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The map label for this gene is panE [C]

Identifier: 124028371

GI number: 124028371

Start: 1531883

End: 1532827

Strand: Reverse

Name: panE [C]

Synonym: Hbut_1524

Alternate gene names: 124028371

Gene position: 1532827-1531883 (Counterclockwise)

Preceding gene: 124028372

Following gene: 124028370

Centisome position: 91.94

GC content: 62.43

Gene sequence:

>945_bases
GTGTCCCTCAACATAGATGTGGTTGTTGTGGGTTGCGGGGCTGTTGGGAGCACGGTAGCTCTGGCCTTGGCGAGGGCGGG
TGTGCAGGTGGCAGCGGTTACGAGGAGCGGCACTGACGGGTGCCGCTGGGATATGGTTCTCGTCGAGGGGTTGGGCTTCG
GCGAGCTGCTCGTTTGCGGATGGACGGGTGCAGCGAGGCTCCGCCCGAGGCTCGTAGTCTACGCTGTTAAGGCGTACGAT
TTGACAAGTGCTGTGGAGGATTCTCTCCAGGCAGGCTGGAACCCCGAGGCGGTGGTCTCTCTCCAGAACGGTTTGGGCAG
CCTCGAACTCCTCTCAAAAACCTACGGTGTAGACCGCGCTATAGGCGGCGTGGTCTACTTTGGAGCTGTAGGCGTTGCAC
CGTGCCGCGCCAGGCTCCTCGGGAGGGGAGGGCTGCTGCTGGGTTGCTGGGCGCGCGGTGGTAGCTGCAGCTTCTGGTCC
CACCAGCTTGCAGAGGCACTGACGGCGGGGGGCCTCCCCTCGAGCCATGTGGGCGACGTGGAGCCTTATCGCTGGCTAAA
GCTGGCTGTCAATGCGGCGATAAACCCGGTGACTGTGCTAGCCTGGTCGAGAAACAAGGTCATCCTGGAGAACCCCGATG
CGGGGAAGCTAGCAGCACAGCTGGCCCGCGAGGTTGCCCTAGTAGCTTGGAGGCGGGGAGTCGAGCTACCGGGTGATCCC
GTCGAGGAGGTTTTCCGGGTGGCTAGGGCTACGGGAGACAACTGCTCCTCAATGCTCCAGGACGTGGCGAGGAGGGGACG
TAGCGAGGTAGACTATATCAATGGCTCGGTAGCCCGTGAGGCTTGGAGGCTCGGGCTAAGGGCACCATTCAACGAAGCTA
TGTGGAGAGCTGTGAGGTTGCTAGAGCGATGGCTGGCCGGGAGAAGGTTACCGTGCGAGATATAG

Upstream 100 bases:

>100_bases
GATCCGAAGGCATTCAACAAGACTTGTGTCATGATTCCTCATTCCCTGCTTCTTTTTCTCTTCCATGCCGGGTTGCTTGG
GGCTGGGGTGGCGCTAGACT

Downstream 100 bases:

>100_bases
TTCGTGCTAAGCAGCGCGGAGAGCGCATAGTAATGGTTACGGCTTACGACTACATAACAGCAAAGCTCGTCGACGAAGCC
GGCGTAGATATGATTCTTGT

Product: ketopantoate reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSLNIDVVVVGCGAVGSTVALALARAGVQVAAVTRSGTDGCRWDMVLVEGLGFGELLVCGWTGAARLRPRLVVYAVKAYD
LTSAVEDSLQAGWNPEAVVSLQNGLGSLELLSKTYGVDRAIGGVVYFGAVGVAPCRARLLGRGGLLLGCWARGGSCSFWS
HQLAEALTAGGLPSSHVGDVEPYRWLKLAVNAAINPVTVLAWSRNKVILENPDAGKLAAQLAREVALVAWRRGVELPGDP
VEEVFRVARATGDNCSSMLQDVARRGRSEVDYINGSVAREAWRLGLRAPFNEAMWRAVRLLERWLAGRRLPCEI

