGCACTCTCAAACACTATGCGTATT
GCTGTCCATGGACTCGTGAGAACTCTCGCAAGAGAGCTTGGAAAGTACGGTATCAGGGTTAACGCGGTAATGCCGGGCTA
CATTCTCACCGACCGAATTAGGCAGATAGCTGAGAAGAGAGCAAAGGAGAGAGGTGTACCTGTCGAGCAGATATACCAGG
AGATGGCGAGCACCATACCTCTCGGCAGAATCGGCGAGCCTCGAGAGGTCGGCTATCTCATAGCATTCCTCATAAGCCCC
TACGCCTCCTACATTAACGGTGCCTCCATACCAATCGATGGCGGCTATCTACGCTCGGTATTCTAG

Upstream 100 bases:

>100_bases
CATCCCATGCTTCAGCTCCATTCCCCGCTACAGATTAACTTGTCAGAGTAACTCTTTACACCTGGCTCTCCAAGCCTCCT
TGCCCTGGAGAGGGGGGACT

Downstream 100 bases:

>100_bases
CAGCCCTCCCCGGAACACCCTAGGGAGAACAAGCCTTGGCAACGCCAGCCAGGAGGATACCTAGGGTAAGGGTTAGGGGT
ATCTACGCGACAGCCCTGAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MPFNITGMKVLVTASTRGIGRGVAEVLLEEGAHVVINGRTRESVEKALEALRGKGRVYGIAADLSVREDVERLVKEAARL
MGGLDAVVYIAGPPRPGKFEQLGLEDWELAARLLALSAVWIAYYSLPYLKESKNPSMVYLTSVATREPLEDLALSNTMRI
AVHGLVRTLARELGKYGIRVNAVMPGYILTDRIRQIAEKRAKERGVPVEQIYQEMASTIPLGRIGEPREVGYLIAFLISP
YASYINGASIPIDGGYLRSVF

Sequences:

>Translated_261_residues
MPFNITGMKVLVTASTRGIGRGVAEVLLEEGAHVVINGRTRESVEKALEALRGKGRVYGIAADLSVREDVERLVKEAARL
MGGLDAVVYIAGPPRPGKFEQLGLEDWELAARLLALSAVWIAYYSLPYLKESKNPSMVYLTSVATREPLEDLALSNTMRI
AVHGLVRTLARELGKYGIRVNAVMPGYILTDRIRQIAEKRAKERGVPVEQIYQEMASTIPLGRIGEPREVGYLIAFLISP
YASYINGASIPIDGGYLRSVF
>Mature_260_residues
PFNITGMKVLVTASTRGIGRGVAEVLLEEGAHVVINGRTRESVEKALEALRGKGRVYGIAADLSVREDVERLVKEAARLM
GGLDAVVYIAGPPRPGKFEQLGLEDWELAARLLALSAVWIAYYSLPYLKESKNPSMVYLTSVATREPLEDLALSNTMRIA
VHGLVRTLARELGKYGIRVNAVMPGYILTDRIRQIAEKRAKERGVPVEQIYQEMASTIPLGRIGEPREVGYLIAFLISPY
ASYINGASIPIDGGYLRSVF

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=34.5528455284553, Blast_Score=128, Evalue=6e-30,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=33.6032388663968, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=31.640625, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI33667109, Length=183, Percent_Identity=37.1584699453552, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=30.5660377358491, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=26.530612244898, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI4503301, Length=228, Percent_Identity=28.0701754385965, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=33.1491712707182, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI66933014, Length=229, Percent_Identity=26.2008733624454, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=24.9027237354086, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI32455239, Length=218, Percent_Identity=25.2293577981651, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI5031765, Length=218, Percent_Identity=25.2293577981651, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI38348362, Length=235, Percent_Identity=27.6595744680851, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4503817, Length=277, Percent_Identity=22.3826714801444, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI38424085, Length=195, Percent_Identity=28.7179487179487, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=33.4630350194552, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=24.7058823529412, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790717, Length=260, Percent_Identity=25.3846153846154, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=28.515625, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=25.2873563218391, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=27.5193798449612, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=27.734375, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=25.2, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=27.9527559055118, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789057, Length=226, Percent_Identity=24.3362831858407, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI2367175, Length=262, Percent_Identity=29.3893129770992, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=32.4110671936759, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=30.6513409961686, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=28.3524904214559, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=255, Percent_Identity=29.8039215686275, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=30, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=27.2030651340996, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=28.4644194756554, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=28.6245353159851, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=28.3088235294118, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=24.901185770751, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=29.8507462686567, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=26.2962962962963, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=25.2, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=28.0898876404494, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=26.5917602996255, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=25.7028112449799, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=26.4150943396226, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=255, Percent_Identity=28.2352941176471, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=24.6212121212121, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=27.1062271062271, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=255, Percent_Identity=25.8823529411765, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=256, Percent_Identity=27.34375, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=26.6409266409266, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=260, Percent_Identity=25, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=128, Percent_Identity=28.90625, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=26.7175572519084, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=27.843137254902, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=33.201581027668, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=29.6875, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=29.2682926829268, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=28.6274509803922, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=30.1587301587302, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=29.7619047619048, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=32.8185328185328, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=26.3565891472868, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28660; Mature: 28529

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFNITGMKVLVTASTRGIGRGVAEVLLEEGAHVVINGRTRESVEKALEALRGKGRVYGI
CCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEEE
AADLSVREDVERLVKEAARLMGGLDAVVYIAGPPRPGKFEQLGLEDWELAARLLALSAVW
EECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHH
IAYYSLPYLKESKNPSMVYLTSVATREPLEDLALSNTMRIAVHGLVRTLARELGKYGIRV
HHHHHCHHHHCCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
NAVMPGYILTDRIRQIAEKRAKERGVPVEQIYQEMASTIPLGRIGEPREVGYLIAFLISP
EEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
YASYINGASIPIDGGYLRSVF
HHHHHCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
PFNITGMKVLVTASTRGIGRGVAEVLLEEGAHVVINGRTRESVEKALEALRGKGRVYGI
CCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEEE
AADLSVREDVERLVKEAARLMGGLDAVVYIAGPPRPGKFEQLGLEDWELAARLLALSAVW
EECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHH
IAYYSLPYLKESKNPSMVYLTSVATREPLEDLALSNTMRIAVHGLVRTLARELGKYGIRV
HHHHHCHHHHCCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
NAVMPGYILTDRIRQIAEKRAKERGVPVEQIYQEMASTIPLGRIGEPREVGYLIAFLISP
EEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
YASYINGASIPIDGGYLRSVF
HHHHHCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]