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The map label for this gene is ubiA [H]

Identifier: 124028189

GI number: 124028189

Start: 1328827

End: 1329726

Strand: Direct

Name: ubiA [H]

Synonym: Hbut_1335

Alternate gene names: 124028189

Gene position: 1328827-1329726 (Clockwise)

Preceding gene: 124028188

Following gene: 124028194

Centisome position: 79.71

GC content: 58.33

Gene sequence:

>900_bases
TTGCCCAGAGCCCTGGAGGTTTTTATCTCAACGAGGCCGTGGAGCTTTCCAATGACCATAGTTTGTGTTGGTTTCGGTAT
AGCGTATGGTTTCTGGCTAACGGGAAGCATCGATGTGCCACTGTCGCTGCTAGCGTTGCTCGGCTCTGTTCTGCTGCACG
CTGCCGCCAACGTCTGGAACGACTACTTCGACTACAGGTATGGTATCGATAGGCCAGGTGTGGGGACGACAGTGTACAGG
CCGCATCCAATATTCGCCAACATCATGGTGCCAGGGCATGTGCTGGTGTTTGGAACCTCTCTGGGGCTCGCAGCCCTGGG
CATCGGATGGGCTCTAGTCTTGGCCGGGCGTCCGCTAGCCCTACTGCTGGGGCTCGCTGGCTTCATCCTGGCCTACTCGT
ACACGGGCCCGCCGCTCAACCTGAAGTACAGGGGTCTCGGCGAGCTCGGGGTCTTCATTGCCTGGGGACCGTTGATGGTT
GTTGGAGGAGCGTACGTGGCTTCGGGGAGCCTCAGCCTGGAGGCTGCTGCGGCCTCTGTGCCTCTGGGCCTGCTGGTGGC
AGCCGTCCTGCTAGCCAACAATATCAGAGATGTCGAGAATGACAGGGAGTCAGGCGCCTACACGCTCGCCGTGAGGATTG
GGAGAAGGTCTGCTATCAAGCTATACCAGTCCATGATACTTGCACCGTATATCATACTAGTCGTACTGTACACCGCAAAG
CTGGTGCCCCTAGCGTCGCTCGTAGCGCTGGCCTCTCTCCCGCTGGCAGTTAGCCTAGCTAGGCTGATGTCGCGCGAGGT
GCCAGTGGATGCTGACCCTAGGACAGCAAAGCTAGTTGTCGCATTCGGTGTACCCTACATACTGGGTACCCTAGCGTCGG
CCATCGCAAACGCTATATAG

Upstream 100 bases:

>100_bases
CTCTGGCTCTACGCTGTCATTCTCGTTGCGCCGGTTAACCTCCTGCTAGGCTAAACATTTTTCCTGGAAGTAGAAAACTC
GTCTCGCTGGGTGGTTCATA

Downstream 100 bases:

>100_bases
AGTGGATGCTATCCATGTTCCTGACTATTTTGTTATTTTGTTATGGGTGGGAACCAAAAGCTGGGTCCTCTCGGCAAGGA
TTCCCAGGGTGTATTGCGGG

Product: prenyltransferase

Products: NA

Alternate protein names: DHNA-octaprenyltransferase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MPRALEVFISTRPWSFPMTIVCVGFGIAYGFWLTGSIDVPLSLLALLGSVLLHAAANVWNDYFDYRYGIDRPGVGTTVYR
PHPIFANIMVPGHVLVFGTSLGLAALGIGWALVLAGRPLALLLGLAGFILAYSYTGPPLNLKYRGLGELGVFIAWGPLMV
VGGAYVASGSLSLEAAAASVPLGLLVAAVLLANNIRDVENDRESGAYTLAVRIGRRSAIKLYQSMILAPYIILVVLYTAK
LVPLASLVALASLPLAVSLARLMSREVPVDADPRTAKLVVAFGVPYILGTLASAIANAI

Sequences:

>Translated_299_residues
MPRALEVFISTRPWSFPMTIVCVGFGIAYGFWLTGSIDVPLSLLALLGSVLLHAAANVWNDYFDYRYGIDRPGVGTTVYR
PHPIFANIMVPGHVLVFGTSLGLAALGIGWALVLAGRPLALLLGLAGFILAYSYTGPPLNLKYRGLGELGVFIAWGPLMV
VGGAYVASGSLSLEAAAASVPLGLLVAAVLLANNIRDVENDRESGAYTLAVRIGRRSAIKLYQSMILAPYIILVVLYTAK
LVPLASLVALASLPLAVSLARLMSREVPVDADPRTAKLVVAFGVPYILGTLASAIANAI
>Mature_298_residues
PRALEVFISTRPWSFPMTIVCVGFGIAYGFWLTGSIDVPLSLLALLGSVLLHAAANVWNDYFDYRYGIDRPGVGTTVYRP
HPIFANIMVPGHVLVFGTSLGLAALGIGWALVLAGRPLALLLGLAGFILAYSYTGPPLNLKYRGLGELGVFIAWGPLMVV
GGAYVASGSLSLEAAAASVPLGLLVAAVLLANNIRDVENDRESGAYTLAVRIGRRSAIKLYQSMILAPYIILVVLYTAKL
VPLASLVALASLPLAVSLARLMSREVPVDADPRTAKLVVAFGVPYILGTLASAIANAI

Specific function: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK). Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA. The conversion of DHNA to DMK proceeds in three stages:the removal of the carboxyl group of DHNA

COG id: COG1575

COG function: function code H; 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the menA family [H]

Homologues:

Organism=Homo sapiens, GI7019551, Length=287, Percent_Identity=32.0557491289199, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1790365, Length=298, Percent_Identity=30.5369127516779, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17737429, Length=289, Percent_Identity=30.1038062283737, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004657
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: =2.5.1.74 [H]

Molecular weight: Translated: 31548; Mature: 31417

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRALEVFISTRPWSFPMTIVCVGFGIAYGFWLTGSIDVPLSLLALLGSVLLHAAANVWN
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DYFDYRYGIDRPGVGTTVYRPHPIFANIMVPGHVLVFGTSLGLAALGIGWALVLAGRPLA
HHHHHCCCCCCCCCCCEEECCCCCEEEEECCCEEEEEECHHHHHHHHHHHHHHHCCCHHH
LLLGLAGFILAYSYTGPPLNLKYRGLGELGVFIAWGPLMVVGGAYVASGSLSLEAAAASV
HHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCHHEECCCCEEHHHHHHC
PLGLLVAAVLLANNIRDVENDRESGAYTLAVRIGRRSAIKLYQSMILAPYIILVVLYTAK
CHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
LVPLASLVALASLPLAVSLARLMSREVPVDADPRTAKLVVAFGVPYILGTLASAIANAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRALEVFISTRPWSFPMTIVCVGFGIAYGFWLTGSIDVPLSLLALLGSVLLHAAANVWN
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DYFDYRYGIDRPGVGTTVYRPHPIFANIMVPGHVLVFGTSLGLAALGIGWALVLAGRPLA
HHHHHCCCCCCCCCCCEEECCCCCEEEEECCCEEEEEECHHHHHHHHHHHHHHHCCCHHH
LLLGLAGFILAYSYTGPPLNLKYRGLGELGVFIAWGPLMVVGGAYVASGSLSLEAAAASV
HHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCHHEECCCCEEHHHHHHC
PLGLLVAAVLLANNIRDVENDRESGAYTLAVRIGRRSAIKLYQSMILAPYIILVVLYTAK
CHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
LVPLASLVALASLPLAVSLARLMSREVPVDADPRTAKLVVAFGVPYILGTLASAIANAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]