Sequences:

>Translated_314_residues
MSLNIDVVVVGCGAVGSTVALALARAGVQVAAVTRSGTDGCRWDMVLVEGLGFGELLVCGWTGAARLRPRLVVYAVKAYD
LTSAVEDSLQAGWNPEAVVSLQNGLGSLELLSKTYGVDRAIGGVVYFGAVGVAPCRARLLGRGGLLLGCWARGGSCSFWS
HQLAEALTAGGLPSSHVGDVEPYRWLKLAVNAAINPVTVLAWSRNKVILENPDAGKLAAQLAREVALVAWRRGVELPGDP
VEEVFRVARATGDNCSSMLQDVARRGRSEVDYINGSVAREAWRLGLRAPFNEAMWRAVRLLERWLAGRRLPCEI
>Mature_313_residues
SLNIDVVVVGCGAVGSTVALALARAGVQVAAVTRSGTDGCRWDMVLVEGLGFGELLVCGWTGAARLRPRLVVYAVKAYDL
TSAVEDSLQAGWNPEAVVSLQNGLGSLELLSKTYGVDRAIGGVVYFGAVGVAPCRARLLGRGGLLLGCWARGGSCSFWSH
QLAEALTAGGLPSSHVGDVEPYRWLKLAVNAAINPVTVLAWSRNKVILENPDAGKLAAQLAREVALVAWRRGVELPGDPV
EEVFRVARATGDNCSSMLQDVARRGRSEVDYINGSVAREAWRLGLRAPFNEAMWRAVRLLERWLAGRRLPCEI

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=311, Percent_Identity=27.0096463022508, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33534; Mature: 33403

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNIDVVVVGCGAVGSTVALALARAGVQVAAVTRSGTDGCRWDMVLVEGLGFGELLVCG
CCCEEEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEECCCCCCEEEEE
WTGAARLRPRLVVYAVKAYDLTSAVEDSLQAGWNPEAVVSLQNGLGSLELLSKTYGVDRA
CCCCHHCCCEEEEEEEEHHHHHHHHHHHHHCCCCCHHEEEECCCCCHHHHHHHHHCHHHH
IGGVVYFGAVGVAPCRARLLGRGGLLLGCWARGGSCSFWSHQLAEALTAGGLPSSHVGDV
HHHHHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
EPYRWLKLAVNAAINPVTVLAWSRNKVILENPDAGKLAAQLAREVALVAWRRGVELPGDP
CHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
VEEVFRVARATGDNCSSMLQDVARRGRSEVDYINGSVAREAWRLGLRAPFNEAMWRAVRL
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHCCCCCHHHHHHHHHHH
LERWLAGRRLPCEI
HHHHHCCCCCCCCC
>Mature Secondary Structure 
SLNIDVVVVGCGAVGSTVALALARAGVQVAAVTRSGTDGCRWDMVLVEGLGFGELLVCG
CCEEEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEECCCCCCEEEEE
WTGAARLRPRLVVYAVKAYDLTSAVEDSLQAGWNPEAVVSLQNGLGSLELLSKTYGVDRA
CCCCHHCCCEEEEEEEEHHHHHHHHHHHHHCCCCCHHEEEECCCCCHHHHHHHHHCHHHH
IGGVVYFGAVGVAPCRARLLGRGGLLLGCWARGGSCSFWSHQLAEALTAGGLPSSHVGDV
HHHHHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
EPYRWLKLAVNAAINPVTVLAWSRNKVILENPDAGKLAAQLAREVALVAWRRGVELPGDP
CHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
VEEVFRVARATGDNCSSMLQDVARRGRSEVDYINGSVAREAWRLGLRAPFNEAMWRAVRL
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHCCCCCHHHHHHHHHHH
LERWLAGRRLPCEI
HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792869 [H]