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The map label for this gene is glnA [H]

Identifier: 124028054

GI number: 124028054

Start: 1205741

End: 1207144

Strand: Direct

Name: glnA [H]

Synonym: Hbut_1195

Alternate gene names: 124028054

Gene position: 1205741-1207144 (Clockwise)

Preceding gene: 124028052

Following gene: 124028055

Centisome position: 72.32

GC content: 50.43

Gene sequence:

>1404_bases
TTGATTCCAGGCGAAAGGATGTCTGGAACTCCAGGTTCAGATCTGGACAAATTCAAGTGGTTAGAGCTGCACTACACAGA
CCTGGCTGGCTATCTGAGGAGTGTTACTATCGCAGCGGAGGATCTCAGAGACAATGTCGACGTAACAGGCTTTGATGGTA
GTAGTGTTGAAGGCTTCACGGATATAAGTGATAGTGATCTAACACTGCGTCCAGATCTAAGTACATTGGCTGAGATACCA
TGGCTAGAGGCTACGGGGAGGGTAATATCAACAATATACAAGAATGGTGCTAGGTATGAGCGTGATCCACGCTACATTGC
TGAACGTACTGAAAAGCTTCTTGGCGAACAAGGCCTTGAGGCTCGTATAGGTCCCGAAATAGAGTTCCACATAGTAGACA
AGCTATACCTTAGTGTTGACCAGCCACAGCGCGGACTATGTTACCGCATAGTTTCAAGTGAACACCCCGGCAGTGGCAGC
TATTTCGAGAAGACTAAGAAGGCATACCACACACCGGCACCCTTCGACAAAGTTTACGGGCTGCGGCTCGAGCTAGCCGA
GGTTCTAAGGAAATACTTCAGAGTACATGTAGAGGTTCACCACCACGAGGTTGCTAGTGGCGGACAGATTGAGATAGACT
TCCGTTATGGTGGCGTGGTATCAGCTTCTGATGGGGTTATCACGGTCAAATACGTTGCAAGGAATATTACTGCAAGGCAT
GGCTATACTGCAATCTTTATGCCTAAGCCGTTCGCTGGCGATAACGGGAATGGGATGCACGTACATATCAGCATTTGGGA
GCGTCGCGGGAATGGTTTTAGAAACTTGTTCTATGACCCATCAGACGGTTATGCAGAACTGAGCCAGTACGCTAGGTACT
TTATCGGGGGTCTCTTAGAGCATGGGAGAGCTCTTGCAGCAATCGTGGCACCAACCGTGAATAGTTACCGTAGGCTAATA
CCAGGCTACGAGGCTCCAGTCTACCTCGTCTGGGGAAGGAGTAACCGTAGCGCAGCCATCCGTGTACCATTCTACGGCCG
GGGTGCAGAGAAGTCTAAACGCATAGAATTTAGGCCCCCCGACCCCTCCGCCAACCCATACCTGGCCTTCACCGCCATAA
TTGCAGCCGGCCTAGATGGTGTGAGAAAGAAGATCGAGCCGGGCGACCCCATAGACCGTAACGTCTATACTATGAGCGAG
GCTGAGAAGAAGCGGCTCGGGATAAAGGAGCTGCCTAGAAGCCTAGAGGAGGCGCTAGACGAGCTAGAGTCAGACAACGA
GTTCCTACGACCATACATACCGTCAAGCGTTCTTGAAGCCTACATAGAGCTTAAGCGGCGTGAAGCCAGGGAGCTTAAAG
GATATCCAAGCCCAATGGAGATCTACACATACCTCTCACTCTAA

Upstream 100 bases:

>100_bases
ATCTAACCCTAGTTTGGTTTACCGGTACAGACCACACAACAACAAAAAACAAAATTTCGAAGCACACGAGAGGAACACAT
AATATGTTGTACTGAGGAGC

Downstream 100 bases:

>100_bases
CACAACTATCAAATCTTGTTTTCGCCTTATAAGCTTCAGACCTTACAGTACGGAATTTATGGCCCAGCCGGTGAGGAGGG
CTCCGGGCGTAGCCGAGTAA

Product: glutamine synthetase

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MIPGERMSGTPGSDLDKFKWLELHYTDLAGYLRSVTIAAEDLRDNVDVTGFDGSSVEGFTDISDSDLTLRPDLSTLAEIP
WLEATGRVISTIYKNGARYERDPRYIAERTEKLLGEQGLEARIGPEIEFHIVDKLYLSVDQPQRGLCYRIVSSEHPGSGS
YFEKTKKAYHTPAPFDKVYGLRLELAEVLRKYFRVHVEVHHHEVASGGQIEIDFRYGGVVSASDGVITVKYVARNITARH
GYTAIFMPKPFAGDNGNGMHVHISIWERRGNGFRNLFYDPSDGYAELSQYARYFIGGLLEHGRALAAIVAPTVNSYRRLI
PGYEAPVYLVWGRSNRSAAIRVPFYGRGAEKSKRIEFRPPDPSANPYLAFTAIIAAGLDGVRKKIEPGDPIDRNVYTMSE
AEKKRLGIKELPRSLEEALDELESDNEFLRPYIPSSVLEAYIELKRREARELKGYPSPMEIYTYLSL

Sequences:

>Translated_467_residues
MIPGERMSGTPGSDLDKFKWLELHYTDLAGYLRSVTIAAEDLRDNVDVTGFDGSSVEGFTDISDSDLTLRPDLSTLAEIP
WLEATGRVISTIYKNGARYERDPRYIAERTEKLLGEQGLEARIGPEIEFHIVDKLYLSVDQPQRGLCYRIVSSEHPGSGS
YFEKTKKAYHTPAPFDKVYGLRLELAEVLRKYFRVHVEVHHHEVASGGQIEIDFRYGGVVSASDGVITVKYVARNITARH
GYTAIFMPKPFAGDNGNGMHVHISIWERRGNGFRNLFYDPSDGYAELSQYARYFIGGLLEHGRALAAIVAPTVNSYRRLI
PGYEAPVYLVWGRSNRSAAIRVPFYGRGAEKSKRIEFRPPDPSANPYLAFTAIIAAGLDGVRKKIEPGDPIDRNVYTMSE
AEKKRLGIKELPRSLEEALDELESDNEFLRPYIPSSVLEAYIELKRREARELKGYPSPMEIYTYLSL
>Mature_467_residues
MIPGERMSGTPGSDLDKFKWLELHYTDLAGYLRSVTIAAEDLRDNVDVTGFDGSSVEGFTDISDSDLTLRPDLSTLAEIP
WLEATGRVISTIYKNGARYERDPRYIAERTEKLLGEQGLEARIGPEIEFHIVDKLYLSVDQPQRGLCYRIVSSEHPGSGS
YFEKTKKAYHTPAPFDKVYGLRLELAEVLRKYFRVHVEVHHHEVASGGQIEIDFRYGGVVSASDGVITVKYVARNITARH
GYTAIFMPKPFAGDNGNGMHVHISIWERRGNGFRNLFYDPSDGYAELSQYARYFIGGLLEHGRALAAIVAPTVNSYRRLI
PGYEAPVYLVWGRSNRSAAIRVPFYGRGAEKSKRIEFRPPDPSANPYLAFTAIIAAGLDGVRKKIEPGDPIDRNVYTMSE
AEKKRLGIKELPRSLEEALDELESDNEFLRPYIPSSVLEAYIELKRREARELKGYPSPMEIYTYLSL

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=430, Percent_Identity=25.5813953488372, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1790301, Length=469, Percent_Identity=39.0191897654584, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI87081870, Length=463, Percent_Identity=27.2138228941685, Blast_Score=126, Evalue=4e-30,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 52674; Mature: 52674

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPGERMSGTPGSDLDKFKWLELHYTDLAGYLRSVTIAAEDLRDNVDVTGFDGSSVEGFT
CCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCC
DISDSDLTLRPDLSTLAEIPWLEATGRVISTIYKNGARYERDPRYIAERTEKLLGEQGLE
CCCCCCEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
ARIGPEIEFHIVDKLYLSVDQPQRGLCYRIVSSEHPGSGSYFEKTKKAYHTPAPFDKVYG
CCCCCCEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHH
LRLELAEVLRKYFRVHVEVHHHEVASGGQIEIDFRYGGVVSASDGVITVKYVARNITARH
HHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEEEEECCEEECCCCEEEEEEHHHHHHHCC
GYTAIFMPKPFAGDNGNGMHVHISIWERRGNGFRNLFYDPSDGYAELSQYARYFIGGLLE
CEEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HGRALAAIVAPTVNSYRRLIPGYEAPVYLVWGRSNRSAAIRVPFYGRGAEKSKRIEFRPP
CCCCEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCEEECCC
DPSANPYLAFTAIIAAGLDGVRKKIEPGDPIDRNVYTMSEAEKKRLGIKELPRSLEEALD
CCCCCCHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEHHHHHHHCCCHHHHHHHHHHHHH
ELESDNEFLRPYIPSSVLEAYIELKRREARELKGYPSPMEIYTYLSL
HHCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure
MIPGERMSGTPGSDLDKFKWLELHYTDLAGYLRSVTIAAEDLRDNVDVTGFDGSSVEGFT
CCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCC
DISDSDLTLRPDLSTLAEIPWLEATGRVISTIYKNGARYERDPRYIAERTEKLLGEQGLE
CCCCCCEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
ARIGPEIEFHIVDKLYLSVDQPQRGLCYRIVSSEHPGSGSYFEKTKKAYHTPAPFDKVYG
CCCCCCEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHH
LRLELAEVLRKYFRVHVEVHHHEVASGGQIEIDFRYGGVVSASDGVITVKYVARNITARH
HHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEEEEECCEEECCCCEEEEEEHHHHHHHCC
GYTAIFMPKPFAGDNGNGMHVHISIWERRGNGFRNLFYDPSDGYAELSQYARYFIGGLLE
CEEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HGRALAAIVAPTVNSYRRLIPGYEAPVYLVWGRSNRSAAIRVPFYGRGAEKSKRIEFRPP
CCCCEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCEEECCC
DPSANPYLAFTAIIAAGLDGVRKKIEPGDPIDRNVYTMSEAEKKRLGIKELPRSLEEALD
CCCCCCHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEHHHHHHHCCCHHHHHHHHHHHHH
ELESDNEFLRPYIPSSVLEAYIELKRREARELKGYPSPMEIYTYLSL
HHCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9865608 [H]